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Find hotels in Southeast Missouri, MO from ₩84,244
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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,003 reviews)
The price is ₩163,979
₩188,535 total
includes taxes & fees
May 15 - May 16

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (893 reviews)
The price is ₩161,847
₩182,846 total
includes taxes & fees
May 31 - Jun 1

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (177 reviews)
The price is ₩144,338
₩162,834 total
includes taxes & fees
Jun 1 - Jun 2

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,003 reviews)
The price is ₩147,727
₩166,656 total
includes taxes & fees
May 20 - May 21

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
The price is ₩154,491
₩174,288 total
includes taxes & fees
May 17 - May 18

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (829 reviews)
The price is ₩143,162
₩160,300 total
includes taxes & fees
May 31 - Jun 1

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (755 reviews)
The price is ₩144,338
₩156,210 total
includes taxes & fees
May 12 - May 13

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (552 reviews)
The price is ₩155,079
₩175,587 total
includes taxes & fees
May 17 - May 18

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very Good, (989 reviews)
The price is ₩103,803
₩118,829 total
includes taxes & fees
Jun 2 - Jun 3

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (348 reviews)
The price is ₩140,351
₩152,151 total
includes taxes & fees
May 11 - May 12

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,000 reviews)
The price is ₩120,635
₩127,541 total
includes taxes & fees
May 18 - May 19

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (561 reviews)
The price is ₩194,658
₩219,582 total
includes taxes & fees
May 12 - May 13

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (74 reviews)
The price is ₩174,336
₩197,392 total
includes taxes & fees
May 9 - May 10

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very Good, (972 reviews)
The price is ₩136,320
₩155,881 total
includes taxes & fees
May 10 - May 11

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHGFestus
9.4 out of 10, Exceptional, (724 reviews)
The price is ₩179,503
₩205,261 total
includes taxes & fees
May 10 - May 11

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (543 reviews)
The price is ₩139,777
₩158,962 total
includes taxes & fees
May 12 - May 13

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (122 reviews)
The price is ₩143,573
₩163,406 total
includes taxes & fees
May 31 - Jun 1

EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.6 out of 10, Exceptional, (89 reviews)
The price is ₩138,074
₩150,294 total
includes taxes & fees
May 5 - May 6

Super 8 by Wyndham Farmington
Super 8 by Wyndham FarmingtonFarmington
8.0 out of 10, Very Good, (639 reviews)
The price is ₩90,418
₩98,420 total
includes taxes & fees
May 10 - May 11

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (612 reviews)
The price is ₩161,332
₩175,610 total
includes taxes & fees
Jun 1 - Jun 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (64 reviews)
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