Photo by Bill Dillard

Southeast Missouri, Missouri hotel rooms at the Drury Inn & Suites

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Check prices for these dates

Tonight
Nov 11 - Nov 12
Tomorrow
Nov 12 - Nov 13
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

Our top choices for Southeast Missouri Drury Inn & Suites

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Great place to stay!"
United States
Tiffany
The price is ₩126,243
₩145,147 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Sikeston, MO
A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

2. Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
3.0 star property
Hayti
9.2 out of 10, Wonderful, (1,001 reviews)
"The food & drinks were great & the staff was very friendly. Room was very nice."
United States
Cynthia
The price is ₩131,615
₩150,008 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Hayti Caruthersville
A spacious lobby with a reception desk, seating area, and large windows.

3. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is ₩120,938
₩136,631 total
includes taxes & fees
Nov 15 - Nov 16
Drury Inn & Suites Poplar Bluff
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

4. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean, spacious suite, enjoyable kick back and breakfast!"
United States
Mary
The price is ₩120,870
₩136,358 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Cape Girardeau
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

5. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,003 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
The price is ₩107,439
₩113,591 total
includes taxes & fees
Nov 22 - Nov 23
Drury Inn & Suites Jackson MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

A wooden deck with two Adirondack chairs and a hammock.
Tiny Houses of French Village

Tiny Houses of French Village

Tiny Houses of French Village
French Village

10/10 Excellent

I was a great experience loved everything about it
United States
Alisha
Reviewed August 3, 2026
Tiny Houses of French Village