The Best Hotels Closest to James S. McDonnell Prologue Room in St. Louis for 2026

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Our top choices for James S. McDonnell Prologue Room hotels

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with two beds, a desk, a chair, and a large window with curtains.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

1. Wingate by Wyndham St. Louis Airport

2.5 km from James S. McDonnell Prologue Room

Mary

₩126,606

₩149,070 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A seating area with three grey armchairs and a central glass-top table, a wooden floor, and a view of parked cars through large windows.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

2. Pear Tree Inn St. Louis Airport

2.6 km from James S. McDonnell Prologue Room

Monica

₩121,853

₩143,467 total

includes taxes & fees

Oct 4 - Oct 5

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A hotel room with a bed, two armchairs, a sofa, a small table, and a nightstand.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

3. Drury Inn & Suites St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Hope

₩155,705

₩182,700 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A modern lobby with blue seating, a reception desk, and large windows.

4. Hyatt Select St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

Maxine

₩148,948

₩183,168 total

includes taxes & fees

Oct 3 - Oct 4

An indoor swimming pool with clear glass walls, blue lounge chairs, and a lifeguard stand.

A snack vending machine with various snack options.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A hotel lobby with a reception desk, seating area, and a view of the parking lot.

5. Hampton Inn By Hilton St Louis Airport

2 km from James S. McDonnell Prologue Room

Leia

₩174,404

₩208,129 total

includes taxes & fees

Oct 8 - Oct 9

A breakfast buffet with labeled sections for fruit and cereal.

A hotel room with a large bed, a separate bathroom with a bathtub, a desk with a chair, and a large window with curtains.

A gym with treadmills, stationary bikes, and a mirrored wall.

A coffee station with two coffee machines and a variety of coffee pods and cups.

6. Holiday Inn Express & Suites St Louis Airport by IHG

2 km from James S. McDonnell Prologue Room

Keneace

₩167,905

₩205,790 total

includes taxes & fees

Oct 4 - Oct 5

A buffet with fruits, pastries, and beverages.

A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

7. Renaissance St. Louis Airport Hotel

Berkeley, 2 km from James S. McDonnell Prologue Room

Anthony

₩159,983

₩187,161 total

includes taxes & fees

Oct 15 - Oct 16

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.

A swimming pool with a glass enclosure, a lounge area with orange chairs, and a view of a landscaped garden.

8. Marriott St. Louis Airport

2.4 km from James S. McDonnell Prologue Room

Chris

₩201,418

₩240,368 total

includes taxes & fees

Oct 2 - Oct 3

A modern interior with a wooden panel wall, a kitchen area, and a dining space with pendant lighting.

A modern hotel with a prominent DoubleTree by Hilton sign, a well-lit entrance, and a landscaped front yard.

A hotel room with a large bed, a chair, a table, and a cityscape mural on the wall.

A modern kitchen with a marble countertop, red ceiling, and pendant lighting.

9. DoubleTree by Hilton St. Louis Airport

2.1 km from James S. McDonnell Prologue Room

Samone

₩154,337

₩181,095 total

includes taxes & fees

Oct 2 - Oct 3

A bar area with a long counter, multiple seating options, and a television screen displaying a program.

A hotel lobby with a central seating area featuring sofas and tables, a large TV screen displaying a sports game, and a bar area with chairs and a counter.

A spacious lobby with a reception desk, seating area, and a modern ceiling design.

A multi-story hotel with a central courtyard, surrounded by trees and a parking lot.

10. Hilton St. Louis Airport

1.9 km from James S. McDonnell Prologue Room

raymond

₩185,616

₩221,512 total

includes taxes & fees

Oct 2 - Oct 3

A hotel dining area with multiple tables and chairs, a sofa, and a large window with curtains.

A hotel room with two beds, a desk with a lamp, a television, and a painting on the wall.

A hotel room with a round wooden dining table, a sofa, two lamps, and framed pictures on the walls.

A hotel with a beige facade, a clear sign reading "Quality Inn," and a parking lot with a red car.

11. Quality Inn Florissant - St Louis

3.1 km from James S. McDonnell Prologue Room

Sharonda

₩90,926

₩107,384 total

includes taxes & fees

Oct 18 - Oct 19

A parking lot with multiple cars, a building with a green and beige facade, and a sign for Home Towne Studios.

A compact kitchenette with a sink, stove, microwave, and a white refrigerator.

A hotel room with a bed, a desk, a chair, a flat-screen TV, and a wooden floor.

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

2.9 km from James S. McDonnell Prologue Room

Kimberly

₩94,785

₩115,863 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, bedside tables, a heater, and a view of the city.

A modern living room with a grey sofa, a red bench, a dark wooden table, and a TV on a stand.

A stairwell with a metal railing, a trash can, and a window with a view of trees.

A multi-story brick building with a central entrance, parking lot, and designated handicapped parking spaces.

13. Welcome Suites Hazelwood

3 km from James S. McDonnell Prologue Room

Arutyun

₩101,555

₩124,140 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a bed, bedside table, lamp, TV, and a desk with a chair.

