Find hotels in Southeast Missouri, MO from ₩77,810

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 3 - Aug 4
Tomorrow
Aug 4 - Aug 5
Next weekend
Aug 8 - Aug 10
In two weeks
Aug 15 - Aug 17

Filter by

Guest rating
Guest rating
Star rating

Compare 588 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins St. Francois
Situated in a wooded area, this cabin features a cozy outdoor space with a porch, bench, fire pit, and table.

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (23)
"Had a wonderful time"
The price is ₩123,663
₩185,388 total
includes taxes & fees
Aug 4 - Aug 5
Postcard Cabins St. Francois
The Farmstead Hotel
Welcome to The Farmstead, where a symmetrical facade and central entrance invite you in.

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (396)
"Great stay!"
The price is ₩118,800
₩135,105 total
includes taxes & fees
Aug 4 - Aug 5
The Farmstead Hotel
Super 8 by Wyndham Farmington
Guests enter through a covered walkway to the hotel's entrance, surrounded by a landscaped area.

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (569)
"Loved it and will be back again. "
The price is ₩82,673
₩94,122 total
includes taxes & fees
Aug 10 - Aug 11
Super 8 by Wyndham Farmington
Drury Inn & Suites Jackson MO
Relax in the hotel's spacious lobby, featuring a comfortable seating area with a sofa, coffee tables, and chairs.

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1004)
"We had a last minute reservation here. The staff was very pleasant, helpful and wonderful overall!!"
The price is ₩125,038
₩132,194 total
includes taxes & fees
Aug 7 - Aug 8
Drury Inn & Suites Jackson MO
Holiday Inn Express & Suites Perryville by IHG
Welcome to our reception area, where guests can check in at the digital station and enjoy the vibrant artwork.

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (493)
"Super nice staff. Our room smelled so nice and clean. Breakfast was very good too! "
The price is ₩152,842
₩174,967 total
includes taxes & fees
Aug 23 - Aug 24
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Indulge in a variety of dishes, including turkey sausage and bacon, at our food section.

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (660)
"Valid to stay at "
The price is ₩163,957
₩187,485 total
includes taxes & fees
Aug 10 - Aug 11
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Super 8 by Wyndham Perryville
Welcome to our hotel, featuring a modern exterior with a covered entrance and inviting outdoor space.

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (887)
"Very clean and rooms might have been renovated last year. "
The price is ₩95,665
₩109,513 total
includes taxes & fees
Sep 1 - Sep 2
Super 8 by Wyndham Perryville
Pear Tree Inn Cape Girardeau West
Welcome to our reception area, featuring a modern reception desk and a cozy seating area with armchairs.

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1002)
"We enjoyed the quick check in and how quiet the property was. "
The price is ₩97,249
₩109,713 total
includes taxes & fees
Aug 4 - Aug 5
Pear Tree Inn Cape Girardeau West
Drury Inn & Suites Hayti Caruthersville
Relax in our spacious lobby with a seating area, fireplace, and stunning views.

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Great stay!"
The price is ₩130,596
₩148,840 total
includes taxes & fees
Aug 10 - Aug 11
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Cape Girardeau
Reception area with a reception desk, flat-screen TV, and seating area.

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (967)
"Love the property. Staff is always amazing."
The price is ₩125,038
₩141,045 total
includes taxes & fees
Aug 7 - Aug 8
Drury Inn & Suites Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Enjoy al fresco dining on the outdoor patio with tables and chairs, surrounded by a metal railing.

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (586)
"This was a great hotel at a great price!"
The price is ₩109,838
₩118,883 total
includes taxes & fees
Sep 1 - Sep 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
Enjoy meals in the dining area with a view, featuring a long counter, TV, and comfortable seating options.

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Excellent place to stay "
The price is ₩97,249
₩109,713 total
includes taxes & fees
Aug 7 - Aug 8
Pear Tree Inn Cape Girardeau Near the Medical Center
Baymont Inn and Suites by Wyndham Farmington, MO
Welcome to our reception area, where guests can check in and relax in a comfortable seating area.

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (1006)
"everything about the hotel was great. some guest were loud at times when trying to sleep but besides that it was a great stay! "
The price is ₩77,810
₩88,587 total
includes taxes & fees
Aug 12 - Aug 13
Baymont Inn and Suites by Wyndham Farmington, MO
Festus Inn
Experience the tranquil atmosphere of this beautifully designed space, featuring a central fountain and lush greenery.

Festus Inn

2.0 star property
5.0 out of 10, (18)
"Quiet property and near plenty of restaurants. Would definitely stay here again. "
The price is ₩127,831
₩146,175 total
includes taxes & fees
Aug 4 - Aug 5
Festus Inn
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Relax in the stylish lobby, featuring a fireplace, comfortable seating, and a large flat-screen TV.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1006)
"Great place to stay. "
The price is ₩137,558
₩155,185 total
includes taxes & fees
Aug 10 - Aug 11
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Comfort Inn Festus - St Louis South
Relax in our inviting lobby, featuring a central seating area, dining tables, and comfortable furniture.

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (846)
"Great Front Desk and easy check in "
The price is ₩107,476
₩125,586 total
includes taxes & fees
Aug 31 - Sep 1
Comfort Inn Festus - St Louis South
The Riverview
Relax in a stylish room with two beds, a desk, and a city view.

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (369)
"A very cool destination!"
The price is ₩146,311
₩165,060 total
includes taxes & fees
Aug 4 - Aug 5
The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center
Relax in a stylish lounge area with a curved sofa, coffee table, and large flat-screen TV.

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1004)
"The staff was very friendly and the hotel was very clean!"
The price is ₩141,712
₩159,872 total
includes taxes & fees
Aug 10 - Aug 11
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO
Relax in the serene courtyard, surrounded by lush greenery and comfortable seating.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1001)
"Will stay again"
The price is ₩125,038
₩143,754 total
includes taxes & fees
Aug 17 - Aug 18
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Relax in our spacious lobby with a large seating area, dining space, and digital cityscape display.

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very Good, (827)
"I was very pleased with our stay here. "
The price is ₩151,174
₩172,867 total
includes taxes & fees
Aug 31 - Sep 1
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:Aug 15 - Aug 17

Image gallery for Tiny Houses of French Village

Cozy living area with a high ceiling, flat-screen TV, and stone fireplace.

Tiny Houses of French Village

2.5 star property
French Village
10/10Exceptional (2 reviews)
10% off
Price is ₩337,641
₩930,994 total
includes taxes & fees
Tiny Houses of French Village
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Top Southeast Missouri Hotel Reviews

The Riverview

The Riverview

10/10 Excellent
"A very cool destination!"
William 1-night trip
Posted 2 days ago
The Riverview