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Compare 1,775 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis Chesterfield

AC Hotel St. Louis Clayton
AC Hotel St. Louis Clayton

Best Western Plus St. Louis Airport Hotel
Best Western Plus St. Louis Airport Hotel

Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport

Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station

Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
Great weekend hotel deals in St. Louis, MO
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River City Casino & Hotel
Where to stay in St. Louis

Downtown St. Louis
Head to the heart of the largest city in Missouri for its cultural hotspots, nightlife and a colossal monument that towers over the Mississippi River.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
St. Louis and related destinations
Stroll under the Gateway Arch, explore a plethora of museums and enjoy an outstanding music scene initiated by natives Chuck Berry and Miles Davis.

More cheap stays in St. Louis
More cheap stays in St. Louis

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Stay near popular St. Louis attractions
Stay near popular St. Louis attractions

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed art scene or attend a baseball game.
Recent reviews of St. Louis hotels
Recent reviews of St. Louis hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
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Explore a world of travel with Expedia
Hotels in St. Louis Neighborhoods
- Hotels in Downtown St. Louis
- Hotels in Clayton
- Hotels in Central West End
- Hotels in Creve Coeur
- Hotels in Soulard
- Hotels in St. Charles Historic District
- Hotels in The Hill
- Hotels in Ladue
- Hotels in University City
- Hotels in Lafayette Square
- Hotels in Cahokia
- Hotels in Lindenwood Park
- Hotels in LaSalle Park
Stay near popular St. Louis attractions
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