Destination Hotels Hotels: Book Destination Hotels Hotel Rooms & Suites in James Island, Charleston

A lighthouse on a pier extending into a calm body of water.

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Our top choices for James Island Destination Hotels

A resort with multiple swimming pools, lounge areas, and a fire pit.

A private cabana with a wicker sofa, a glass table with a tray of food, and a view of greenery through a lattice window.

A resort with multiple buildings, two swimming pools, and a beach area with sun loungers.

A golf course with bunkers, a sand trap, and a building in the background.

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Isle of Palms

Michelle

₩226,908

₩306,190 total

includes taxes & fees

Nov 15 - Nov 16

A beachfront hotel with a pool, beach access, and a sunset view.

A coastal hotel with multiple buildings, a beach in the background, and surrounding greenery.

A balcony with a view of the ocean, furnished with yellow chairs and a table, and decorated with flowers and candles.

A spacious living area with a sofa, coffee table, and dining table. A kitchen with granite countertops and wooden cabinets is visible.

2. Wild Dunes Resort – Residences at Sweetgrass

Isle of Palms

Jeff

₩280,614

₩377,204 total

includes taxes & fees

Nov 15 - Nov 16

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Top James Island Hotel Reviews

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent

"Great location staff was amazing. Rooms are spacious!!"

The Francis Marion Hotel

10/10 Excellent

"Breakfast was not provided, but the restaurant had great options!"

The Vendue

10/10 Excellent

"We absolutely loved everything about The Vendue: fabulous artwork, wonderful staff and concierge service, the location is supreme and safe at night, walked to 5 star restaurants, and one of the best perks is their warm homemade chocolate chip cookies and milk after a long day and dinner. They were dangerous in the best way! We had a king room with windows. We would stay there again in a heartbeat. Thanks to the wonderful staff for making our visit so memorable."

Harborside at Charleston Harbor Resort and Marina

8/10 Good

"All was great except for toilet not flushing well"

Cambria Hotel Mount Pleasant – Charleston

10/10 Excellent

"We had a clean room, clean sheets and towels, with a small fridge and microwave in the room. Downstairs in the lobby was a small "store" with drinks and food that we could purchase and use in our room. Since it rained we didn't use the pool, but used the gym and the staff was friendly and helpful with ideas of other things we could do because of the rain. Their bar was fairly well stocked...It was a pleasant experience, just what we needed!"