The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

₩121,963

₩143,597 total

includes taxes & fees

Oct 14 - Oct 15

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Margaret

₩126,721

₩149,205 total

includes taxes & fees

Sep 29 - Sep 30

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A modern lobby with blue seating, a reception desk, and large windows.

3. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Maxine

₩151,113

₩185,829 total

includes taxes & fees

Oct 2 - Oct 3

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

4. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

mike

₩157,968

₩185,357 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

A snack vending machine with various snack options.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

₩176,939

₩211,155 total

includes taxes & fees

Oct 8 - Oct 9

A breakfast buffet with labeled sections for fruit and cereal.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A Holiday Inn Express & Suites building with a covered entrance, a truck with the hotel branding, and a clear sky.

A conference room with a long table, chairs, water bottles, a phone, and a notepad.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

₩167,598

₩205,502 total

includes taxes & fees

Sep 27 - Sep 28

A buffet with fruits, pastries, and beverages.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

7. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Anthony

₩162,309

₩189,883 total

includes taxes & fees

Oct 11 - Oct 12

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

₩195,897

₩233,780 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

₩156,580

₩183,728 total

includes taxes & fees

Oct 2 - Oct 3

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A modern hotel lobby with a sectional sofa, round tables, and a bar area.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

₩188,314

₩224,730 total

includes taxes & fees

Sep 25 - Sep 26

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

₩92,247

₩108,942 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A parking lot with several cars, a U-Haul truck, and a building with a green sign for HomeTowne Studios.

A compact kitchen with a sink, stove, and white cabinets.

A reception area with a green wall, a reception desk, and a wooden floor.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

₩94,871

₩115,969 total

includes taxes & fees

Sep 29 - Sep 30

A modern living room with a flat-screen TV, a sofa, a coffee table, and a potted plant.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A brick building with a central entrance, numbered 155, and a sign indicating 'Lobby'.

A modern kitchen with dark cabinets, a white countertop, a stove, a microwave, and a sink.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

₩103,031

₩125,943 total

includes taxes & fees

Sep 24 - Sep 25

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

₩86,299

₩105,864 total

includes taxes & fees

Oct 3 - Oct 4

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A gym with treadmills, stationary bikes, and a weight machine.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

₩186,816

₩216,570 total

includes taxes & fees

Sep 27 - Sep 28

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Jeana

₩186,816

₩221,795 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A snack and treat display with various products, including chips and beverages, in a store setting.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

17. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jennifer

₩187,817

₩221,491 total

includes taxes & fees

Oct 5 - Oct 6

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A hotel room with two beds, a desk, and a chair.

A spacious lobby with a bar area, seating arrangements, and a clock on the wall.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

18. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Kenney

₩218,461

₩251,205 total

includes taxes & fees

Oct 5 - Oct 6

An outdoor patio with a fire pit, seating, and a building in the background.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

19. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

₩162,309

₩197,969 total

includes taxes & fees

Oct 11 - Oct 12

A brick building with a sign reading "Country Inn & Suites."

A modern kitchen with blue cabinetry, a central island with stools, pendant lighting, and a variety of kitchen appliances and utensils.

An indoor swimming pool with a tiled floor, a central window, and multiple chairs around the pool.

A spacious living room with a large window, a wooden bookshelf, a green sofa, and a coffee table.

20. Country Inn & Suites by Radisson, St. Charles Historic District

12.5 km from James S. McDonnell Prologue Room

Eland

₩187,943

₩215,998 total

includes taxes & fees

Oct 18 - Oct 19

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,247 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,729 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,003 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,419 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 224 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Wingate by Wyndham St. Louis Airport

8/10 Good

"Adrienne was so friendly and helpful with checking in. Also shuttle service was terrific!"

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Very clean rooms, staff was very nice! One of the best rooms I've stayed in a long time."

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Great place to stay, close to the airport, can use the shuttle and pay for parking at the hotel, cheaper than at the airport."

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

10/10 Excellent

"Cool"

Pear Tree Inn St. Louis Airport

10/10 Excellent

"We got in early in the morning. We called from airport, the shuttle was prompt . Bed was comfortable. Staff was nice. My partner ate breakfast, he said was good.."

Hyatt Select St. Louis Airport

10/10 Excellent

"Great"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"This was a great place with a welcoming atmosphere. The staff were outstanding—friendly, attentive, and professional—making the experience even more enjoyable. The people there were remarkable, contributing to a lively and positive environment."

Hilton St. Louis Airport

10/10 Excellent

"Service"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

See properties

Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

See properties

Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

See properties

St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

See properties

St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

See properties

St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

See properties

New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

See properties

Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

Find hotels near James S. McDonnell Prologue Room, St. Louis from ₩105,864

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Hyatt Select St. Louis Airport

4. Drury Inn & Suites St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Hampton Inn & Suites St. Louis at Forest Park

18. The Knight Center at Washington University

19. Courtyard by Marriott St. Louis Brentwood

20. Country Inn & Suites by Radisson, St. Charles Historic District

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Wingate by Wyndham St. Louis Airport

Drury Inn & Suites St. Louis Airport

Hampton Inn By Hilton St Louis Airport

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Pear Tree Inn St. Louis Airport

Hyatt Select St. Louis Airport

Renaissance St. Louis Airport Hotel

Hilton St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions