A red train on tracks, palm trees, and modern buildings.

Central San Diego 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Central San Diego 4 Star Hotels

This weekend
Next weekend

Our top choices for Central San Diego 4-star hotels

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,596 reviews)
"Excellent resorts"
United States
christian
The price is ₩356,387
₩463,096 total
includes taxes & fees
Aug 1 - Aug 2
Town and Country San Diego

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1,765 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is ₩401,121
₩461,072 total
includes taxes & fees
Jul 6 - Jul 7
Lafayette Hotel & Club

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2,414 reviews)
"The place was very clean, the staff was very helpful and friendly."
United States
John
The price is ₩344,236
₩395,785 total
includes taxes & fees
Jul 26 - Jul 27
San Diego Marriott La Jolla

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1,715 reviews)
"A great place to stay many things to see and do"
United States
Mauricio
The price is ₩252,722
₩290,492 total
includes taxes & fees
Jul 19 - Jul 20
DoubleTree by Hilton Hotel San Diego - Mission Valley

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,696 reviews)
"The front desk was very helpful."
United States
Frank
The price is ₩261,735
₩300,856 total
includes taxes & fees
Jul 2 - Jul 3
Sheraton Mission Valley San Diego Hotel

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,006 reviews)
"Great place to stay."
United States
ANTHONY
The price is ₩308,197
₩354,257 total
includes taxes & fees
Jul 9 - Jul 10
San Diego Marriott Mission Valley

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.2 out of 10, Very Good, (2,518 reviews)
"Had a great time and treated us very well."
United States
Maura
The price is ₩229,694
₩264,023 total
includes taxes & fees
Jul 5 - Jul 6
Hilton San Diego Mission Valley

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1,944 reviews)
"Great location and very comfortable and spacious hotel room"
United States
Carmen
The price is ₩340,535
₩435,551 total
includes taxes & fees
Jul 9 - Jul 10
Embassy Suites by Hilton San Diego La Jolla

Hyatt Regency La Jolla

Hyatt Regency La Jolla
4.0 star property
University City
9.0 out of 10, Wonderful, (1,001 reviews)
"Our go to hotel whenever we visit the area!"
United States
Maria
The price is ₩333,131
₩439,958 total
includes taxes & fees
Jul 12 - Jul 13
Hyatt Regency La Jolla

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (3,067 reviews)
"Great place to stay!!"
United States
Griffin
The price is ₩262,329
₩301,531 total
includes taxes & fees
Jul 6 - Jul 7
Legacy Resort Hotel & Spa

DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
4.0 star property
Mission Valley
7.2 out of 10, Good, (1,915 reviews)
"They Just need a complementary Breakfast and it’ll be Perfect"
United States
Rene
The price is ₩198,052
₩227,651 total
includes taxes & fees
Jul 5 - Jul 6
DoubleTree by Hilton San Diego - Hotel Circle

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (168 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
The price is ₩217,808
₩297,985 total
includes taxes & fees
Jul 2 - Jul 3
City24 Hotel Little Italy Mission Hills

Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
4.5 star property
Mission Valley
8.8 out of 10, Excellent, (1,000 reviews)
"It was spacious and convenient but it was very dirty"
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Central San Diego

A must-see zoo, seaside views, and top sights from San Diego Zoo to Snapdragon Stadium—discover Central San Diego, a historic destination also famous for its sports teams.

A red train on tracks, palm trees, and modern buildings.

Top Central San Diego Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.

  • Search for the lowest price from ₩227,651

What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.