The Best Luxury Hotels in Uptown, OH from ₩137,458 in 2026

A historic building with ornate architecture and a modern brick structure in the foreground.

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Our top choices for Uptown luxury hotels

A spacious hotel lobby with a long corridor, comfortable seating areas, and large windows offering views of the outside.

1. Hilton Cincinnati Airport

Florence

Cincinnati airport hotel offers plush amenities, designer bath products, and concierge service for a refined retreat.

₩178,678 total

includes taxes & fees

Oct 31 - Nov 1

A spiral staircase with a black metal railing and a white wall.

2. 21c Museum Hotel Cincinnati

Downtown Cincinnati

Artful luxury awaits at 21c Museum Hotel Cincinnati, where spa treatments and elevated dining complement the boutique atmosphere.

₩247,610 total

includes taxes & fees

Nov 24 - Nov 25

A rooftop terrace with outdoor seating, overlooking a cityscape with historic buildings and a modern structure.

3. Hotel Covington Cincinnati Riverfront

Central Business District

Riverside luxury meets urban sophistication at this Covington gem with designer rooms and attentive service.

₩296,593 total

includes taxes & fees

Nov 25 - Nov 26

A spacious lobby with a stone fireplace, a chandelier, and a staircase leading to upper floors.

4. DoubleTree by Hilton Cincinnati Airport

Florence

₩239,634 total

includes taxes & fees

Nov 8 - Nov 9

5. The Lytle Park Hotel, Autograph Collection

Downtown Cincinnati

Indulge in rooftop luxury and fine dining at this reimagined Cincinnati retreat steps from Lytle Park.

₩473,326 total

includes taxes & fees

Nov 22 - Nov 23

A modern living room with a fireplace, sofas, armchairs, and a coffee table.

6. The Summit Hotel

Cincinnati

Immerse in art deco luxury at this Cincinnati hotel with rooftop terrace and pillowtop beds.

₩257,364 total

includes taxes & fees

Nov 25 - Nov 26

A cozy lounge area with wooden flooring, cushioned seating, and hanging pendant lights.

7. The Cincinnatian Hotel Curio Collection by Hilton

Downtown Cincinnati

Historic Cincinnati hotel offers indulgent comfort with plush bedding, designer toiletries, and attentive staff.

₩232,346 total

includes taxes & fees

Nov 13 - Nov 14

A modern hotel with a curved facade, large windows, and a well-lit entrance.

8. Doubletree By Hilton Lawrenceburg

Lawrenceburg

₩151,798 total

includes taxes & fees

Nov 23 - Nov 24

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Top Uptown Hotel Reviews

Country Inn & Suites by Radisson, Cincinnati Airport, KY

10/10 Excellent

"This is my go to every time i have a work trip in the hebron area. Close to airport"

The Westin Cincinnati

10/10 Excellent

"It was a pleasant experience. Staff were amazing, amenities were nice, though our stay was brief, we throughly enjoyed it. One of the best hotels I’ve stayed in. The only issue was though we had to pay to park which is fine, the fact that each time we left the parking area we had to pay each time. We realized we need to use ride share services the next time in visiting this establishment. Otherwise, would love to revisit!"

Renaissance Cincinnati Downtown Hotel

8/10 Good

"Nice hotel in a central location. Parking (valet) is $50/day with in and out privileges. On the day I left, instead of pulling into one of the spaces open at the curb, the valet opted instead to throw on my car’s hazards in the middle of 4th Street, backing up traffic. He also failed to put my car into park before he got out so it started drifting away. When people on the sidewalk (including me) started yelling, he jumped back in and managed to put it in park, still blocking the street but at least it didn’t crash. I loaded the back and drove off. Although I’m guessing the valet is an independent contractor and not a hotel employee, I’m deducting a star for the experience. Absolutely wild - but glad nobody was hurt. The hotel itself is fine."

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Treat yourself

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Check availability on Uptown Luxury Hotels

Our top choices for Uptown luxury hotels

1. Hilton Cincinnati Airport

2. 21c Museum Hotel Cincinnati

3. Hotel Covington Cincinnati Riverfront

4. DoubleTree by Hilton Cincinnati Airport

5. The Lytle Park Hotel, Autograph Collection

6. The Summit Hotel

7. The Cincinnatian Hotel Curio Collection by Hilton

8. Doubletree By Hilton Lawrenceburg

9. TownePlace Suites by Marriott Cincinnati Mason

10. Walk to Bellevue Hot Tub 4BR Historic Home

Top Uptown Hotel Reviews

Country Inn & Suites by Radisson, Cincinnati Airport, KY

The Westin Cincinnati

21c Museum Hotel Cincinnati

Renaissance Cincinnati Downtown Hotel

Hotel Covington Cincinnati Riverfront

Ashley Quarters Hotel Cincinnati Airport

Explore a world of travel with Expedia

Find Luxury Hotels in Uptown, OH

Change your mind

Treat yourself

Be picky

Check availability on Uptown Luxury Hotels

Our top choices for Uptown luxury hotels

1. Hilton Cincinnati Airport

2. 21c Museum Hotel Cincinnati

3. Hotel Covington Cincinnati Riverfront

4. DoubleTree by Hilton Cincinnati Airport

5. The Lytle Park Hotel, Autograph Collection

6. The Summit Hotel

7. The Cincinnatian Hotel Curio Collection by Hilton

8. Doubletree By Hilton Lawrenceburg

9. TownePlace Suites by Marriott Cincinnati Mason

10. Walk to Bellevue Hot Tub 4BR Historic Home

Top Uptown Hotel Reviews

Country Inn & Suites by Radisson, Cincinnati Airport, KY

Explore a world of travel with Expedia