A forested valley with autumn foliage, a rocky cliff, and a sunset.

Southern Illinois, Illinois hotel rooms at the Red Lion

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 17 - Aug 18
Tomorrow
Aug 18 - Aug 19
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Our top choices for Southern Illinois Red Lion

1. Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
Granite City
United States
Jennifer
₩101,929
₩115,392 total
includes taxes & fees
Aug 18 - Aug 19
Red Lion Inn & Suites Pontoon Beach

2. Red Lion Inn & Suites Caseyville

Red Lion Inn & Suites Caseyville
Caseyville
United States
Ronald
₩73,261
₩82,718 total
includes taxes & fees
Aug 30 - Aug 31
Red Lion Inn & Suites Caseyville
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Southern Illinois Hotel Reviews

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"Staff member very helpful when i made a small error in my reservation. He gave me the room that i had meant to reserve"
Phil 1-night trip
Posted 1 hour ago
Country Inn & Suites by Radisson, Effingham, IL
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Great stay! Rooms clean and nicer than the typical Holiday Inn Expresses I’m used to. Evening appetizers were heavy appetizers. Highly recommend this hotel."
Amy 1-night trip
Posted 5 hours ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Best hot tub experience and the staff were super friendly and helpful. "
Tara 1-night trip
Posted 13 hours ago
Drury Inn & Suites Marion
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"We enjoyed one night stay there. Brea at the front desk was very helpful and friendly. The hotel was very clean. My room was great. Enjoyed the shower. I was on the second floor was very quiet. The breakfast wasn’t the best. It was OK thanks so much."
Gayla 1-night trip
Posted 21 hours ago
Comfort Suites Mount Vernon
Comfort Suites Fairview Heights - St. Louis

Comfort Suites Fairview Heights - St. Louis

8/10 Good
"The room had a staleness to it, when we first walked in. The ac was set to around 75, so we lowered the temperature and it helped a lot. The carpet was sticky in some places. The room itself seemed run down. The wooden furniture was all scuffed up and scratched. Only one light worked in the bathroom and the vent didn't work. The elevator didn't have the inspection sheet hanging in it. The breakfast reminded my husband of "field chow" from his time in the service. The staff was very friendly and the parking was good."
Danielle 1-night trip
Posted 2 days ago
Comfort Suites Fairview Heights - St. Louis
The Principal Hotel

The Principal Hotel

10/10 Excellent
"The cutest hotel! Friendly staff and the restaurant there has thee best food! Highly recommend!!"
Elmina 1-night trip
Posted 2 days ago
The Principal Hotel
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

8/10 Good
"Room was clean. Staff was friendly. Breakfast was very good."
Gary 1-night trip
Posted 2 days ago
Holiday Inn Express Metropolis by IHG
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

10/10 Excellent
"I had a wonderful experience staying at the Comfort Inn during my daughter’s move-in day at SIUE. The hotel was clean, comfortable, and welcoming from the moment we arrived. The guests were friendly, and the team members were very nice and helpful. I highly recommend the Comfort Inn to anyone visiting the Edwardsville/SIUE area. Thank you to the entire team for making our stay such a pleasant one!"
Lanita 2-night trip
Posted 5 days ago
Comfort Inn Edwardsville - St. Louis

Explore a world of travel with Expedia