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Our top choices for Downtown St. Louis hotels

Comfort Inn & Suites Saint Louis Lafayette Square
Comfort Inn & Suites Saint Louis Lafayette Square
Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
Grand Center Inn
Grand Center Inn
Marriott St. Louis Grand
Marriott St. Louis Grand
St. Louis Union Station Hotel, Curio Collection by Hilton
St. Louis Union Station Hotel, Curio Collection by Hilton
Live by Loews - St.Louis
Live by Loews - St.Louis
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
Hilton St. Louis at the Ballpark
Hilton St. Louis at the Ballpark
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
21C Museum Hotel St Louis
21C Museum Hotel St Louis
Courtyard by Marriott St. Louis Downtown/Convention Center
Courtyard by Marriott St. Louis Downtown/Convention Center
The Westin St. Louis
The Westin St. Louis
Hotel Indigo St. Louis - Downtown by IHG
Hotel Indigo St. Louis - Downtown by IHG
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. Louis
3323: Uptown Elegant Escape by JZ Vacation Rentals
3323: Uptown Elegant Escape by JZ Vacation Rentals
Drury Inn & Suites St. Louis Union Station
Drury Inn & Suites St. Louis Union Station
Hilton Pennywell St. Louis at the Arch
Hilton Pennywell St. Louis at the Arch
Hotel Saint Louis, Autograph Collection
Hotel Saint Louis, Autograph CollectionWhere to stay in Downtown St. Louis

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Soulard
You'll enjoy the bars and churches in Soulard. You might want to make time for a stop at Anheuser-Busch Brewery or Soulard Farmer's Market.
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