Find hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,855 reviews)
"Good hotel for the area, can’t go wrong with a holiday inn express."
Kuljit
The price is ₩188,341
₩214,239 total
includes taxes & fees
Oct 1 - Oct 2
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,004 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩146,333
₩166,453 total
includes taxes & fees
Sep 7 - Sep 8
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,071 reviews)
"We love this hotel: all the staff are very nice and helpful."
Shan Shan
The price is ₩240,031
₩264,502 total
includes taxes & fees
Sep 20 - Sep 21
4. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,068 reviews)
"Great stay!"
Samuel
The price is ₩203,772
₩224,546 total
includes taxes & fees
Sep 7 - Sep 8
5. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,648 reviews)
"Great hotel to stay."
Katsuya
The price is ₩146,370
₩161,300 total
includes taxes & fees
Sep 9 - Sep 10
6. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,365 reviews)
"Great stay"
Luis
The price is ₩156,062
₩177,520 total
includes taxes & fees
Sep 20 - Sep 21
7. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,495 reviews)
"Enjoyed my stay"
Cathie
The price is ₩208,080
₩228,895 total
includes taxes & fees
Sep 7 - Sep 8
8. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,726 reviews)
"Great amenities, clean rooms, staff is extremely helpful."
Sharon
The price is ₩146,067
₩160,673 total
includes taxes & fees
Sep 13 - Sep 14
9. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,708 reviews)
"Loved the staff and location."
David
The price is ₩255,823
₩294,047 total
includes taxes & fees
Sep 7 - Sep 8
10. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,201 reviews)
"Just a great place to stay!"
Tracy
The price is ₩146,492
₩181,217 total
includes taxes & fees
Oct 1 - Oct 2
11. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,500 reviews)
"The room was clean, and the staff was very helpful"
Mahmoud
The price is ₩135,338
₩149,136 total
includes taxes & fees
Sep 29 - Sep 30
12. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.6 out of 10, Excellent, (3,666 reviews)
"Lovely resort with great food and great location . Good for a relaxing getaway ."
Pooja
The price is ₩207,875
₩308,115 total
includes taxes & fees
Sep 7 - Sep 8
13. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (759 reviews)
"Nice hotel"
Alfonso
The price is ₩270,743
₩298,346 total
includes taxes & fees
Sep 27 - Sep 28
14. Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.4 out of 10, Good, (2,303 reviews)
"Great place to stay and very convenient"
Idanesha
The price is ₩93,593
₩102,952 total
includes taxes & fees
Sep 3 - Sep 4
15. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,137 reviews)
"The golf courses and hotel were great!"
Tom
The price is ₩149,752
₩181,138 total
includes taxes & fees
Sep 9 - Sep 10
16. WoodSpring Suites Santee - San Diego Northeast
WoodSpring Suites Santee - San Diego Northeast30.9 km from Otay Mesa
8.6 out of 10, Excellent, (237 reviews)
"Great place to stay"
Adan
The price is ₩129,227
₩142,150 total
includes taxes & fees
Sep 3 - Sep 4
17. Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,092 reviews)
"Very good hotel at the price with good choice of breakfast."
Tirthankar
The price is ₩213,086
₩244,931 total
includes taxes & fees
Sep 13 - Sep 14
18. Best Western Seven Seas
Best Western Seven Seas28.7 km from Otay Mesa
8.0 out of 10, Very Good, (3,851 reviews)
"This is a nice hotel - not fancy rooms but clean and good A/C and pool!"
Colleen
The price is ₩115,699
₩132,991 total
includes taxes & fees
Sep 3 - Sep 4
19. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,426 reviews)
"Great stay"
Bernadette
The price is ₩184,079
₩207,546 total
includes taxes & fees
Sep 8 - Sep 9
20. Four Points by Sheraton San Diego
Four Points by Sheraton San Diego32.4 km from Otay Mesa
8.2 out of 10, Very Good, (1,000 reviews)
"The place was nice"
Stacey
The price is ₩184,626
₩212,218 total
includes taxes & fees
Sep 7 - Sep 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
