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Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

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Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

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Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

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South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

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Top Mission Bay Hotel Reviews

Chancellor Hotel on Union Square

10/10 Excellent

"Loved this place great customer service and the room was amazing. "

Holiday Inn Golden Gateway by IHG

10/10 Excellent

"The hotel here was very lovely and 26th floor had such a beautiful city view. Clean room, kind staff, and great amenities here. The only thing they do not have is a microwave in the room, but there is a restaurant on site and a mini cafe. Along with that, great restaurants around walking distance wise. :)"

Handlery Union Square Hotel

10/10 Excellent

"Checking in and out was easy. Staff friendly and helpful. Handlery is in the heart of Union Square and within walking distance to restaurants, stores, the theater and Chinatown. When I’m in the city I always choose the Handlery. My only complaint would be having a discounted rate for parking if you are guests at the hotel. We parked in another garage that was considerably cheaper. "

Frequently asked questions

What is Mission Bay like?

Travelers will be sure to enjoy their time in San Francisco's Mission Bay neighborhood. Be sure to check out Chase Center and Lefty O'Doul Bridge as part of your Mission Bay travel plans.

Where is the best place to stay in Mission Bay?

Based on Expedia customer reviews, LUMA Hotel San Francisco is the highest ranked property in Mission Bay. This hotel is a short 5-minute walk from Oracle Park, and it offers a restaurant and a fitness center.

How many hotels are there in Mission Bay?

When you want to kick up your feet after a day of exploring the sights in San Francisco, you can choose from 18 Expedia hotels and other accommodations in Mission Bay.

If I need to cancel my hotel reservation in Mission Bay, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then filter by "fully refundable" to get the best deals in Mission Bay.

Where can I learn more about changing or cancelling my trip to Mission Bay?

To access more information about changing or cancelling your trip to Mission Bay, head over to our customer service page.

What are the top things to see and do in Mission Bay?

Chase Center, Lefty O'Doul Bridge, and Lucky Strike San Francisco are just a few attractions to check out in Mission Bay. While you're out sightseeing, Oracle Park and Pier 39 are a couple of additional sights to visit in San Francisco.

How can I get around Mission Bay and the greater San Francisco area?

For a quick way to explore the city, catch a ride on metro transit at UCSF/Chase Center Stop, Mission Rock Station, or UCSF Mission Bay Stop. To venture out of town, take a train from San Francisco Station.

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Our top choices for Mission Bay hotels

LUMA Hotel San Francisco

Hotel Riu Plaza Fisherman's Wharf

Hilton San Francisco Financial District

Handlery Union Square Hotel

Hotel Caza Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

King George Hotel

Hotel Zephyr San Francisco

YOTEL San Francisco

Holiday Inn Golden Gateway by IHG

Club Quarters Hotel in San Francisco

DoubleTree by Hilton San Francisco Airport North Bayfront

Chancellor Hotel on Union Square

Hotel Nikko San Francisco

The Westin San Francisco Airport

Stanford Court San Francisco

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Hotel Shattuck Plaza

Hilton San Francisco Airport Bayfront

FOUND Hotel, San Francisco

Where to stay in Mission Bay

Union Square

Downtown San Francisco

Fisherman's Wharf

South of Market

Nob Hill

Top Mission Bay Hotel Reviews

Chancellor Hotel on Union Square

Frequently asked questions

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