Find hotels in Otay Mesa, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,842 reviews)
"Happy with are stay"
Yaril
The price is ₩189,282
₩215,309 total
includes taxes & fees
Sep 24 - Sep 25
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,020 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩148,455
₩168,867 total
includes taxes & fees
Sep 20 - Sep 21
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,090 reviews)
"Love it! Amazing stay! Will book again for our next trip."
Evelyn
The price is ₩241,583
₩266,212 total
includes taxes & fees
Sep 20 - Sep 21
4. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,069 reviews)
"Great stay!"
Samuel
The price is ₩197,724
₩217,882 total
includes taxes & fees
Sep 7 - Sep 8
5. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,649 reviews)
"Great hotel to stay."
Katsuya
The price is ₩154,064
₩169,779 total
includes taxes & fees
Sep 7 - Sep 8
6. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,385 reviews)
"Great stay"
Luis
The price is ₩156,842
₩178,407 total
includes taxes & fees
Sep 20 - Sep 21
7. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,470 reviews)
"Good breakfast, friendly staff and great housekeeping."
Jose
The price is ₩185,823
₩204,405 total
includes taxes & fees
Sep 8 - Sep 9
8. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,739 reviews)
"Great amenities, clean rooms, staff is extremely helpful."
Sharon
The price is ₩144,448
₩158,892 total
includes taxes & fees
Sep 7 - Sep 8
9. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,205 reviews)
"Just a great place to stay!"
Tracy
The price is ₩155,320
₩192,121 total
includes taxes & fees
Sep 20 - Sep 21
10. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,717 reviews)
"Very happy with the overall stay. Very efficient procedure from check in to check out."
Ivan
The price is ₩225,453
₩259,146 total
includes taxes & fees
Sep 7 - Sep 8
11. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,493 reviews)
"Great hotel,"
Keane
The price is ₩136,725
₩150,664 total
includes taxes & fees
Sep 20 - Sep 21
12. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.6 out of 10, Excellent, (3,669 reviews)
"Staff was very helpful ; very clean and , especially for being so close together airport, very quiet"
Celia
The price is ₩198,760
₩298,450 total
includes taxes & fees
Sep 2 - Sep 3
13. WoodSpring Suites Santee - San Diego Northeast
WoodSpring Suites Santee - San Diego Northeast30.9 km from Otay Mesa
8.6 out of 10, Excellent, (231 reviews)
"Great place to stay"
Adan
The price is ₩143,688
₩158,057 total
includes taxes & fees
Aug 27 - Aug 28
14. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (747 reviews)
"Fairly new, big, clean rooms and good breakfast"
Thomas
The price is ₩284,407
₩313,402 total
includes taxes & fees
Sep 6 - Sep 7
15. Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.4 out of 10, Good, (2,311 reviews)
"Great place to stay and very convenient"
Idanesha
The price is ₩98,065
₩107,872 total
includes taxes & fees
Sep 24 - Sep 25
16. Motel 6 El Cajon, CA - San Diego
Motel 6 El Cajon, CA - San Diego27 km from Otay Mesa
7.4 out of 10, Good, (1,785 reviews)
"Disgusting hotel with crackheads and homeless people"
Juan
The price is ₩92,510
₩106,014 total
includes taxes & fees
Aug 31 - Sep 1
17. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,120 reviews)
"The golf courses and hotel were great!"
Tom
The price is ₩171,459
₩205,184 total
includes taxes & fees
Sep 1 - Sep 2
18. Kings Inn San Diego
Kings Inn San Diego29.1 km from Otay Mesa
8.8 out of 10, Excellent, (3,715 reviews)
"Great place to stay"
Manuel
The price is ₩141,567
₩162,448 total
includes taxes & fees
Aug 27 - Aug 28
19. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,424 reviews)
"Great stay"
Bernadette
The price is ₩180,329
₩203,319 total
includes taxes & fees
Sep 17 - Sep 18
20. Four Points by Sheraton San Diego
Four Points by Sheraton San Diego32.4 km from Otay Mesa
8.2 out of 10, Very Good, (1,021 reviews)
"Really nice property, well maintained, clean rooms, and attentive staff"
Brian
The price is ₩198,953
₩228,686 total
includes taxes & fees
Aug 31 - Sep 1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
