Find hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very Good, (1,826 reviews)
"Clean rooms, friendly staff stay here every year"
JESUS
The price is ₩197,762
₩224,954 total
includes taxes & fees
Aug 9 - Aug 10
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,010 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ₩152,964
₩173,996 total
includes taxes & fees
Sep 7 - Sep 8
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,094 reviews)
"A lot of great places nearby and the hotel was great. The staff was very nice and helpful. The room was spacious with a nice layout."
Joanna
The price is ₩177,986
₩196,126 total
includes taxes & fees
Sep 7 - Sep 8
4. Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
8.0 out of 10, Very Good, (1,918 reviews)
"Friendly staff peaceful stay great breakfast clean hotel overall"
Gustavo
The price is ₩154,372
₩170,110 total
includes taxes & fees
Sep 7 - Sep 8
5. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (4,004 reviews)
"Very convenient location. Rooms and pool are great."
Stephanie
The price is ₩214,150
₩235,982 total
includes taxes & fees
Sep 7 - Sep 8
6. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very Good, (1,640 reviews)
"clean room, helpful staff, good breakfast, easy parking"
Xiaolei
The price is ₩155,991
₩171,902 total
includes taxes & fees
Sep 7 - Sep 8
7. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,403 reviews)
"Rooms are clean, friendly staff and wonderful breakfast"
yu
The price is ₩193,862
₩213,248 total
includes taxes & fees
Sep 7 - Sep 8
8. Studio 6 Suites San Ysidro, CA -San Diego South Bay
Studio 6 Suites San Ysidro, CA -San Diego South Bay6.9 km from Otay Mesa
8.0 out of 10, Very Good, (1,743 reviews)
"Hotel was great! Parking, room, & pool were nice. We stayed over for my birthday and the front desk employee played “las mañanitas” for me which made my day after having a rough trip! "
Betzy
The price is ₩119,668
₩136,351 total
includes taxes & fees
Aug 9 - Aug 10
9. Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.2 out of 10, Very Good, (1,085 reviews)
"Good stay for the price. The Staff was very friendly and accommodating."
elizabeth E
The price is ₩126,707
₩144,376 total
includes taxes & fees
Aug 9 - Aug 10
10. SureStay Hotel by Best Western Chula Vista San Diego Bay
SureStay Hotel by Best Western Chula Vista San Diego Bay14.7 km from Otay Mesa
8.0 out of 10, Very Good, (1,809 reviews)
"Very good location and good breakfast included."
UBALDO
The price is ₩112,784
₩124,282 total
includes taxes & fees
Aug 18 - Aug 19
11. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,204 reviews)
"Just a great place to stay!"
Tracy
The price is ₩157,417
₩194,713 total
includes taxes & fees
Sep 7 - Sep 8
12. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,711 reviews)
"Comfortable and close to food and highway."
Andrea
The price is ₩162,749
₩179,024 total
includes taxes & fees
Sep 8 - Sep 9
13. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,713 reviews)
"Very nice hotel, close to the SD Airport."
Brenda
The price is ₩234,521
₩269,571 total
includes taxes & fees
Aug 31 - Sep 1
14. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,353 reviews)
"Great stay"
Luis
The price is ₩172,209
₩195,888 total
includes taxes & fees
Sep 7 - Sep 8
15. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,491 reviews)
"Great hotel,"
Keane
The price is ₩139,322
₩153,526 total
includes taxes & fees
Sep 8 - Sep 9
16. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego24.6 km from Otay Mesa
8.4 out of 10, Very Good, (1,009 reviews)
"I will definitely stay here again....nice and quiet and very close to popular locations"
Jose
The price is ₩208,237
₩229,061 total
includes taxes & fees
Sep 8 - Sep 9
17. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (731 reviews)
"Fairly new, big, clean rooms and good breakfast"
Thomas
The price is ₩277,264
₩305,532 total
includes taxes & fees
Sep 7 - Sep 8
18. Sheraton San Diego Resort
Sheraton San Diego Resort28.1 km from Otay Mesa
8.4 out of 10, Very Good, (3,648 reviews)
"Perfect hotel for family fun."
Andre
The price is ₩175,983
₩273,493 total
includes taxes & fees
Aug 23 - Aug 24
19. Sycuan Casino Resort
Sycuan Casino Resort28.5 km from Otay Mesa
9.4 out of 10, Exceptional, (2,070 reviews)
"Lazy river and the food, great room great service"
Dale
The price is ₩174,715
₩209,081 total
includes taxes & fees
Aug 11 - Aug 12
20. Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG28.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,089 reviews)
"Very good hotel at the price with good choice of breakfast."
Tirthankar
The price is ₩193,494
₩222,412 total
includes taxes & fees
Sep 1 - Sep 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Pacific Beach
Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.
Mission Beach
Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
