Find hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,858 reviews)
"Good hotel for the area, can’t go wrong with a holiday inn express."
Kuljit
The price is ₩184,421
₩209,779 total
includes taxes & fees
Oct 5 - Oct 6
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,005 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩143,431
₩163,153 total
includes taxes & fees
Sep 13 - Sep 14
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,073 reviews)
"We love this hotel: all the staff are very nice and helpful."
Shan Shan
The price is ₩235,036
₩258,997 total
includes taxes & fees
Sep 20 - Sep 21
4. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,087 reviews)
"Great stay!"
Samuel
The price is ₩200,575
₩221,023 total
includes taxes & fees
Sep 7 - Sep 8
5. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,368 reviews)
"Great stay"
Luis
The price is ₩152,814
₩173,826 total
includes taxes & fees
Sep 27 - Sep 28
6. Baymont by Wyndham San Diego Downtown
Baymont by Wyndham San Diego Downtown24.8 km from Otay Mesa
7.4 out of 10, Good, (1,001 reviews)
"Lovely stay ,very clean"
jacqueline
The price is ₩133,268
₩151,845 total
includes taxes & fees
Sep 8 - Sep 9
7. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,141 reviews)
"The golf courses and hotel were great!"
Tom
The price is ₩118,123
₩146,090 total
includes taxes & fees
Oct 6 - Oct 7
8. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,652 reviews)
"Great hotel to stay."
Katsuya
The price is ₩147,322
₩162,349 total
includes taxes & fees
Oct 4 - Oct 5
9. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,503 reviews)
"Enjoyed my stay"
Cathie
The price is ₩193,373
₩212,717 total
includes taxes & fees
Sep 7 - Sep 8
10. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,729 reviews)
"Great amenities, clean rooms, staff is extremely helpful."
Sharon
The price is ₩141,883
₩156,071 total
includes taxes & fees
Sep 20 - Sep 21
11. WoodSpring Suites Santee - San Diego Northeast
WoodSpring Suites Santee - San Diego Northeast30.9 km from Otay Mesa
8.6 out of 10, Excellent, (238 reviews)
"Great place to stay"
Adan
The price is ₩133,268
₩146,594 total
includes taxes & fees
Sep 6 - Sep 7
12. Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,753 reviews)
"Decent and clean stay for the price"
Melissa
The price is ₩93,484
₩107,121 total
includes taxes & fees
Sep 23 - Sep 24
13. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (763 reviews)
"Nice hotel"
Alfonso
The price is ₩265,109
₩292,137 total
includes taxes & fees
Sep 27 - Sep 28
14. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,206 reviews)
"Just a great place to stay!"
Tracy
The price is ₩159,310
₩197,076 total
includes taxes & fees
Sep 22 - Sep 23
15. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,505 reviews)
"The room was clean, and the staff was very helpful"
Mahmoud
The price is ₩133,214
₩146,796 total
includes taxes & fees
Sep 21 - Sep 22
16. Courtyard by Marriott San Diego El Cajon
Courtyard by Marriott San Diego El Cajon26.3 km from Otay Mesa
9.2 out of 10, Wonderful, (1,000 reviews)
"Updated property, helpful staff, close to quality restaurants. Parking was responsible. Good experience at this property"
Carl
The price is ₩221,682
₩244,282 total
includes taxes & fees
Sep 27 - Sep 28
17. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.6 out of 10, Excellent, (3,676 reviews)
"Lovely resort with great food and great location . Good for a relaxing getaway ."
Pooja
The price is ₩227,498
₩329,586 total
includes taxes & fees
Sep 7 - Sep 8
18. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,427 reviews)
"Great stay"
Bernadette
The price is ₩177,852
₩200,534 total
includes taxes & fees
Sep 28 - Sep 29
19. Howard Johnson by Wyndham National City/San Diego South
Howard Johnson by Wyndham National City/San Diego South18.3 km from Otay Mesa
7.6 out of 10, Good, (1,123 reviews)
"Great hotel"
Erika
The price is ₩102,980
₩113,480 total
includes taxes & fees
Oct 4 - Oct 5
20. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,711 reviews)
"Loved the staff and location."
David
The price is ₩245,119
₩281,752 total
includes taxes & fees
Oct 5 - Oct 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
