San Francisco Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Hideki Yamagata
    Plan, book, travel with confidence
    payments icon
    Better together
    Save up to ₩9,995 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
Default Image

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or National Theater while you're exploring the area.

Find hotels in Casco Viejo

San Francisco Hotel Deals

Decapolis Hotel Panama City
Decapolis Hotel Panama City
4 out of 5
Avenida Balboa Con Multicentro, Panama City, Panama
Fully refundable
The price is ₩120,714 per night from Jun 14 to Jun 15
₩120,714
per night
Jun 14 - Jun 15
8.4/10 Very Good! (1,006 reviews)
"We arrived, checked in and went to sleep, in the morning the floor of our room was covered in water from a leaking toilet. The front desk was very efficient, and put us in an upgraded room for the remainder of our stay. The breakfast lived up to it's reputation, it had a great selection any a large ..."

Reviewed on May 31, 2024

Decapolis Hotel Panama City
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 out of 5
Avenida Balboa, Panama City
Fully refundable
The price is ₩182,901 per night from Jun 14 to Jun 15
₩182,901
per night
Jun 14 - Jun 15
8.2/10 Very Good! (419 reviews)
"Nice and clean ."

Reviewed on May 29, 2024

Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 out of 5
Italy Avenue, Punta Paitilla, Winston Churchill Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ₩161,386 per night from Jun 10 to Jun 11
₩161,386
per night
Jun 10 - Jun 11
9/10 Wonderful! (1,398 reviews)
"The pool is great for swimmers snd non swimmers. Very good buffet breakfast with daily variety."

Reviewed on May 28, 2024

Plaza Paitilla Inn Hotel
See all 1,278 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Francisco vacation package cost?
Much less than you might think — from a low , in fact! By bundling hotels, flights and car rentals into a custom-built vacation package, your San Francisco escape is only clicks away.
How do I get a cheap travel package to San Francisco?
Lock in flights that suit your schedule, add a hotel to your booking and watch how much you save with a San Francisco vacation package. It’s that easy! From flights and hotels to rental cars and activities, Expedia makes traveling on the cheap easy. And with more than 550 partner airlines and 1,000,000 hotel options around the globe to pick from, you’ll never be short of choice.
Where should I stay in San Francisco?
Make sightseeing easy by staying near San Francisco’s main attractions. Miraflores Locks and Metropolitan Cathedral of Panama are two which top many visitors’ bucket lists.
What are the top hotels in San Francisco?
If this will be your first visit to San Francisco, secure a room at Sublime Apartment City Center. Ph Boutique Quartier Atlapa or New Cozy Apartment Ocean View. Quartier Del Mar. Both hotels will make you feel at home and are popular options with lots of travelers.
How far in advance should I book my San Francisco vacation?
It can be hard to know when is the ideal time to book your trip to San Francisco. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to your departure date. If you’re eager to escape on a last-minute getaway, no need to fret! There are unbeatable deals announced on Expedia every day.
What does an Expedia San Francisco travel package include?
That mostly depends on you. You can choose from a range of San Francisco packages, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a flight and a rental car. Once you’ve made your booking, you can add the fun stuff like experiences and tours. Whatever your ideal San Francisco vacation looks like, you’re sure to save!
What should I know before booking a San Francisco travel package?
So many places to go, so many things to see and do. With a travel package, you’ll be able to afford more of them. Bundle your hotels, flights and rental cars and land big savings.
Can I choose my airline with a San Francisco Expedia vacation package?
Yes, definitely. Expedia has more than 550 airline partners to choose from worldwide. With such a huge range of choice, finding the ideal carrier to whisk you off to San Francisco won’t be difficult.
If I'm not able to travel, can I cancel my San Francisco vacation package?
Your situation can change in a flash, so yes, you can. You may be able to amend or cancel your San Francisco vacation package for free if you’ve booked in the last 24 hours. For older bookings, you can still make changes, but your car rental company, airline or hotel may charge a fee. Need more information? Look up our Customer Service Portal. We’ll help make sure your trip goes off without a hitch.

Discover the most popular places to visit in San Francisco

Image for Multiplaza Pacific Mall

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Image for Avenida Balboa

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
Image for Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera

Other vacations you might like

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.