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Compare 3,663 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Santa María hotels

Varanasi Hotel Boutique

3.0 star property
9.2 out of 10, Wonderful, (560)
"The breakfast was amazing! Beautiful pool! The staff was very polite and helpful."
The price is ₩112,107
₩112,107 total
Aug 25 - Aug 26
Varanasi Hotel Boutique

Wyndham Garden Cartagena

3.5 star property
8.8 out of 10, Excellent, (1336)
"Excellent staff and convenient location , close to the airport and beach "
The price is ₩143,892
₩143,892 total
Aug 25 - Aug 26
Wyndham Garden Cartagena

Hotel Ayenda Cartagena Blue 1804

2.0 star property
8.0 out of 10, Very Good, (98)
"Everything well"
The price is ₩40,328
₩40,328 total
Aug 25 - Aug 26
Hotel Ayenda Cartagena Blue 1804

Hotel Summer Frente Al Mar

3.0 star property
8.0 out of 10, Very Good, (457)
"Staff was very friendly, and helpful! Would stay here again."
The price is ₩108,036
₩108,036 total
Aug 25 - Aug 26
Hotel Summer Frente Al Mar

Hotel Fenix Beach Cartagena

4.0 star property
8.8 out of 10, Excellent, (528)
"Amazing stay! We came as a family of 4 and really enjoy our time. So pleased about the service and the friendliness of the staff. Food and drink choices/taste were excellent. Room confort, beyond expected. Definitely recommended it. Looking forward to our next trip."
The price is ₩193,935
₩198,074 total
Sep 2 - Sep 3
Hotel Fenix Beach Cartagena

Sofitel Baru Calablanca

5.0 star property
9.4 out of 10, Exceptional, (552)
"This resort is "
The price is ₩386,019
₩386,019 total
Sep 20 - Sep 21
Sofitel Baru Calablanca

Holiday Inn Express Cartagena Manga by IHG

3.5 star property
8.6 out of 10, Excellent, (200)
"Great place to stay"
The price is ₩148,043
₩148,043 total
Aug 29 - Aug 30
Holiday Inn Express Cartagena Manga by IHG

Hotel Ayenda Casa Cano 1805

3.0 star property
8.0 out of 10, Very Good, (182)
"Good hotel for the price"
The price is ₩38,834
₩38,834 total
Aug 25 - Aug 26
Hotel Ayenda Casa Cano 1805

Radisson Cartagena Ocean Pavillion Hotel

4.5 star property
8.8 out of 10, Excellent, (1001)
"This property was incredibly and the staff was amazing."
The price is ₩184,345
₩184,345 total
Aug 29 - Aug 30
Radisson Cartagena Ocean Pavillion Hotel

Townhouse Boutique Hotel

4.0 star property
9.2 out of 10, Wonderful, (350)
"Very nice hotel close to everything. "
The price is ₩179,611
₩179,611 total
Sep 17 - Sep 18
Townhouse Boutique Hotel

Casa Noa Colonial Rooms

2.5 star property
9.4 out of 10, Exceptional, (143)
"The room was comfortable and the area was very convenient !"
The price is ₩95,999
₩95,999 total
Sep 1 - Sep 2
Casa Noa Colonial Rooms

Casa Claver Loft Boutique Hotel

4.0 star property
9.6 out of 10, Exceptional, (546)
"We loved Casa Claver. The room were very spacious, modern and clean, and the services by Benjamin and Zindy were spot on. The location was also great; very close to everything. I highly recommend it if you like staying in boutique hotels. "
The price is ₩209,554
₩209,554 total
Sep 16 - Sep 17
Casa Claver Loft Boutique Hotel

Movich Hotel Cartagena de Indias

4.0 star property
9.4 out of 10, Exceptional, (531)
"Beautiful property and conveniently located with a great, great breakfast."
The price is ₩365,327
₩365,327 total
Sep 19 - Sep 20
Movich Hotel Cartagena de Indias

