Find Gay friendly Hotels in Southpoint, FL

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southpoint Gay friendly Hotels

Our top choices for Southpoint LGBT-friendly hotels

Lobby
Hampton Inn Jacksonville South/I-95 at JTB

Hampton Inn Jacksonville South/I-95 at JTB

Hampton Inn Jacksonville South/I-95 at JTB
2.5 star property
Southside
8.8 out of 10, Excellent, (1004)
"The room was clean and the staff was VERY friendly, highly recommend the hotel."
United States
Frank
The price is ₩149,484
₩169,665 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hampton Inn Jacksonville South/I-95 at JTB
Lobby
Red Roof Inn PLUS+ Jacksonville - Southpoint

Red Roof Inn PLUS+ Jacksonville - Southpoint

Red Roof Inn PLUS+ Jacksonville - Southpoint
2.5 star property
Southside
7.4 out of 10, Good, (1004)
"We stayed for one night on the way from Naples to Charlotte. Clean spacious room with the couch, microwave, fridge, safe. Nice beds. Value for money! "
United States
Olga
The price is ₩94,868
₩107,675 total
includes taxes & fees
Dec 23 - Dec 24
Red Roof Inn PLUS+ Jacksonville - Southpoint
Reception
Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd

Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd

Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd
2.5 star property
Southside
8.8 out of 10, Excellent, (1003)
"The room was clean and staff was very friendly"
United States
DeeAnna
The price is ₩154,785
₩175,681 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Fairfield Inn & Suites by Marriott Jacksonville Butler Blvd
Exterior
Courtyard by Marriott Jacksonville Butler Boulevard

Courtyard by Marriott Jacksonville Butler Boulevard

Courtyard by Marriott Jacksonville Butler Boulevard
3.0 star property
Southside
8.8 out of 10, Excellent, (697)
"Great"
United States
Christopher
The price is ₩154,198
₩175,015 total
includes taxes & fees
Dec 21 - Dec 22
Courtyard by Marriott Jacksonville Butler Boulevard
Exterior
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd

La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
3.0 star property
Southside
6.4 out of 10, (23)
"the breakfast is good lots of choices, room is fine and spacious. "
United States
Rowena
The price is ₩122,125
₩138,612 total
includes taxes & fees
Dec 22 - Dec 23
La Quinta Inn & Suites by Wyndham Jacksonville Butler Blvd
Standard Room, 1 Queen Bed | Premium bedding, pillowtop beds, individually decorated
Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint

Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint

Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint
2.0 star property
Southside
5.0 out of 10, (1004)
"they’re all very nice, get anything you need. will stay again"
United States
Ashley
Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint
Exterior
Towneplace Suites Marriott Jacksonville Butler Boulevard

Towneplace Suites Marriott Jacksonville Butler Boulevard

Towneplace Suites Marriott Jacksonville Butler Boulevard
3.0 star property
Southside
8.0 out of 10, Very Good, (465)
"We enjoyed staying at Towneplace due to location and suite option, and price. "
United States
David
The price is ₩173,509
₩196,932 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Towneplace Suites Marriott Jacksonville Butler Boulevard
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
Jacksonville
9.2 out of 10, Wonderful, (61)
"Beautiful hotel. Close to Mayo Clinic."
United States
Patty
The price is ₩179,427
₩203,650 total
includes taxes & fees
Dec 23 - Dec 24
Hilton Jacksonville At Mayo Clinic
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
Palm Valley
9.0 out of 10, Wonderful, (1017)
"Friendly staff, easy check-in super clean room and facility. Location is excellent as well."
United States
Anthony
The price is ₩168,487
₩187,863 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Exterior
Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
Northside
8.6 out of 10, Excellent, (1000)
"Room was spotless, staff very friendly "
United States
Heidi
The price is ₩133,638
₩151,680 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express Jacksonville - Blount Island by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southpoint Hotel Reviews

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

10/10 Excellent
"This is a lovely hotel. The location is beautiful on the water, the restaurants and staff were awesome, the front desk was helpful and friendly and the rooms are comfortable and clean. The pet situation is great too. There is easy access to a nice grass area for the dogs too. I don’t know how we have missed this on our Jacksonville trips but we will be back! Thank you"
Margaret 1-night trip
Posted 3 days ago
Hyatt Regency Jacksonville

Explore a world of travel with Expedia

Frequently asked questions

Looking for a gay-friendly accommodation in Southpoint?
If you're interested in a place where you'll feel welcome in Southpoint, our website has the LGBTQ-friendly hotel you're looking for. The restaurants is something travelers enjoy about this welcoming area.
What's the best LGBTQ-friendly accommodation in Southpoint?
Red Roof Inn PLUS+ Jacksonville - Southpoint is a top LGBTQ-friendly hotel, and features free WiFi and flat-screen TVs. Courtyard by Marriott Jacksonville Butler Boulevard and Hometown Inn & Suites Jacksonville - Butler Blvd./Southpoint are other good choices for your trip.
How many LGBTQ-friendly hotels are there in Southpoint?
You'll find 7 gay-friendly hotels in Southpoint.
What is there to see in Southpoint?
During your vacation, get out and discover all that Southpoint offers. You and your traveling companions may want to visit St. Johns Town Center.
What is a gay-friendly hotel in Southpoint?
LGBTQ-friendly hotels are places where lesbian, gay, bisexual, and transgender travelers are proudly welcomed. Expedia has compiled a selection of LGBTQ-friendly hotels worldwide. In Southpoint, these hotels will provide lesbian, gay, bisexual, and transgender adventurers with the information needed to design the trip of a lifetime.
What can I expect from a gay-friendly hotel in Southpoint?
Take a vacation from the ordinary; stay at a gay-friendly hotel in Southpoint, and you won't have to hide or your sexuality or your gender identity when you check-in. Some of Expedia's LGBTQ-friendly hotels go the extra mile and offer wedding ceremonies and honeymoon packages for same-sex couples.