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Compare 3,663 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa María hotels

Mood Matuna Hotel Cartagena

4.0 star property
9.0 out of 10, Wonderful, (349)
"Great location, good price , clean , friendly staff"
The price is ₩139,825
₩139,825 total
Sep 6 - Sep 7
Mood Matuna Hotel Cartagena

Hotel Voilá Centro Histórico

4.0 star property
9.2 out of 10, Wonderful, (679)
"Great staff, room and location"
The price is ₩246,636
₩246,636 total
Aug 26 - Aug 27
Hotel Voilá Centro Histórico

Bastión Luxury Hotel

4.5 star property
9.6 out of 10, Exceptional, (1000)
"Beautiful hotel and amazing service"
The price is ₩364,138
₩364,138 total
Sep 7 - Sep 8
Bastión Luxury Hotel

Osh Hotel Cartagena

3.5 star property
9.6 out of 10, Exceptional, (615)
"Great hotel and great location "
The price is ₩342,499
₩342,499 total
Aug 25 - Aug 26
Osh Hotel Cartagena

Sofitel Baru Calablanca

5.0 star property
9.4 out of 10, Exceptional, (551)
"This resort is "
The price is ₩390,402
₩390,402 total
Sep 20 - Sep 21
Sofitel Baru Calablanca

Movich Hotel Cartagena de Indias

4.0 star property
9.4 out of 10, Exceptional, (531)
"Beautiful property and conveniently located with a great, great breakfast."
The price is ₩367,661
₩367,661 total
Sep 19 - Sep 20
Movich Hotel Cartagena de Indias

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

4.0 star property
9.4 out of 10, Exceptional, (215)
"This is a nice Boutique Hotel, and I highly recommend it for couples. "
The price is ₩453,370
₩453,370 total
Sep 14 - Sep 15
Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Hotel Fenix Beach Cartagena

4.0 star property
8.8 out of 10, Excellent, (528)
"Amazing stay! We came as a family of 4 and really enjoy our time. So pleased about the service and the friendliness of the staff. Food and drink choices/taste were excellent. Room confort, beyond expected. Definitely recommended it. Looking forward to our next trip."
The price is ₩195,174
₩199,340 total
Sep 2 - Sep 3
Hotel Fenix Beach Cartagena

Cinco Quintas Hotel Boutique

4.0 star property
9.4 out of 10, Exceptional, (199)
"Loved the hotel rooms super spacious and comfy. The decor was stunning and the Staff 10/10. Excellent location walked to every restaurant and shopping boutiques."
The price is ₩316,599
₩316,599 total
Aug 26 - Aug 27
Cinco Quintas Hotel Boutique

Getsemani Cartagena Luxury Hotel

3.5 star property
8.8 out of 10, Excellent, (970)
"Clean rooms , AC , everyone was so nice and helpful ."
The price is ₩117,089
₩117,089 total
Aug 29 - Aug 30
Getsemani Cartagena Luxury Hotel

Casa Emma Hotel Boutique

2.5 star property
8.8 out of 10, Excellent, (91)
"Great property, updated with a rustic style. The bed was awesome! Only improvements would be to the hot water heater on the shower as it is hard to regulate the temperature of the water."
The price is ₩105,548
₩105,548 total
Aug 23 - Aug 24
Casa Emma Hotel Boutique

Hotel Boutique Santo Toribio

4.0 star property
9.2 out of 10, Wonderful, (308)
"Food breakfast is a little limited, eggs, pancakes,fruit, coffee and juice Personal very nice and very attentive to your needs Clean bed, and room Property is nice and well kept Safe to walk after midnight, they come and open the door for you if you arrive late "
The price is ₩264,943
₩264,943 total
Sep 5 - Sep 6
Hotel Boutique Santo Toribio

Delirio

3.5 star property
8.4 out of 10, Very Good, (441)
"Great location and personnel was friendly and helpful "
The price is ₩230,701
₩230,701 total
Sep 20 - Sep 21
Delirio

Charleston Santa Teresa Cartagena

5.0 star property
9.4 out of 10, Exceptional, (736)
"Great location, staff and property"
The price is ₩320,310
₩320,310 total
Sep 2 - Sep 3
Charleston Santa Teresa Cartagena

Casa Claver Loft Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (546)
"We loved Casa Claver. The room were very spacious, modern and clean, and the services by Benjamin and Zindy were spot on. The location was also great; very close to everything. I highly recommend it if you like staying in boutique hotels. "
The price is ₩210,893
₩210,893 total
Sep 16 - Sep 17
Casa Claver Loft Boutique Hotel

Hotel Don Pedro de Heredia

3.5 star property
8.4 out of 10, Very Good, (706)
"Good"
The price is ₩124,974
₩124,974 total
Aug 23 - Aug 24
Hotel Don Pedro de Heredia

Santa Catalina Hotel

4.0 star property
9.2 out of 10, Wonderful, (963)
"Great hotel! The hotel is located in a perfect area."
The price is ₩272,286
₩272,286 total
Sep 20 - Sep 21
Santa Catalina Hotel

Hotel AT THE PARK

2.5 star property
8.8 out of 10, Excellent, (105)
"Great stay Outside very loud inside hotel nice and quiet."
The price is ₩110,653
₩110,653 total
Sep 13 - Sep 14
Hotel AT THE PARK

Hotel Casa Canabal by Faranda Boutique

4.0 star property
9.2 out of 10, Wonderful, (466)
"Service was incredible "
The price is ₩191,626
₩191,626 total
Sep 22 - Sep 23
Hotel Casa Canabal by Faranda Boutique

Privado Designer Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (98)
"Great place "
The price is ₩199,131
₩199,131 total
Aug 23 - Aug 24
Privado Designer Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa María

Check out Marbella Beach and Las Americas International Convention Center—just a couple of the sights around Santa María.

Top Santa María Hotel Reviews

Frequently asked questions

Where is the best place to stay in Santa María?

Located 3.9 mi (6.3 km) from the heart of Santa María, InterContinental Cartagena De Indias by IHG is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Hilton Cartagena and Hyatt Regency Cartagena. See all available top hotels, or vacation rentals in Santa María.

What's the top vacation rental that Santa María has to offer?

Hotel Casa Noi: This vacation home rental near Santa María is located in the historical district and has an outdoor pool, a rooftop terrace, and air-conditioning to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa María.

If I need to cancel my hotel reservation in Santa María, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa María.

Where can I learn more about changing or cancelling my trip to Santa María?

To access more information about rescheduling or cancelling your trip to Santa María, head over to our customer service page.

What are some hotels with pools in Santa María?

InterContinental Cartagena De Indias by IHG: Hotel, 1-minute walk from Bocagrande Beach. Features a children's pool, an outdoor pool, and a full-service spa. Hilton Cartagena and Hyatt Regency Cartagena are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa María.

How is it staying in Santa María?

Visitors are sure to enjoy all that Santa María has to offer. In Santa María, there are 10 hotels and other accommodations to choose from. Find out more about Santa María.

What are the top places to visit in Santa María?

Places to visit in the wider area include Marbella Beach, Las Americas International Convention Center, and La Boquilla Beach. You'll also find Mall Plaza El Castillo and Walls of Cartagena in the area. Check out what more to see and do in Expedia's Santa María guide.

What's the weather like in Santa María?

The hottest months are usually February and March with an average temp of 82°F, while the coldest months are January and February with an average of 82°F. The rainiest months in Santa María are October, November, August, and September, with each month seeing an average of 11 inches of rainfall.