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Recommended hotels in Southeast Missouri

Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1000)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is ₩129,948
₩149,399 total
includes taxes & fees
Dec 29 - Dec 30
Drury Inn & Suites Sikeston, MO
Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
9.4 out of 10, Exceptional, (857)
"The rooms were very clean and well maintained and th e staff was great and the young lady who checked us in was awsome at her job she helped me get the smart tv workin and has a very professional and respectfull through the hole stay we thank this is the nicest hotel i ve stayed at by far andcwill be back "
United States
Terry
The price is ₩150,179
₩169,665 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Fairfield Inn & Suites by Marriott Poplar Bluff
Front of property
Echo Bluff State Park

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
9.6 out of 10, Exceptional, (217)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is ₩229,601
₩242,746 total
includes taxes & fees
Dec 28 - Dec 29
Echo Bluff State Park
Front of property
The Farmstead Hotel

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
8.8 out of 10, Excellent, (463)
"Nice place "
United States
Debbie
The price is ₩123,465
₩140,410 total
includes taxes & fees
Dec 26 - Dec 27
The Farmstead Hotel
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is ₩129,948
₩146,583 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
9.2 out of 10, Wonderful, (543)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
The price is ₩128,733
₩147,367 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express & Suites Perryville by IHG
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1009)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ₩109,226
₩124,489 total
includes taxes & fees
Dec 29 - Dec 30
Best Western Plus Sikeston
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
9.2 out of 10, Wonderful, (968)
"Nice room helpful staff. "
United States
Deborah
The price is ₩154,497
₩174,555 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Drury Inn & Suites Poplar Bluff
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ₩103,564
₩116,837 total
includes taxes & fees
Dec 29 - Dec 30
Pear Tree Inn Cape Girardeau Near the Medical Center
Outdoor pool, sun loungers
Fort Davidson Hotel

Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
9.2 out of 10, Wonderful, (174)
"Friendly staff, spacious room, nice pool!!"
United States
SHARON
The price is ₩177,563
₩193,943 total
includes taxes & fees
Dec 26 - Dec 27
Fort Davidson Hotel
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
9.6 out of 10, Exceptional, (1002)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is ₩122,799
₩129,828 total
includes taxes & fees
Dec 28 - Dec 29
Drury Inn & Suites Jackson MO
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
8.8 out of 10, Excellent, (707)
"Amazing place"
United States
Mladen
The price is ₩155,367
₩175,520 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Poplar Bluff by IHG
Terrace/patio
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
9.4 out of 10, Exceptional, (797)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is ₩162,988
₩182,506 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Hampton Inn Poplar Bluff
Children's play area - outdoor
Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
8.6 out of 10, Excellent, (334)
"Staff was very friendly."
United States
Joyce
The price is ₩129,948
₩140,879 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Honeysuckle Inn - Mountain View
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
The price is ₩129,948
₩146,583 total
includes taxes & fees
Dec 30 - Dec 31
Drury Inn & Suites Cape Girardeau
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
9.4 out of 10, Exceptional, (142)
"Nice hotel, clean and comfortable "
United States
Laura
The price is ₩130,213
₩146,898 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites by Marriott Cape Girardeau
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
8.4 out of 10, Very Good, (722)
"Room was good as usual. This is 4th stay over past 5 years. Only issue I had on this stay was the orange juice from breakfast options. "
United States
Todd
The price is ₩80,129
₩91,328 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
9.4 out of 10, Exceptional, (477)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is ₩139,060
₩156,878 total
includes taxes & fees
Dec 28 - Dec 29
The Riverview
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is ₩184,961
₩209,587 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Courtyard by Marriott Cape Girardeau Downtown
Fridge, microwave, coffee/tea maker
Shepherd Mountain Inn

Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
9.4 out of 10, Exceptional, (304)
"Everything was wonderful- the family that owns this is very kind, and it’s in a beautiful location!"
United States
Nathan
Shepherd Mountain Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Great stay"
Chris 1-night trip
Posted 1 day ago
Pear Tree Inn Cape Girardeau Near the Medical Center

Find out more about Southeast Missouri

Southeast Missouri Condo Rentals information

Number of reviews
13,172
Accommodation
0 Condo Rentals
Lowest Price
₩91,328
Highest Price
₩242,746

Frequently asked questions

How much do condos in Southeast Missouri cost?
Condos in Southeast Missouri range from ₩91,328 to ₩242,746 per night. These stays provide loads of space for the entire squad at a price that's friendly on the pocket. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many condos are there in Southeast Missouri?
Select from 0 condos in Southeast Missouri. Whether you're on a trip with the fam or a group of pals, and wherever your destination, Expedia makes it a breeze to find the perfect hotel.
Why book your condo in Southeast Missouri with Expedia?
With Expedia, it's easy to find your ideal condo in Southeast Missouri. On the lookout for a luxury stay? Make the most of our filters to search for properties that are 5-star rated. If you have a set budget, select how much you want to spend and then check out our amazing options. We'll help you find the right fit whatever your getaway looks like.
How can I find cheap condos in Southeast Missouri?
Expedia can help you track down cheap condos in Southeast Missouri. To find your special stay in a few quick clicks, use the filter tool to refine your search results by star rating, amenities and budget.
What is there to do in Southeast Missouri near my condo?
There are countless ways to fill your days in Southeast Missouri. If you're heading to Cape Girardeau, stop by Isle Casino Cape Girardeau, Show Me Center and Riverfront Park. Packing your bags for Sikeston? Sikeston Depot Museum, The Book Bug and Central Park are among the top attractions in this city.