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Find Resorts & Hotels with Spas in Southern Illinois, IL

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Check availability on Southern Illinois Resorts & Hotels with Spas

Tonight
Aug 26 - Aug 27
Tomorrow
Aug 27 - Aug 28
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Our top choices for Southern Illinois hotels with a spa

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
₩173,093
₩192,104 total
includes taxes & fees
Aug 30 - Aug 31
Walker's Bluff Casino Resort
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
Two patterned armchairs, a small round table with a lamp, and a staircase with decorative railings.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
₩140,925
₩158,983 total
includes taxes & fees
Sep 24 - Sep 25
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A two-story house with a front porch, a brick foundation, and a gabled roof.
A porch with two wicker chairs, a potted plant, and a wooden door.
A kitchen with white cabinets, granite countertops, a stainless steel sink, a stove, and a microwave.
A traditional interior with a wooden staircase, a desk with a computer, and a red chair.

3. 1895 Washington Hotel

1895 Washington Hotel
Paducah
  • Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
₩62,845
₩85,025 total
includes taxes & fees
Sep 2 - Sep 3
1895 Washington Hotel

4. Truitt Hotel

Truitt Hotel
Lafayette Square
₩232,112
₩281,767 total
includes taxes & fees
Sep 8 - Sep 9
Truitt Hotel
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
₩229,701
₩291,411 total
includes taxes & fees
Sep 7 - Sep 8
Ameristar Casino Resort and Spa
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A modern lobby with a large glass sphere, seating areas, and a reception desk.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
₩198,760
₩239,326 total
includes taxes & fees
Sep 20 - Sep 21
21C Museum Hotel St Louis
A dining area with a wooden table and chairs, a small Christmas tree, and a window with curtains.
A bedroom with a large bed, a nightstand with a lamp, a chair, and a framed picture on the wall.

7. Arthur's Country Inn

Arthur's Country Inn
Arthur
₩165,794
₩184,004 total
includes taxes & fees
Aug 31 - Sep 1
Arthur's Country Inn
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
₩518,108
₩605,813 total
includes taxes & fees
Sep 6 - Sep 7
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.
A couple standing on a balcony with a cityscape view.

9. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
₩759,618
₩886,788 total
includes taxes & fees
Sep 20 - Sep 21
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"This hotel was fantastic! Very clean! Friendly and helpful staff! The breakfast was delicious and great variety! Definitely recommend this hotel and would stay again!"
Leilani 1-night trip
Posted 13 hours ago
Drury Inn & Suites St. Louis O'Fallon, IL
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

10/10 Excellent
"The breakfast didn't have anything I wanted, but the hotel was clean and quiet."
Roxanne 1-night trip
Posted 13 hours ago
Country Inn & Suites by Radisson, Effingham, IL
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"It had been a long time since I stayed at a Drury Inn, I was very impressed and was cheaper than Comfort inn and Quality Inn and offered more. Like full breakfast and a Happy hour every evening. They have my choice..Thank you so much."
Barbara 2-night trip
Posted 20 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"Great value- Clean room - Amazing staff- Surprisingly good breakfast - Plenty of surrounding food options"
Ollie 2-night trip
Posted 3 days ago
Quality Inn O'Fallon - St. Louis - Shiloh
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Very friendly"
Valerie 2-night trip
Posted 5 days ago
Holiday Inn Express Metropolis by IHG

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