What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on our traveler data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/ .

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Top Otay Mesa Hotels

A city skyline with high-rise buildings and a bridge over a body of water.

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Our top choices for Otay Mesa hotels

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

Kuljit

₩208,939 total

includes taxes & fees

Oct 8 - Oct 9

A breakfast station with bread, bagels, waffles, and a coffee machine.

2. Quality Suites San Diego Otay Mesa

Otay Mesa

Mia

₩162,348 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with a large bed, a desk, a chair, a painting, and a view of the city.

3. Best Western Plus Marina Gateway Hotel

16.9 km from Otay Mesa

Alexander

₩205,362 total

includes taxes & fees

Sep 10 - Sep 11

An outdoor patio area with seating and a bar.

4. Ayres Hotel San Diego South - Chula Vista

6.5 km from Otay Mesa

Shan Shan

₩287,216 total

includes taxes & fees

Oct 1 - Oct 2

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

5. Best Western Americana Inn

8 km from Otay Mesa

Luis

₩173,130 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

6. Comfort Inn Chula Vista San Diego South

13 km from Otay Mesa

Katsuya

₩161,964 total

includes taxes & fees

Sep 20 - Sep 21

A Holiday Inn Express building with a prominent entrance, palm trees, and a clear sky.

7. Holiday Inn Express San Diego South - Chula Vista by IHG

14.5 km from Otay Mesa

Cathie

₩201,390 total

includes taxes & fees

Sep 10 - Sep 11

A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

8. La Quinta Inn by Wyndham San Diego Chula Vista

12.9 km from Otay Mesa

Sharon

₩152,954 total

includes taxes & fees

Sep 20 - Sep 21

A retro-themed arcade with classic games, a foosball table, and a long communal table with stools.

9. The Rambler Hotel

14.8 km from Otay Mesa

Tracy

₩177,249 total

includes taxes & fees

Oct 7 - Oct 8

A modern hotel with a prominent 'Hercor Hotel' sign, multiple balconies, and a 'Urban Boutique' label.

10. Hercor Hotel - Urban Boutique

13.6 km from Otay Mesa

Mahmoud

₩146,208 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with two beds, a desk, and a chair.

11. Howard Johnson by Wyndham National City/San Diego South

18.3 km from Otay Mesa

Erika

₩113,426 total

includes taxes & fees

Oct 1 - Oct 2

A spacious lobby with a large seating area, a wooden ceiling, and large windows offering a view of the outdoor patio area.

12. Hampton Inn & Suites San Diego Airport Liberty Station

29.2 km from Otay Mesa

David

₩271,407 total

includes taxes & fees

Oct 5 - Oct 6

A balcony with wicker furniture overlooking a marina and a coastal cityscape.

13. Sheraton San Diego Resort

28.1 km from Otay Mesa

Kathleen

₩329,428 total

includes taxes & fees

Sep 27 - Sep 28

14. SpringHill Suites by Marriott Chula Vista Eastlake

10.5 km from Otay Mesa

Alfonso

₩290,967 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a bed, a desk with a chair, a nightstand, and a wall-mounted TV displaying a sunset scene.

15. Hotel Palmeras Chula Vista

14.4 km from Otay Mesa

Idanesha

₩104,529 total

includes taxes & fees

Oct 8 - Oct 9

A hotel lobby with a 'Lobby' sign, palm trees, and a sunset sky.

16. Best Western Seven Seas

28.7 km from Otay Mesa

Daijanice

₩130,379 total

includes taxes & fees

Sep 10 - Sep 11

A modern hotel room with a large bed, bedside tables, a desk, and a wardrobe.

17. Holiday Inn Express San Diego Airport - Old Town by IHG

28.8 km from Otay Mesa

Faleoalii Iereneo

₩217,299 total

includes taxes & fees

Sep 23 - Sep 24

A multi-story hotel with a prominent entrance, a stone facade, and a clear sky.

18. WoodSpring Suites Santee - San Diego Northeast

30.9 km from Otay Mesa

Adan

₩131,260 total

includes taxes & fees

Sep 10 - Sep 11

A swimming pool with palm trees and a mountain in the background.

19. Sycuan Casino Resort

28.5 km from Otay Mesa

Tom

₩145,505 total

includes taxes & fees

Oct 5 - Oct 6

A spacious living room with a large arched window, a red sofa, a coffee table, and a chandelier.

20. Lamplighter Inn & Suites at SDSU

24.4 km from Otay Mesa

Bernadette

₩198,391 total

includes taxes & fees

Oct 7 - Oct 8

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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

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A pier at sunset with people sitting and standing, waves crashing below.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

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Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

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A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

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A beach with palm trees, a hotel, and people enjoying the sand and water.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

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Top Otay Mesa Hotel Reviews

Omni San Diego Hotel at the Ballpark

8/10 Good

"Excellent staff!! Access to ballpark rocked!! Need to update rooms bathroom!! Thx u!! Will be back!!!"

The Sofia Hotel

10/10 Excellent

"We had a wonderful stay at The Sofia Hotel! The hotel has so much charm and character, and the location was incredibly convenient for everything we wanted to do in San Diego. One thing that really stood out to us was the housekeeping. Our room was refreshed and tidied up every single day, which is something you just don’t find very often anymore! It was such a nice feeling coming back after a long day to a clean, refreshed room and a neatly made bed. Those little touches really made our stay feel special. The staff was friendly and helpful throughout our stay, and overall we had a great experience. We would absolutely stay at The Sofia again on another trip to San Diego!"

Hard Rock Hotel San Diego

10/10 Excellent

"It’s a fun well located super clean hotel with great entertainment and proximity to the fun gas lamp and Padres field. Pool is small a somewhat lame - but expected for a rooftop. Our coffee machine was malfunctioning but again… we could have asked for a replacement and that’s on us."

Paradise Point Resort & Spa

8/10 Good

"This hotel is very central and a good base. The room was clean and a good size. Moving around the property is a good way to make your step mark. Dining options are limited to 2 restaurants on premises and a market. Will recommend to bring your own snacks and water if you have a large group. Has a marina in place and you have multiple rental options. The views of the cove are great"

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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2. Quality Suites San Diego Otay Mesa

3. Best Western Plus Marina Gateway Hotel

4. Ayres Hotel San Diego South - Chula Vista

5. Best Western Americana Inn

6. Comfort Inn Chula Vista San Diego South

7. Holiday Inn Express San Diego South - Chula Vista by IHG

8. La Quinta Inn by Wyndham San Diego Chula Vista

9. The Rambler Hotel

10. Hercor Hotel - Urban Boutique

11. Howard Johnson by Wyndham National City/San Diego South

12. Hampton Inn & Suites San Diego Airport Liberty Station

13. Sheraton San Diego Resort

14. SpringHill Suites by Marriott Chula Vista Eastlake

15. Hotel Palmeras Chula Vista

16. Best Western Seven Seas

17. Holiday Inn Express San Diego Airport - Old Town by IHG

18. WoodSpring Suites Santee - San Diego Northeast

19. Sycuan Casino Resort

20. Lamplighter Inn & Suites at SDSU

Where to stay in Otay Mesa

Downtown San Diego

Pacific Beach

Gaslamp Quarter

Mission Beach

Ocean Beach

Top Otay Mesa Hotel Reviews

Omni San Diego Hotel at the Ballpark

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