Find hotels in Downtown South San Francisco, San Francisco

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Our top choices for Downtown South San Francisco hotels

Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2015)
"Clean room, staff were friendly, breakfast was good, parking was good, overall we're satisfied!"
Canada
Edna
The price is ₩145,619
₩171,057 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Interior detail
Airport Inn

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (972)
"Very clean room, friendly staff and secure parking."
United States
Christopher
The price is ₩142,523
₩167,141 total
includes taxes & fees
Jan 18 - Jan 19
Airport Inn
Fridge, microwave, coffee/tea maker, dining tables
Miller Apartments

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.4 out of 10, Good, (15)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is ₩107,972
₩234,876 total
includes taxes & fees
Jan 5 - Jan 6
Miller Apartments
Lobby
Inn By The SFO

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
United States
David
Inn By The SFO
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7222)
"Great place to stay!"
United States
Isaiah
The price is ₩143,990
₩228,987 total
includes taxes & fees
Jan 5 - Jan 6
Hotel Riu Plaza Fisherman's Wharf
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
16.7 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (3842)
"Excellent stay and great location! "
United States
CHRISTINE
The price is ₩175,716
₩273,116 total
includes taxes & fees
Jan 30 - Jan 31
Hotel Caza Fisherman's Wharf
Exterior
The Westin San Francisco Airport

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.8 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2021)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is ₩148,167
₩212,450 total
includes taxes & fees
Jan 17 - Jan 18
The Westin San Francisco Airport
Front of property - evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
15.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2214)
"We loved our stay! "
United States
Christine
The price is ₩129,120
₩151,968 total
includes taxes & fees
Jan 8 - Jan 9
Hilton San Francisco Financial District
Breakfast served, American cuisine
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
9.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2796)
"Very nice hotel"
United States
TingTing
The price is ₩150,988
₩171,666 total
includes taxes & fees
Jan 3 - Jan 4
Hilton San Francisco Airport Bayfront
Exterior
Aloft San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2231)
"Room was clean and comfortable"
United States
Tammie L
The price is ₩162,722
₩187,041 total
includes taxes & fees
Jan 2 - Jan 3
Aloft San Francisco Airport
Breakfast, lunch, dinner served; local cuisine
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
9.3 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1399)
"Great location and staff"
United States
Ernest Dean
The price is ₩164,463
₩186,987 total
includes taxes & fees
Jan 17 - Jan 18
DoubleTree by Hilton San Francisco Airport
Lobby
Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport

Best Western Inn & Suites San Mateo - San Francisco Airport
2.5 star property
11.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1257)
"Good place to stay, clean and good breakfast."
United States
Xiaohong
The price is ₩136,031
₩156,360 total
includes taxes & fees
Jan 4 - Jan 5
Best Western Inn & Suites San Mateo - San Francisco Airport
Interior entrance
Hotel Aura SFO

Hotel Aura SFO

Hotel Aura SFO
3.0 star property
4.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2555)
"Clean, quiet, close to the airport."
United States
RICHARD
The price is ₩136,516
₩163,876 total
includes taxes & fees
Jan 23 - Jan 24
Hotel Aura SFO
Game room
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
16.8 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2348)
"Great location"
United States
Deborah
The price is ₩180,808
₩263,813 total
includes taxes & fees
Jan 5 - Jan 6
Hotel Zephyr San Francisco
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
14.7 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (3118)
"Location, ease of check in, great staff"
United States
Margaret
The price is ₩109,037
₩128,838 total
includes taxes & fees
Jan 4 - Jan 5
Chancellor Hotel on Union Square
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
15.4 km from Downtown South San Francisco
8.8 out of 10, Excellent, (2844)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is ₩144,366
₩169,912 total
includes taxes & fees
Jan 4 - Jan 5
Club Quarters Hotel in San Francisco
Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
14.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (5068)
"Great location, friendly staff and all the amenities. "
United States
Kerry
The price is ₩171,910
₩202,334 total
includes taxes & fees
Jan 4 - Jan 5
Holiday Inn Golden Gateway by IHG
Front of property - evening/night
Hotel Nikko San Francisco

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
14.3 km from Downtown South San Francisco
9.4 out of 10, Exceptional, (2662)
"Great service, great location, great hotel. "
United States
Laura
The price is ₩219,040
₩323,989 total
includes taxes & fees
Jan 24 - Jan 25
Hotel Nikko San Francisco
Exterior
Half Moon Bay Lodge

Half Moon Bay Lodge

Half Moon Bay Lodge
3.0 star property
24.9 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (1092)
"Always great staff here, nice rooms, nice jacuzzi "
United States
Pamela
The price is ₩207,955
₩243,993 total
includes taxes & fees
Jan 7 - Jan 8
Half Moon Bay Lodge
Free daily buffet breakfast
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
16.6 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (2252)
"Awesome place to stay"
United States
Mark Anthony
The price is ₩171,910
₩249,279 total
includes taxes & fees
Jan 4 - Jan 5
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Union Square which includes a high rise building and a city

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco featuring railway items

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman\'s Wharf featuring a bay or harbor

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market featuring skyline, a city and city views

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

10/10 Excellent
"it was all very good"
Jun Ho 1-night trip
Posted 15 hours ago
Hilton San Francisco Airport Bayfront

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.
What's a favorite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Another favorite option in the neighborhood is Airport Inn.
How many hotels will I find in the Downtown South San Francisco area?
When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 14 Expedia hotels and other accommodations in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.
Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?
To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.
What can I see and do in this South San Francisco neighborhood?
See's Candies, Cinemark Century at Tanforan, and K1 Speed are just a few of the places to visit in and around Downtown South San Francisco. K1 Speed San Francisco and The Shops at Tanforan are also worth a visit when you're out sightseeing in South San Francisco.