Downtown South San Francisco, CA

San Francisco

An aerial view of a city with a large stadium, several schools, and a dense residential area.
An aerial view of a coastal city with a dense urban area, a large port, and a mountainous backdrop.
A panoramic view of San Francisco's South Peninsula, highlighting the city's dense urban areas, rolling hills, and the iconic Golden Gate Bridge in the distance.

Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is ₩165,964 per night from Oct 25 to Oct 26
₩165,964
₩194,093 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is ₩157,871 per night from Nov 22 to Nov 23
₩157,871
₩185,810 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
9/10 Wonderful! (6,430 reviews)
"This hotel is well located at the beginning of a Tram line. there is a good choice of restaurants walking distance. The breakfast selection is good for the hotel. the room was clean and spacious as we had twin beds. overall i had a great stay"

Reviewed on Oct 22, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is ₩148,099 per night from Nov 8 to Nov 9
₩148,099
₩228,963 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,716 reviews)
"Fantastic location"

Reviewed on Oct 22, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is ₩128,367 per night from Nov 8 to Nov 9
₩128,367
₩151,081 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
The price is ₩200,165 per night from Nov 22 to Nov 23
₩200,165
₩235,584 total
Nov 22 - Nov 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.6/10 Excellent! (1,825 reviews)
"Great service and clean and friendly"

Reviewed on Oct 22, 2026

Hilton San Francisco Union Square
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is ₩264,003 per night from Oct 23 to Oct 24
₩264,003
₩371,692 total
Oct 23 - Oct 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,544 reviews)
"Great location. Big hotel."

Reviewed on Oct 22, 2026

Hyatt Regency San Francisco
See all 4,187 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
A cityscape with tall buildings, a central plaza with palm trees, and a flag on one of the buildings.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops, and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Pier 39 and San Francisco Bay are top sights in Fisherman's Wharf, and you should be sure to explore the popular shops. Hop aboard the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop to see more sights in the area.

A city street with tall buildings, flags, and cars.

South of Market

Oracle Park and Chase Center are top sights in South of Market, and you should be sure to explore the popular shops. Hop aboard the metro at Yerba Buena-Moscone Station or Fourth-Brannan Station to see more sights in the area.

A vibrant mural on a building, depicting a large figure with a heart-shaped halo, surrounded by various characters in colorful attire.

Mission District

Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like SOMA Pilipinas.

Downtown South San Francisco, CA