Downtown San Francisco Vacations
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Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Fisherman's Wharf
1 out of top 10 points of interest in this area
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Mission District
Mission District is a destination travelers like for its bars, and you might hop aboard the metro at 16th Street Mission Station or 24th Street Mission Station to explore sights like SOMA Pilipinas.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
₩203,794
₩239,860 total
Sep 20 - Sep 21
includes taxes & fees
9/10 Wonderful! (6,264 reviews)
"Had a great stay" Staff were all awsome and friendly....! Great location to UCSF medical facilities.." Wish we had more time to stay a coupkle more days. Parking is great to........A+++++++++++"
Reviewed on Sep 9, 2026
Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
₩234,136
₩275,567 total
Oct 2 - Oct 3
includes taxes & fees
8.6/10 Excellent! (1,680 reviews)
"Clean room and nice staff"
Reviewed on Sep 9, 2026
The Pickwick Hotel
85 5th St San Francisco CA
Fully refundableReserve now, pay when you stay
₩138,363
₩162,576 total
Oct 4 - Oct 5
includes taxes & fees
7.8/10 Good! (1,517 reviews)
"Great experience! Will be booking here again"
Reviewed on Sep 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Downtown San Francisco vacation package cost?
Starting from only , a package is your gateway to affordable travel. Put together your Downtown San Francisco getaway by choosing from our extensive range of flights, hotels and rental cars.
How do I get a cheap travel package to Downtown San Francisco?
If you love getting a great deal, combine your bookings into a Downtown San Francisco vacation package. Whether you're searching for hotels, flights, day tours or rental cars, you can book everything in one place. You'll have loads of choice at your fingertips too. Expedia has more than 550 air carriers and 1,000,000 hotels throughout the world to select from. Fly with who you prefer, stay anywhere you like and save a bundle — now that's the ideal vacation!
Where should I stay in Downtown San Francisco?
Vacationers come from all over to experience Pier 39 and Alcatraz Island in Downtown San Francisco. Book yourself a room near these top attractions and visit them at your leisure.
What are the top hotels in Downtown San Francisco?
If this will be your first time in Downtown San Francisco, lock in a room at Sonder at Found Union Square or Globe Hotel San Francisco SoMa. Both hotels offer comfortable beds and are favorites among many savvy travelers.
How far in advance should I book my Downtown San Francisco vacation?
Savvy travelers often book as early as possible. You can generally look up international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, there's no need to worry. Budget prices occasionally become available just weeks before departure dates.
What does an Expedia Downtown San Francisco travel package include?
Rental cars, flights and hotels, or any combination of them — it's totally up to you. Whether you're venturing to Downtown San Francisco on a family road trip or adventuring solo, there's a package to suit every style and budget. Once you've made your booking, why not add on a few tours or activities?
What should I know before booking a Downtown San Francisco travel package?
When you book your flights, hotels and car rentals together, you'll walk away with amazing discounts. Whether you're organizing a beach escape in a villa or want to stay in a fancy hotel in the city, Expedia will make it happen for less.
Can I choose my airline with a Downtown San Francisco Expedia vacation package?
Expedia offers access to more than 550 partner airlines globally, so you definitely can. Simply choose the carrier you want and put together the perfect Downtown San Francisco trip.
If I'm not able to travel, can I cancel my Downtown San Francisco vacation package?
Your situation can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Downtown San Francisco vacation package at no cost within 24 hours of booking. For older bookings, you can still cancel or make changes, but your car rental company, airline or hotel may charge a fee. Looking for more information? Visit our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
Stay near popular Downtown San Francisco attractions
Moscone Convention Center
8.2/10 (2,926 reviews)
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Oracle Park
8.8/10 (7,978 reviews)
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
Chase Center
8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
Union Square
8.6/10 (1,277 reviews)
You can search for that perfect souvenir at Union Square during your trip to San Francisco. Discover the top-notch restaurants and fascinating museums in this walkable area.
Embarcadero Center
9.2/10 (94 reviews)
During your visit to San Francisco, you can browse for the perfect souvenirs at Embarcadero Center. Amble around this vibrant area's Chinatown or experience its acclaimed theater scene.
San Francisco Museum of Modern Art
9.0/10 (2,422 reviews)
Displaying artworks from Frida Kahlo to Andy Warhol, this museum of modern and contemporary art is one of the largest of its kind in the United States.
Ferry Building
9.0/10 (348 reviews)
During your trip to San Francisco, you can enjoy retail therapy at Ferry Building. Discover the fascinating museums and notable monuments in this vibrant area.
Bill Graham Civic Auditorium
8.4/10 (45 reviews)
You can get tickets for a performance at Bill Graham Civic Auditorium during your trip to San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.