The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

1. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

₩122,859

₩144,652 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A corridor with snack bags, a refrigerator stocked with Mountain Dew, and a view into a room with a ceiling fan.

A modern lobby with blue seating, a reception desk, and large windows.

2. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Maxine

₩150,178

₩184,680 total

includes taxes & fees

Oct 2 - Oct 3

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A pool area with two hot tubs, seating, and a view of the outdoors.

3. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Hope

₩156,990

₩184,209 total

includes taxes & fees

Oct 4 - Oct 5

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

4. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Tessa

₩127,651

₩150,300 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A snack vending machine with various snack options.

A dining area with tables and chairs, a blue sofa, and a patterned carpet.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

₩175,844

₩209,849 total

includes taxes & fees

Oct 8 - Oct 9

A buffet with fruits, pastries, and beverages.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

6. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Anthony

₩161,304

₩188,707 total

includes taxes & fees

Oct 15 - Oct 16

A breakfast buffet with labeled sections for fruit and cereal.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A conference room with a long table, chairs, water bottles, a phone, and a notepad.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

7. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

₩169,291

₩207,489 total

includes taxes & fees

Oct 4 - Oct 5

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

₩194,685

₩232,332 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A hotel room with a bed, a desk, a chair, a small table, a framed artwork, and a bathroom with a mirror and sink.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

₩155,611

₩182,591 total

includes taxes & fees

Oct 2 - Oct 3

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

₩187,148

₩223,339 total

includes taxes & fees

Sep 26 - Sep 27

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

₩91,677

₩108,270 total

includes taxes & fees

Oct 14 - Oct 15

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

A reception area with a green wall, a reception desk, and a wooden floor.

A parking lot with several cars, a U-Haul truck, and a building with a green sign for HomeTowne Studios.

A compact kitchen with a sink, stove, and white cabinets.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

₩95,568

₩116,820 total

includes taxes & fees

Sep 28 - Sep 29

A modern living room with a flat-screen TV, a sofa, a coffee table, and a potted plant.

A hotel room with a bed, bedside tables, a desk, and a window with a city view.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A brick building with a central entrance, numbered 155, and a sign indicating 'Lobby'.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

₩102,394

₩125,165 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A spacious lobby with a patterned tile floor, a staircase, and seating areas.

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

₩80,973

₩99,587 total

includes taxes & fees

Oct 4 - Oct 5

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A spacious lobby with a large sectional sofa, a reception desk, and a bar area.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A gym with treadmills, stationary bikes, and a weight machine.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

₩185,660

₩215,230 total

includes taxes & fees

Oct 1 - Oct 2

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

A spa bath with a sign indicating a capacity of 8 persons.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Jeana

₩185,660

₩220,421 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

A Courtyard by Marriott hotel with a modern facade, multiple floors, and a well-lit entrance.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

17. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

₩155,502

₩189,909 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

A snack and treat display with various products, including chips and beverages, in a store setting.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

18. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jennifer

₩189,196

₩223,117 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

A hallway with a chandelier, a dining table with chairs, and a vase of flowers.

A hotel room with a four-poster bed, a dining table with chairs, a bedside table with lamps, and a floral-patterned rug.

A wooden table set for a meal under a tent with string lights, surrounded by chairs on a grassy area.

19. Grand Center Inn

15.5 km from James S. McDonnell Prologue Room

Leon and Janis

₩244,380

₩288,196 total

includes taxes & fees

Oct 1 - Oct 2

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

A modern hotel room with a large bed, a desk, a sofa, and a view of the city.

20. Residence Inn By Marriott St. Louis Clayton

Clayton, 11 km from James S. McDonnell Prologue Room

Donna

₩230,849

₩277,592 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,255 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,004 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,416 reviews	View
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,712 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 224 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Travelodge by Wyndham St. Louis

8/10 Good

"It was what I expected"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"We had a great experience at the hotel. The Internet you do have to pay extra for if you hook up your devices. Also parking is about $25 a night before taxes. All and all a good experience"

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

10/10 Excellent

"They accommodated me with a late check out. I appreciate that!"

Wingate by Wyndham St. Louis Airport

8/10 Good

"Adrienne was so friendly and helpful with checking in. Also shuttle service was terrific!"

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Great place to stay, close to the airport, can use the shuttle and pay for parking at the hotel, cheaper than at the airport."

Hilton St. Louis Airport

10/10 Excellent

"Service"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

Find hotels near James S. McDonnell Prologue Room, St. Louis from ₩99,587

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Pear Tree Inn St. Louis Airport

2. Hyatt Select St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Wingate by Wyndham St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Renaissance St. Louis Airport Hotel

7. Holiday Inn Express & Suites St Louis Airport by IHG

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Courtyard by Marriott St. Louis Brentwood

18. Hampton Inn & Suites St. Louis at Forest Park

19. Grand Center Inn

20. Residence Inn By Marriott St. Louis Clayton

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Travelodge by Wyndham St. Louis

Renaissance St. Louis Airport Hotel

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Wingate by Wyndham St. Louis Airport

Hampton Inn By Hilton St Louis Airport

Hilton St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions