Find hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,855 reviews)
"Happy with are stay"
Yaril
The price is ₩192,630
₩219,117 total
includes taxes & fees
Aug 24 - Aug 25
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,015 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩148,907
₩169,381 total
includes taxes & fees
Sep 20 - Sep 21
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,086 reviews)
"Love it! Amazing stay! Will book again for our next trip."
Evelyn
The price is ₩230,048
₩253,496 total
includes taxes & fees
Sep 6 - Sep 7
4. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,051 reviews)
"Great stay!"
Samuel
The price is ₩198,326
₩218,545 total
includes taxes & fees
Sep 7 - Sep 8
5. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,652 reviews)
"Great hotel to stay."
Katsuya
The price is ₩155,282
₩171,122 total
includes taxes & fees
Sep 7 - Sep 8
6. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,377 reviews)
"Great stay"
Luis
The price is ₩157,319
₩178,950 total
includes taxes & fees
Sep 13 - Sep 14
7. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,457 reviews)
"Good breakfast, friendly staff and great housekeeping."
Jose
The price is ₩189,651
₩208,616 total
includes taxes & fees
Sep 7 - Sep 8
8. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,731 reviews)
"great STAFF , always helpful , friendly , great place to stay"
Luis
The price is ₩147,244
₩161,968 total
includes taxes & fees
Sep 1 - Sep 2
9. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,710 reviews)
"Very happy with the overall stay. Very efficient procedure from check in to check out."
Ivan
The price is ₩223,756
₩257,196 total
includes taxes & fees
Aug 30 - Aug 31
10. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,223 reviews)
"Just a great place to stay!"
Tracy
The price is ₩154,947
₩191,675 total
includes taxes & fees
Sep 22 - Sep 23
11. SureStay Hotel by Best Western Chula Vista San Diego Bay
SureStay Hotel by Best Western Chula Vista San Diego Bay14.7 km from Otay Mesa
8.0 out of 10, Very Good, (1,860 reviews)
"The hotel and stay was excellent, much more than I expected."
Victor
The price is ₩111,019
₩122,337 total
includes taxes & fees
Aug 30 - Aug 31
12. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.6 out of 10, Excellent, (3,671 reviews)
"Very close to most restaurants and activities 💪👌"
Morne De
The price is ₩210,646
₩312,221 total
includes taxes & fees
Sep 2 - Sep 3
13. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,498 reviews)
"Great hotel,"
Keane
The price is ₩118,690
₩130,791 total
includes taxes & fees
Sep 8 - Sep 9
14. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,109 reviews)
"The golf courses and hotel were great!"
Tom
The price is ₩171,981
₩205,809 total
includes taxes & fees
Aug 24 - Aug 25
15. Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.4 out of 10, Good, (2,301 reviews)
"Nice staff and close to everything"
Suksan
The price is ₩98,222
₩108,044 total
includes taxes & fees
Sep 21 - Sep 22
16. Kings Inn San Diego
Kings Inn San Diego29.1 km from Otay Mesa
8.8 out of 10, Excellent, (3,756 reviews)
"Great place to stay"
Manuel
The price is ₩134,827
₩154,714 total
includes taxes & fees
Aug 24 - Aug 25
17. Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,096 reviews)
"Very good hotel at the price with good choice of breakfast."
Tirthankar
The price is ₩195,402
₩224,605 total
includes taxes & fees
Aug 30 - Aug 31
18. Best Western Plus Hacienda Hotel Old Town
Best Western Plus Hacienda Hotel Old TownOld Town San Diego, 29.9 km from Otay Mesa
8.4 out of 10, Very Good, (2,107 reviews)
"This is a beautiful hotel in a great location."
Robert
The price is ₩185,854
₩213,629 total
includes taxes & fees
Aug 30 - Aug 31
19. Hampton Inn & Suites Imperial Beach San Diego
Hampton Inn & Suites Imperial Beach San Diego13.7 km from Otay Mesa
9.4 out of 10, Exceptional, (1,005 reviews)
"Great service and friendly service staff"
Jose
The price is ₩192,048
₩219,309 total
includes taxes & fees
Aug 30 - Aug 31
20. Homewood Suites by Hilton San Diego Airport/Liberty Station
Homewood Suites by Hilton San Diego Airport/Liberty Station29.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,680 reviews)
"Great place to stay second time going."
Sergio
The price is ₩253,413
₩291,286 total
includes taxes & fees
Aug 31 - Sep 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Top Otay Mesa Hotel Reviews
Gaylord Pacific Resort & Convention Center
10/10 Excellent
