Central Missouri Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
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- Better togetherSave up to ₩1,660,000 when you book a flight and hotel together*
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Top Luxury Central Missouri Hotels
Ramada by Wyndham Columbia
901 Conley Rd Columbia MO
- 2 hours drive from Lake of the Ozarks
Ramada by Wyndham Columbia awaits for a deluxe vacation. Popular amenities include an outdoor pool and a fitness center.
voco The Tiger Hotel Columbia, MO by IHG
23 S 8th St Columbia MO
- 2 hours drive from Lake of the Ozarks
Pamper yourself with a luxury stay at voco The Tiger Hotel Columbia, MO by IHG, where you can enjoy amenities like 24-hour room service, pillowtop beds, and ...
9/10 Wonderful! (1,000 reviews)
"When I arrived at the hotel I was a little early for check in after a long early flight the Missouri. I was not able to check in early so was directed to the restaurant where everyone was friendly. Once I was done eating, I went back to the check in and my room still was not ready. I was desperate ..."
Reviewed on Aug 8, 2026
Lodge Of Four Seasons Golf Resort, Marina & Spa
315 Four Seasons Dr. Lake Ozark MO
- 20 min drive from Lake of the Ozarks
Pamper yourself with a luxe vacation at Lodge Of Four Seasons Golf Resort, Marina & Spa. Popular amenities include a spa, a golf course, and 5 bars.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
