What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on our traveler data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/ .

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Top Otay Mesa Hotels

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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

Yaril

₩231,889 total

includes taxes & fees

Aug 23 - Aug 24

2. Quality Suites San Diego Otay Mesa

Otay Mesa

Mia

₩174,963 total

includes taxes & fees

Sep 7 - Sep 8

3. Ayres Hotel San Diego South - Chula Vista

6.5 km from Otay Mesa

Evelyn

₩195,224 total

includes taxes & fees

Sep 7 - Sep 8

Premium bedding, in-room safe, desk, laptop workspace

4. Best Western Plus Marina Gateway Hotel

16.9 km from Otay Mesa

Samuel

₩237,293 total

includes taxes & fees

Sep 7 - Sep 8

5. Best Western Chula Vista/Otay Valley Hotel

7.1 km from Otay Mesa

Gustavo

₩171,054 total

includes taxes & fees

Sep 7 - Sep 8

6. Comfort Inn Chula Vista San Diego South

13 km from Otay Mesa

Katsuya

₩169,799 total

includes taxes & fees

Sep 7 - Sep 8

7. Holiday Inn Express San Diego South - Chula Vista by IHG

14.5 km from Otay Mesa

Jose

₩213,109 total

includes taxes & fees

Sep 7 - Sep 8

8. Studio 6 Suites San Ysidro, CA -San Diego South Bay

6.9 km from Otay Mesa

Arnold

₩121,014 total

includes taxes & fees

Aug 19 - Aug 20

9. La Quinta Inn by Wyndham San Diego Chula Vista

12.9 km from Otay Mesa

Luis

₩170,815 total

includes taxes & fees

Aug 30 - Aug 31

Premium bedding, desk, blackout drapes, soundproofing

10. Valli Hi Motel

7.9 km from Otay Mesa

elizabeth E

₩145,192 total

includes taxes & fees

Aug 19 - Aug 20

11. SureStay Hotel by Best Western Chula Vista San Diego Bay

14.7 km from Otay Mesa

Victor

₩124,972 total

includes taxes & fees

Aug 25 - Aug 26

12. Hampton Inn & Suites San Diego Airport Liberty Station

29.2 km from Otay Mesa

Ivan

₩262,345 total

includes taxes & fees

Aug 30 - Aug 31

13. Hercor Hotel - Urban Boutique

13.6 km from Otay Mesa

Keane

₩133,607 total

includes taxes & fees

Sep 8 - Sep 9

14. The Rambler Hotel

14.8 km from Otay Mesa

Tracy

₩196,011 total

includes taxes & fees

Sep 17 - Sep 18

15. Best Western Americana Inn

8 km from Otay Mesa

Luis

₩182,872 total

includes taxes & fees

Sep 13 - Sep 14

16. Best Western Plus La Mesa San Diego

24.6 km from Otay Mesa

Nelson Francisco

₩210,539 total

includes taxes & fees

Sep 13 - Sep 14

Studio Suite, 1 King Bed with Sofa bed, Balcony | View from room

17. Sheraton San Diego Resort

28.1 km from Otay Mesa

Andre

₩306,042 total

includes taxes & fees

Aug 23 - Aug 24

18. SpringHill Suites by Marriott Chula Vista Eastlake

10.5 km from Otay Mesa

Thomas

₩307,227 total

includes taxes & fees

Sep 7 - Sep 8

Outdoor pool, open 9:00 AM to 5:00 PM, cabanas (surcharge)

19. Sycuan Casino Resort

28.5 km from Otay Mesa

Andre

₩210,319 total

includes taxes & fees

Aug 24 - Aug 25

20. Holiday Inn Express San Diego Airport - Old Town by IHG

Mission Hills, 28.8 km from Otay Mesa

Tirthankar

₩229,527 total

includes taxes & fees

Sep 1 - Sep 2

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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

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A beach with surfers and swimmers during sunset.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

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A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

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Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

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An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

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Top Otay Mesa Hotel Reviews

The Dana on Mission Bay

8/10 Good

"At check in, staff was polite and professional. Via Expedia booking we were granted a room upgrade and two complimentary cocktails. The suite was clean and spacious, however a little dated and the Arcadia door failed to lock, but maintenance repaired it quickly. Next we went to firefly for appetizers and cocktails. The hostess was helpful and accommodating but our server was a no show until we made a comment to the bus person after two tables after us were attended. Afterwards, MANNY came to the rescue to take our orders, followed by a manager who apologized and offered a discount on our bill. The drinks were spot on and the calamari was excellent as were the Thai chicken wings. The musician playing had a good vibe and the volume was perfect ! Manny, thank you for being attentive and Johnny on the spot for my wife and daughter!"

Loews Coronado Bay Resort

8/10 Good

"The Loews was a good place to stay. We went there for our honeymoon, and I admit, in hindsight, I do not think I would have stayed there. It is definitely family friendly, and it cost too much for what we got out of it. Now, the staff was very friendly and helpful, the rooms were nice and serviced regularly, and the place was wonderful. However, the hot tubs did go out, the bugs were frequently bad, the beach access is not good at all, and everything was more expensive than advertised. Parking is around $50 per night, which wasn't covered up front. Resort fees are almost $50 per day as well which, again were not mentioned up front. And in general, the drinks, in room dining, and food was more than it was worth. Now, I would still recommend this place because the people were pretty nice but I would caution people to know what you are spending."

Find hotels in Otay Mesa, San Diego

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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2. Quality Suites San Diego Otay Mesa

3. Ayres Hotel San Diego South - Chula Vista

4. Best Western Plus Marina Gateway Hotel

5. Best Western Chula Vista/Otay Valley Hotel

6. Comfort Inn Chula Vista San Diego South

7. Holiday Inn Express San Diego South - Chula Vista by IHG

8. Studio 6 Suites San Ysidro, CA -San Diego South Bay

9. La Quinta Inn by Wyndham San Diego Chula Vista

10. Valli Hi Motel

11. SureStay Hotel by Best Western Chula Vista San Diego Bay

12. Hampton Inn & Suites San Diego Airport Liberty Station

13. Hercor Hotel - Urban Boutique

14. The Rambler Hotel

15. Best Western Americana Inn

16. Best Western Plus La Mesa San Diego

17. Sheraton San Diego Resort

18. SpringHill Suites by Marriott Chula Vista Eastlake

19. Sycuan Casino Resort

20. Holiday Inn Express San Diego Airport - Old Town by IHG

Where to stay in Otay Mesa

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Otay Mesa Hotel Reviews

The Dana on Mission Bay

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