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Top Luxury Central Missouri Hotels

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

2 hours drive from Lake of the Ozarks

Ramada by Wyndham Columbia awaits for a deluxe vacation. Popular amenities include an outdoor pool and a fitness center.

7.6/10 Good! (1,010 reviews)

"The facility was very nasty. We even had to change bedrooms because the first room that they gave us was so disgusting. We were definitely not going to stay in end I chose this hotel because it had a pool and the pool you could tell had not been used in a couple years. It was very bad. I do not recommend ..."

Reviewed on Jun 28, 2026

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

2 hours drive from Lake of the Ozarks

Pamper yourself with a luxury stay at voco The Tiger Hotel Columbia, MO by IHG, where you can enjoy amenities like 24-hour room service, pillowtop beds, and ...

9/10 Wonderful! (1,002 reviews)

"Was not clean enough for the price! Instead of a 9.3 star review it should’ve been a 5. They must have bought that 9.3 star review somehow"

Reviewed on Jun 25, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

20 min drive from Lake of the Ozarks

Pamper yourself with a luxe vacation at Lodge Of Four Seasons Golf Resort, Marina & Spa. Popular amenities include a spa, a golf course, and 5 bars.

7.4/10 Good! (1,197 reviews)

"For the amount of money paid, you would think there would be a microwave andrefrigerator in the room. No cleaning service no cell service and spotty Wi-Fi. The shower was terrible hot water to cold water without changing the knob no steady temperature half of the restaurants not open or closed early ..."

Reviewed on Jun 28, 2026

See all 5,159 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.