A kitchen with a built-in refrigerator, a coffee maker, and a microwave. There are cabinets and a countertop with various items on it.

A spacious dining area with multiple tables and chairs, a kitchen area with dark cabinets, and a flat-screen TV mounted on the wall.

A reception area with a marble floor, a reception desk, and a sign that says "Quality."

14. Quality Inn Saint Louis Airport

2 km from James S. McDonnell Prologue Room

Gordon

₩80,432

₩98,915 total

includes taxes & fees

Oct 4 - Oct 5

A modern lobby with orange seating, a flat-screen TV, and a stone accent wall.

A gym with treadmills, stationary bikes, and a weight machine.

A hotel room with two beds, a headboard, bedside lamps, a clock, and a window with curtains.

A hotel pool area with a hot tub, lounge chairs, and a 'No Diving Allowed' sign.

15. Drury Plaza Hotel St. Louis St. Charles

12.8 km from James S. McDonnell Prologue Room

Robert

₩184,140

₩213,468 total

includes taxes & fees

Oct 1 - Oct 2

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

A spa bath with a sign indicating a capacity of 8 persons.

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

A Drury Plaza Hotel with a large parking lot and multiple cars parked in front.

16. Drury Plaza Hotel St. Louis Brentwood

13.6 km from James S. McDonnell Prologue Room

Janell

₩184,140

₩218,616 total

includes taxes & fees

Oct 11 - Oct 12

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

17. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 14.4 km from James S. McDonnell Prologue Room

Jennifer

₩187,647

₩221,290 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor patio with a fire pit, seating, and a building in the background.

A modern bar area with a wooden counter, a beverage dispenser, and a menu board.

A modern hotel lobby with a bar area, a large dining table, and a seating area with chairs.

A modern bar area with a digital menu display, a seating area with a long table and chairs, and a wall with a colorful abstract design.

18. Courtyard by Marriott St. Louis Brentwood

13.5 km from James S. McDonnell Prologue Room

Aaron

₩154,229

₩188,355 total

includes taxes & fees

Oct 4 - Oct 5

A courtyard with outdoor seating, a central fountain, and a view of a tower.

A buffet setup with various food items, a coffee station, and a refrigerator with beverages.

A hotel room with two beds, a desk, and a chair.

The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

19. The Knight Center at Washington University

11.4 km from James S. McDonnell Prologue Room

Kenney

₩229,041

₩263,370 total

includes taxes & fees

Sep 28 - Sep 29

A rooftop terrace with a fire feature, outdoor seating, and a city view.

A modern hotel room with a large bed, a desk, a sofa, and a view of the city.

A modern bar area with round tables and blue chairs, a wooden bar counter, and a television mounted on the wall.

A modern lounge area with a fireplace, a flat-screen TV, and a dining area with chairs and tables.

20. Residence Inn By Marriott St. Louis Clayton

Clayton, 11 km from James S. McDonnell Prologue Room

Donna

₩230,192

₩276,784 total

includes taxes & fees

Oct 2 - Oct 3

View all properties

Compare popular hotels close to James S. McDonnell Prologue Room

Property	Property class	Guest rating
Wingate by Wyndham St. Louis Airport	9.2 Wonderful 1,717 reviews	View
Pear Tree Inn St. Louis Airport	9.2 Wonderful 3,265 reviews	View
Drury Inn & Suites St. Louis Airport	9.2 Wonderful 1,423 reviews	View
Hyatt Select St. Louis Airport	9.2 Wonderful 1,004 reviews	View
Hampton Inn By Hilton St Louis Airport	9.0 Wonderful 225 reviews	View

Top James S. McDonnell Prologue Room Hotel Reviews

Hampton Inn By Hilton St Louis Airport

10/10 Excellent

"Short stay no problems"

Renaissance St. Louis Airport Hotel

10/10 Excellent

"Staff was great! Would come back to stay."

Pear Tree Inn St. Louis Airport

10/10 Excellent

"Great value, free breakfast and free parking, and helpful and friendly staff."

Drury Inn & Suites St. Louis Airport

10/10 Excellent

"Wonderful stay! The staff in all departments are very helpful and friendly."

Wingate by Wyndham St. Louis Airport

10/10 Excellent

"Staff was wonderful..great location with BBQ restaurant next door"

Holiday Inn Express & Suites St Louis Airport by IHG

10/10 Excellent

"Every thing was perfect. The staff was VERY attentive, rooms were very comfortable, the bed was the most comfortable and the breakfast was more than enough. Absolutely would stay here again."

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

10/10 Excellent

"They accommodated me with a late check out. I appreciate that!"

Hilton St. Louis Airport

10/10 Excellent

"Service"

Comfort Inn & Suites Hazelwood - St. Louis

10/10 Excellent

"Best time ever"

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

You can enjoy some culture when you stop by Blacks in Flight Mural in St. Louis. Experience the area's fascinating museums and acclaimed art scene.

