Lodging Image

Southeast Missouri 3 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri 3 Star Hotels

Tonight
Oct 14 - Oct 15
Tomorrow
Oct 15 - Oct 16
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for Southeast Missouri 3-star hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Darnetta
₩133,467
₩150,570 total
includes taxes & fees
Oct 18 - Oct 19
Drury Plaza Hotel Cape Girardeau Conference Center
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Tim
₩125,458
₩144,245 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Sikeston, MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
An outdoor patio with tables and chairs, a stone wall, and large windows.
A hotel room with two beds, a nightstand, a lamp, and a chair.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
₩107,366
₩116,197 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A hotel lobby with a reception desk, seating area, and a television screen.

4. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
₩112,123
₩126,670 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Poplar Bluff by IHG
A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.
A gym with treadmills, elliptical machines, and a mirrored wall.
An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.
Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.

5. Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
Hayti
United States
Cynthia
₩131,674
₩150,075 total
includes taxes & fees
Nov 1 - Nov 2
Drury Inn & Suites Hayti Caruthersville
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
₩135,015
₩152,315 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a reception desk, seating area, and large windows.
A hotel room with a bed, a desk, a chair, a sofa, and a TV.
An indoor swimming pool with a clear view of the outside through large windows.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

7. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
₩125,458
₩141,735 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Poplar Bluff
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A restaurant with a brick wall, a flat-screen TV, and a bar area.

8. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Debra S
₩106,771
₩112,883 total
includes taxes & fees
Oct 18 - Oct 19
Drury Inn & Suites Jackson MO
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A spacious living room with a sofa set, a coffee table, and a dining area.
A lobby with seating areas, a reception desk, and a bar.

9. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
₩166,983
₩189,216 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Cape Girardeau Downtown
A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.
A modern hotel room with a kitchen area, a dining space, and a living area with a view.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.
A parking lot with several cars, a building with a green roof, and a view of a lake.

10. Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville
Caruthersville
United States
Jessica
₩162,178
₩184,442 total
includes taxes & fees
Oct 15 - Oct 16
Century Casino & Hotel Caruthersville
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A reception area with a wooden counter, a coffee machine, and a display of pastries.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.
A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

11. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Nancy
₩130,209
₩147,103 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A swimming pool with lounge chairs and a view of the night sky.
A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.

12. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus
United States
Debra S
₩112,323
₩128,442 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

13. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
₩120,119
₩135,511 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Cape Girardeau
A hotel room with a large bed, a desk with a lamp, a television, and a bathroom visible in the background.
A restaurant with multiple tables and chairs, a counter with a coffee machine, and framed pictures on the walls.
A multi-story hotel with a brick facade and large windows, featuring a parking lot in front.
An indoor swimming pool with a tiled edge, surrounded by lounge chairs and a potted plant.

14. Baymont by Wyndham Festus

Baymont by Wyndham Festus
Festus
United States
Gretchen
₩81,689
₩93,412 total
includes taxes & fees
Nov 1 - Nov 2
Baymont by Wyndham Festus
A red wooden mill with a small bridge over a flowing river, surrounded by lush greenery.
A playground with a slide, climbing structures, and a small shelter.
A dining area with a round table and chairs, large windows with curtains, and a whiteboard on the wall.
A row of yellow buildings with white railings and a covered front porch.

15. Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
Mountain View
United States
Joanne
₩132,145
₩143,261 total
includes taxes & fees
Oct 15 - Oct 16
Honeysuckle Inn - Mountain View
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

16. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
₩134,815
₩153,317 total
includes taxes & fees
Oct 25 - Oct 26
Fairfield Inn & Suites by Marriott Sikeston
A bedroom with a bed, a desk, and a chair. There is a window with curtains, a radiator, and a wall-mounted shelf with a towel.
A motel with a parking lot, a covered picnic area, and a row of rooms with individual entrances.
A group of people sitting at picnic tables outdoors, surrounded by trees and a fenced area.
A playground with slides and swings, a mailbox, and a caution sign.

17. Current River Inn

Current River Inn
Van Buren
United States
Doreen
₩145,360
₩157,306 total
includes taxes & fees
Oct 19 - Oct 20
Current River Inn
Property amenity
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

18. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Rubin
₩145,493
₩165,461 total
includes taxes & fees
Oct 22 - Oct 23
TownePlace Suites by Marriott Sikeston
A living room with a blue wall, a fireplace, a sofa, and a chair.
A bar area with stools and a counter where a bartender is serving drinks.
A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.
A brick building with a sign reading "Mercantile & Hotel".

19. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
Miranda
₩141,279
₩153,782 total
includes taxes & fees
Oct 15 - Oct 16
EC Reed's Mercantile and Hotel
A bedroom with a bed, bedside table, and wall-mounted light fixtures.
A cozy living room with a sofa, armchairs, a coffee table, and a lamp. There are wall art pieces and a mirror.
A cabin with a porch and steps leading to a deck, situated near a body of water.
A wooden cabin with a balcony, a small attached room, and a clear sky in the background.

20. Johnson's Shut-ins State Park

Johnson's Shut-ins State Park
Middle Brook
United States
Aleksandr
Johnson's Shut-ins State Park
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
₩152,568
₩172,118 total
Oct 18 - Oct 19
includes taxes & fees
9.4/10 Exceptional! (679 reviews)
The Riverview
Urban Lofts

Urban Lofts

104 North Jackson Street Perryville MO
Get ratesUrban Lofts
Still don't see what you're looking for?
See all properties in Southeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"They serve an amazing happy hour and breakfast with à large selection of food. Very nice and comfortable room"
Christine 1-night trip
Posted 8 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Seamless check-in and check-out. Reserved the room through Expedia only moments before stopping for the night. Everything in the room seemed cleaned and sanitized. The breakfast on Sunday morning was quite delicious before we got back on the road to home."
Robyn 1-night trip
Posted 11 hours ago
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"The food was excellent"
DENNIS 2-night trip
Posted 1 day ago
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Everything perfect. Drury Inns sweat the details."
Richard 1-night trip
Posted 1 day ago
Drury Inn & Suites Sikeston, MO

Frequently asked questions

What are the best 3-star hotels in Southeast Missouri?
If you're staying in Cape Girardeau for your Southeast Missouri vacation, you'll find some cozy 3-star hotels. Many Expedia travelers book Courtyard by Marriott Cape Girardeau Downtown. Around 0.64 kilometers west of the downtown area, it features a terrace and a cafe. Another highly rated escape is Drury Plaza Hotel Cape Girardeau Conference Center. Book a room here and enjoy access to a swimming pool and high-speed internet services, and be approximately 8 kilometers west of the center.
How much does it cost to stay in a 3-star hotel in Southeast Missouri?
Use Expedia's sort and search filters to land an affordable 3-star hotel for your Southeast Missouri break. Just set your maximum rate with our pricing tool. You can also pick your amenities, preferred neighborhood and lots more.
  • Search for the lowest price per night right now from ₩172,118
What is the difference between a 4-star and 3-star hotel in Southeast Missouri?
Relaxation is effortless in 3-star hotels in Southeast Missouri. In addition to pleasant surroundings, these more affordable stays come with a wealth of amenities like WiFi, coffee maker and on-site gym. A 4-star hotel offers a more sophisticated experience with upscale features such as an on-site spa center, outdoor or indoor pool and more spacious rooms. Regardless of your desired hotel category or budget, we have the ideal match for you.

Explore a world of travel with Expedia