A rustic wooden interior with a table, a basket, and a painting on easels.

James Island, Charleston hotel rooms at the Independent

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Sep 12 - Sep 13
Tomorrow
Sep 13 - Sep 14
Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27
Save an average of 15% on thousands of hotels when you're signed in

Top James Island Hotel Reviews

Embassy Suites by Hilton Charleston Historic District

Embassy Suites by Hilton Charleston Historic District

10/10 Excellent
"All the staff were friendly and helpful. The breakfast buffet and made to order omelettes were very good. The location was very convenient for our sight seeing and activities. We would definitely stay here again."
Brenda R 3-night trip
Posted 2 hours ago
Embassy Suites by Hilton Charleston Historic District
Drury Plaza Hotel North Charleston

Drury Plaza Hotel North Charleston

10/10 Excellent
"Our stay was great! Room was clean and comfortable. The food offerings were pretty good. The pool and hot tub were a welcome surprise and we were happy we were able to take advantage of it. We just wish there were Drury Plaza Hotels closer to home for when we take short weekend trips."
Orell 3-night trip
Posted 2 hours ago
Drury Plaza Hotel North Charleston
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

8/10 Good
"A lovely, 4 star rating. Staff is friendly, towels could be newer."
Nancy 3-night trip
Posted 2 hours ago
The Beach Club at Charleston Harbor Resort and Marina
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

8/10 Good
"Nice hotel, the staff is kind, room is clean, room design is nice. Parking is good. Restaurant around is good. Generally saying it is a nice hotel to stay if you rent a car to visit Charleston."
LINLIN 3-night trip
Posted 3 hours ago
Cambria Hotel Mount Pleasant – Charleston
The Ryder Hotel

The Ryder Hotel

8/10 Good
"X"
Stephanie 2-night trip
Posted 4 hours ago
The Ryder Hotel
Quality Inn Mt. Pleasant - Charleston

Quality Inn Mt. Pleasant - Charleston

10/10 Excellent
"My room was clean and very nice. Breakfast was also very good. It was fresh and hot. Only thing that may be an issue for someone else is there is no elevator but there are only 2 floors. My stay was wonderful."
NyAsia 2-night trip
Posted 14 hours ago
Quality Inn Mt. Pleasant - Charleston
Tides Folly Beach, Charleston's Oceanfront Hotel

Tides Folly Beach, Charleston's Oceanfront Hotel

8/10 Good
"The beach view is beautiful!"
Emely 1-night trip
Posted 15 hours ago
Tides Folly Beach, Charleston's Oceanfront Hotel

Explore a world of travel with Expedia