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Payne-Gentry Historical House

7.0/10 (37 reviews)

Find out about the history of Bridgeton when you spend time at Payne-Gentry Historical House. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Blanche M. Touhill Performing Arts Center

10.0/10 (2 reviews)

Enjoy an outing to Blanche M. Touhill Performing Arts Center during your stay in St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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Old St. Ferdinand Shrine

2.0/10 (1 review)

You can spend time exploring the galleries in Old St. Ferdinand Shrine in Florissant. Experience the great live music and acclaimed theater scene in this family-friendly area.

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St. Louis Mercantile Library

St. Louis Mercantile Library is just one of the places to see in Normandy, so why not enjoy the other things to explore during your travels? Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

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St. Louis Car Museum

9.2/10 (5 reviews)

You can spend time exploring the galleries in St. Louis Car Museum during your travels in Overland. Experience the acclaimed theater scene and great live music in this family-friendly area.

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St. Louis Kaplan Feldman Holocaust Museum

6.0/10 (1 review)

You can spend time studying the exhibits at St. Louis Kaplan Feldman Holocaust Museum during your travels in St. Louis. Experience the great live music and acclaimed theater scene in this family-friendly area.

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New Jewish Theatre

6.0/10 (1 review)

You can make plans for a show at New Jewish Theatre during your trip to St. Louis. Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Frequently asked questions

What's the area like around James S. McDonnell Prologue Room?

James S. McDonnell Prologue Room is located in a welcoming area of St. Louis known for its array of dining options and sporting events. You'll find 116 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay close to James S. McDonnell Prologue Room?

Renaissance St. Louis Airport Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an indoor pool. It's located 1.2 mi (2 km) from James S. McDonnell Prologue Room. Other good choices within a few miles include Pear Tree Inn St. Louis Airport and Drury Inn & Suites St. Louis Airport.

How many hotels will I find near James S. McDonnell Prologue Room?

Expedia has 116 hotels and other accommodations a few miles from James S. McDonnell Prologue Room.

If I need to cancel the hotel reservation for my stay near James S. McDonnell Prologue Room, will I receive a refund?

Yes, most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best options available near James S. McDonnell Prologue Room.

Where can I learn more about changing or cancelling my trip in the area near James S. McDonnell Prologue Room?

For more details about picking new dates or cancelling your stay near James S. McDonnell Prologue Room, go to https://www.expedia.com/service/.

What can I see and do near James S. McDonnell Prologue Room?

You'll want to browse the exhibits at Payne-Gentry Historical House and St. Louis Car Museum. Create some family memories at Par-Tee Recreation Center and Blanche M. Touhill Performing Arts Center. Old St. Ferdinand Shrine and St. Louis Mercantile Library are both worth a visit while you're checking out the area.

Find hotels near James S. McDonnell Prologue Room, St. Louis from ₩98,915

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Be picky

Check prices for these dates

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Our top choices for James S. McDonnell Prologue Room hotels

1. Wingate by Wyndham St. Louis Airport

2. Pear Tree Inn St. Louis Airport

3. Drury Inn & Suites St. Louis Airport

4. Hyatt Select St. Louis Airport

5. Hampton Inn By Hilton St Louis Airport

6. Holiday Inn Express & Suites St Louis Airport by IHG

7. Renaissance St. Louis Airport Hotel

8. Marriott St. Louis Airport

9. DoubleTree by Hilton St. Louis Airport

10. Hilton St. Louis Airport

11. Quality Inn Florissant - St Louis

12. HomeTowne Studios by Red Roof St. Louis - Airport/ N Lindbergh

13. Welcome Suites Hazelwood

14. Quality Inn Saint Louis Airport

15. Drury Plaza Hotel St. Louis St. Charles

16. Drury Plaza Hotel St. Louis Brentwood

17. Hampton Inn & Suites St. Louis at Forest Park

18. Courtyard by Marriott St. Louis Brentwood

19. The Knight Center at Washington University

20. Residence Inn By Marriott St. Louis Clayton

Compare popular hotels close to James S. McDonnell Prologue Room

Top James S. McDonnell Prologue Room Hotel Reviews

Hampton Inn By Hilton St Louis Airport

Renaissance St. Louis Airport Hotel

Pear Tree Inn St. Louis Airport

Drury Inn & Suites St. Louis Airport

Wingate by Wyndham St. Louis Airport

Holiday Inn Express & Suites St Louis Airport by IHG

La Quinta Inn & Suites by Wyndham St. Louis Hazelwood/ North

Hilton St. Louis Airport

Comfort Inn & Suites Hazelwood - St. Louis

Other attractions near James S. McDonnell Prologue Room

Blacks in Flight Mural

Payne-Gentry Historical House

Blanche M. Touhill Performing Arts Center

Old St. Ferdinand Shrine

St. Louis Mercantile Library

St. Louis Car Museum

St. Louis Kaplan Feldman Holocaust Museum

New Jewish Theatre

Frequently asked questions