Las Americas Casa de Playa

4.0 star property
8.8 out of 10, Excellent, (1002)
"Great place ! A nice resort the food is amazing and staff very friendly "
The price is ₩210,573
₩210,573 total
Sep 20 - Sep 21
Las Americas Casa de Playa

Santa Catalina Hotel

4.0 star property
9.2 out of 10, Wonderful, (963)
"Great hotel! The hotel is located in a perfect area."
The price is ₩264,038
₩264,038 total
Sep 20 - Sep 21
Santa Catalina Hotel

Hotel Estelar Playa Manzanillo

4.0 star property
8.2 out of 10, Very Good, (938)
"Would stay again "
The price is ₩378,058
₩378,058 total
Sep 21 - Sep 22
Hotel Estelar Playa Manzanillo

Hotel Casa Lola Deluxe Gallery

4.0 star property
9.0 out of 10, Wonderful, (475)
"Great location, this hotel did not disappoint! "
The price is ₩223,304
₩223,304 total
Aug 26 - Aug 27
Hotel Casa Lola Deluxe Gallery

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

4.5 star property
9.2 out of 10, Wonderful, (283)
"Friendly and engaging staff. Great location. And plan to stay there again on my next trip."
The price is ₩244,064
₩244,064 total
Sep 17 - Sep 18
Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

Hotel Las Americas Torre del Mar

4.5 star property
9.0 out of 10, Wonderful, (1002)
"Best hotel for family with kids in Cartagena "
The price is ₩261,903
₩261,903 total
Sep 20 - Sep 21
Hotel Las Americas Torre del Mar

Mood Matuna Hotel Cartagena

4.0 star property
9.0 out of 10, Wonderful, (349)
"Great location, good price , clean , friendly staff"
The price is ₩140,100
₩140,100 total
Sep 8 - Sep 9
Mood Matuna Hotel Cartagena
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa María

Check out Marbella Beach and Las Americas International Convention Center—just a couple of the sights around Santa María.

Top Santa María Hotel Reviews

Frequently asked questions

Where is the best place to stay in Santa María?

Located 3.9 mi (6.3 km) from the heart of Santa María, InterContinental Cartagena De Indias by IHG is a top choice for your stay based on our traveler data. Two other choices for your stay in the area are Hilton Cartagena and Hyatt Regency Cartagena. See all available top hotels, or vacation rentals in Santa María.

What's the top vacation rental that Santa María has to offer?

Hotel Casa Noi: This vacation home rental near Santa María is located in the historical district and has an outdoor pool, a rooftop terrace, and air-conditioning to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. Make the most of the garden in this rental home to help you unwind. See all vacation rentals in Santa María.

If I need to cancel my hotel reservation in Santa María, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa María.

Where can I learn more about changing or cancelling my trip to Santa María?

To access more information about rescheduling or cancelling your trip to Santa María, head over to our customer service page.

What are some hotels with pools in Santa María?

InterContinental Cartagena De Indias by IHG: Hotel, 1-minute walk from Bocagrande Beach. Features a children's pool, an outdoor pool, and a full-service spa. Hilton Cartagena and Hyatt Regency Cartagena are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa María.

How is it staying in Santa María?

Visitors are sure to enjoy all that Santa María has to offer. In Santa María, there are 10 hotels and other accommodations to choose from. Find out more about Santa María.

What are the top places to visit in Santa María?

Places to visit in the wider area include Marbella Beach, Las Americas International Convention Center, and La Boquilla Beach. You'll also find Mall Plaza El Castillo and Walls of Cartagena in the area. Check out what more to see and do in Expedia's Santa María guide.

What's the weather like in Santa María?

The hottest months are usually February and March with an average temp of 82°F, while the coldest months are January and February with an average of 82°F. The rainiest months in Santa María are October, November, August, and September, with each month seeing an average of 11 inches of rainfall.