The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Rebecca

₩145,884 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

2. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Cindy

₩162,630 total

includes taxes & fees

Nov 15 - Nov 16

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

3. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Thadora

₩185,612 total

includes taxes & fees

Nov 12 - Nov 13

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

4. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Ethan

₩185,784 total

includes taxes & fees

Nov 15 - Nov 16

A modern bar area with a central bar counter, seating, and decorative plants.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Janet

₩187,429 total

includes taxes & fees

Nov 19 - Nov 20

A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

₩199,331 total

includes taxes & fees

Nov 17 - Nov 18

A buffet with fruits, pastries, and beverages.

7. Renaissance St. Louis Airport Hotel

2 km from James S. McDonnell Prologue Room

Joy

₩177,611 total

includes taxes & fees

Nov 27 - Nov 28

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Loney

₩216,461 total

includes taxes & fees

Nov 20 - Nov 21

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Kimberly

₩155,184 total

includes taxes & fees

Nov 23 - Nov 24

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Julie

₩194,977 total

includes taxes & fees

Nov 20 - Nov 21

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Annalyn

₩99,458 total

includes taxes & fees

Nov 30 - Dec 1

A reception desk with a cityscape on the monitor, a blue-lit ceiling, and a sign for key drop-off.

12. Travelodge by Wyndham St. Louis

2.4 km from James S. McDonnell Prologue Room

Derly

₩103,380 total

includes taxes & fees

Dec 6 - Dec 7

A hotel room with a bed, a chair, a nightstand with a lamp, a picture on the wall, and a window with curtains.

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

₩96,115 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Donald

₩91,964 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Madhusudhana Rao

₩229,482 total

includes taxes & fees

Nov 15 - Nov 16

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Stacey Rochelle

₩207,541 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio with a fire pit, seating, and a building in the background.

17. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Anna

₩196,747 total

includes taxes & fees

Nov 15 - Nov 16

A large banquet hall with round tables set for dining, featuring chandeliers and large windows.

18. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

April

₩214,984 total

includes taxes & fees

Nov 24 - Nov 25

A brick building with a sign reading "Country Inn & Suites."

19. Country Inn & Suites by Radisson, St. Charles Historic District

12.5 km from James S. McDonnell Prologue Room

Stewart

₩200,921 total

includes taxes & fees

Nov 29 - Nov 30

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

20. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Edmond

₩209,922 total

includes taxes & fees

Nov 15 - Nov 16

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	2.5 star property	9.4 Exceptional 3,366 reviews	View
Wingate by Wyndham St. Louis Airport	3.0 star property	9.2 Wonderful 1,737 reviews	View
Hyatt Select St. Louis Airport	2.5 star property	9.2 Wonderful 1,019 reviews	View
Drury Inn & Suites St. Louis Airport	3.0 star property	9.2 Wonderful 1,463 reviews	View
Hampton Inn By Hilton St Louis Airport	2.5 star property	9.0 Wonderful 258 reviews	View

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

See properties

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

St. Ann

10/10 Excellent

Jane

A well-lit lobby with a chandelier, potted plants, and a seating area.

Truitt Hotel

Lafayette Square

10/10 Excellent

Boutique hotel that retains a welcoming feeling. Super well designed with thoughtful touches throughout. For example, the locally made, complimentary chocolates were the prettiest chocolates I’ve ever come across! Neighborhood is in one of St. Louis’ historic districts, and very walkable to a big park, coffee shop, and other restaurants. On a lovely fall day, there were lots of people walking around, biking, enjoying life—so it felt really cohesive with the vibes/intention of the hotel, i.e....

valerie

Drury Plaza Hotel St. Louis Brentwood

Brentwood

10/10 Excellent

Lisa

Drury Inn & Suites St. Louis Airport

Edmundson

10/10 Excellent

Veronica

Hyatt Select St. Louis Airport

Woodson Terrace

10/10 Excellent

Chandis

A rooftop terrace with a fire feature, outdoor seating, and a city view.

Residence Inn By Marriott St. Louis Clayton

Clayton

10/10 Excellent

Jamie

A rooftop terrace with wicker furniture, offering a city view.

Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis

10/10 Excellent

Richard

The Knight Center at Washington University

St. Louis

10/10 Excellent

amy

A hotel lobby with a hot tub, a pool, and outdoor seating.

Drury Plaza Hotel St. Louis Creve Coeur

Creve Coeur

10/10 Excellent

Rachel

Courtyard by Marriott St. Louis Brentwood

Richmond Heights

10/10 Excellent

Tom

Hampton Inn & Suites St. Louis at Forest Park

Dogtown

10/10 Excellent

Linda

Drury Inn & Suites St. Louis Forest Park

Clifton Heights

10/10 Excellent

This is a fantastic hotel, especially if you are traveling with kids. The rooms were clean and modern. The amenities were impressive: the free drinks for the adults, and the free breakfast and dinner for kids (and adults.) It’s close to Forest Park and felt very safe: lots of families and kids. Despite all of the kids, though, my room was super quiet. Andrew and Kevin at the front desk were super enthusiastic and helpful, and made check-in a breeze. For the price, this hotel is amazing and I...

Mitchell

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

Fairfield Inn & Suites St Louis Westport

Westport

10/10 Excellent

Heather

An indoor pool area with a hot tub, seating, and a stone wall.

Drury Plaza Hotel St. Louis Union Station

Downtown West

10/10 Excellent

In town for the NCAA Tournament with my son. Staff was friendly, and attentive. Breakfast was honesty the best hotel free breakfast I have had in 5 years if travel hockey. The parking garage is secured after dark to protect your cars and personal safety coming and going into the hotel. The area around the hotel is clean, well lit, and feels safe. It is downtown in a major city, so be smart. However there was no feeling of threats. Work out room was small, but clean with free weights,...

Anonymous traveler

The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

Live by Loews - St.Louis

Downtown St. Louis

10/10 Excellent

Jennifer

Frequently Asked Questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

Find hotels near James S. McDonnell Prologue Room, St. Louis from ₩122,862

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Wingate by Wyndham St. Louis Airport

3. Hyatt Select St. Louis Airport

4. Drury Inn & Suites St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. Travelodge by Wyndham St. Louis

13. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Courtyard by Marriott St. Louis Brentwood

18. The Knight Center at Washington University

19. Country Inn & Suites by Radisson, St. Charles Historic District

20. Hampton Inn & Suites St. Louis at Forest Park

Compare popular hotels close to James S. McDonnell Prologue Room

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Top James S. McDonnell Prologue Room Hotel Reviews

Pear Tree Inn St. Louis Airport

10/10 Excellent

Frequently Asked Questions

What's the area like around James S. McDonnell Prologue Room?

What's the best hotel to stay close to James S. McDonnell Prologue Room?

How many hotels will I find near James S. McDonnell Prologue Room?

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

What can I see and do near James S. McDonnell Prologue Room?