A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City 4 Star Hotels

Tonight
Aug 23 - Aug 24
Tomorrow
Aug 24 - Aug 25
Next weekend
Aug 28 - Aug 30
In two weeks
Sep 4 - Sep 6

Our top choices for Panama City 4-star hotels

A swimming pool with clear water, a poolside area with lounge chairs, and a building with large windows and doors.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen
United States
Tameka
₩174,615
₩201,223 total
includes taxes & fees
Sep 21 - Sep 22
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
querube
₩254,161
₩279,577 total
includes taxes & fees
Sep 22 - Sep 23
Central Hotel Panama Casco Viejo
A rooftop pool with sun loungers and a city skyline in the background.
A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large flat-screen TV, a desk, a comfortable armchair, a bed, a bedside table, and a view of the city through the window.

3. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Amrit
₩118,488
₩237,046 total
includes taxes & fees
Aug 24 - Aug 25
Waymore Hotel Spa & Casino
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A modern spa area with a hot tub, seating, and a city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.

4. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Mark
₩189,906
₩189,906 total
includes taxes & fees
Sep 5 - Sep 6
Megapolis Hotel Panamá
A buffet with various food items including fruits, juices, and cheeses.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

5. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Khadija
₩135,465
₩149,012 total
includes taxes & fees
Aug 28 - Aug 29
Courtyard by Marriott Panama Metromall
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A resort with a pool, palm trees, and a building with a red roof.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Jerry
₩377,292
₩377,292 total
includes taxes & fees
Aug 24 - Aug 25
Dreams Playa Bonita Panama - All Inclusive
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.

7. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Shereen
₩163,736
₩180,103 total
includes taxes & fees
Sep 6 - Sep 7
Courtyard by Marriott Panama Multiplaza Mall
A reception area with marble reception desks and a sign indicating the reception desk.
A balcony with a view of a swimming pool, palm trees, and city buildings.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.

8. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
Josiah
₩137,197
₩150,917 total
includes taxes & fees
Sep 14 - Sep 15
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A spacious hotel lobby with a central bar area, seating arrangements, and large windows allowing natural light.
A balcony with two wooden chairs, a white balustrade, and a view of boats and palm trees on a calm sea.
A restaurant with a modern interior, featuring black and white patterned chairs, wooden tables, hanging pendant lights, and a menu board on the wall.

9. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United States
amina
₩131,718
₩144,893 total
includes taxes & fees
Sep 6 - Sep 7
Radisson Hotel Panama Canal
A hotel room with a sofa, a coffee table, a TV, and a cabinet.

10. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving

11. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen
United States
Elizabeth
₩150,031
₩165,034 total
includes taxes & fees
Aug 25 - Aug 26
Riande Aeropuerto Hotel & Casino
A modern building with a glass facade, a curved structure, and a flat roof.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.

12. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Diana
₩155,765
₩171,341 total
includes taxes & fees
Sep 13 - Sep 14
Decapolis Hotel Panama City
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
An indoor swimming pool with lounge chairs and a modern interior design.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

13. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Mariah
₩238,210
₩262,032 total
includes taxes & fees
Aug 30 - Aug 31
Las Americas Golden Tower Panama
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

14. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Zaccaria
₩148,422
₩163,264 total
includes taxes & fees
Sep 10 - Sep 11
Novotel Panama City
A buffet with various food items and a decorative plant.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.
A spa area with a hot tub, candles, and a curved bench.

15. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Luis
₩243,213
₩267,534 total
includes taxes & fees
Aug 31 - Sep 1
Sheraton Grand Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A buffet setup with various dishes and utensils.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

16. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Gale
₩223,119
₩245,430 total
includes taxes & fees
Aug 30 - Aug 31
Marriott Panama Hotel
A balcony with wicker chairs and a view of the cityscape.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A rooftop pool area with a view of high-rise buildings in the background.

17. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Bettyanne
₩150,778
₩165,856 total
includes taxes & fees
Aug 28 - Aug 29
Ramada Plaza by Wyndham Panama Punta Pacifica
A restaurant with multiple dining tables, chairs, and a central water feature.
A bar area with multiple seating options, a bar counter, and a fireplace.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.
A historic building with ornate stonework and a balcony with plants.

18. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
United States
Reid
₩440,555
₩484,611 total
includes taxes & fees
Sep 17 - Sep 18
Hotel La Compañía Casco Antiguo
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.
A hotel room with two beds, a sofa, a bench, a TV, and a view of buildings.
A modern conference room with a long table, colorful chairs, and large windows offering a city view.
A modern hotel pool with a glass barrier, surrounded by high-rise buildings and a sunset view.

19. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
San Francisco
United States
Frank David Delgado
₩297,953
₩327,748 total
includes taxes & fees
Sep 11 - Sep 12
Residence Inn by Marriott Panama City
A rooftop pool with a city view, lounge chairs, and a clear sky.
A modern lobby with a curved grey sofa, a round coffee table, and an orange armchair. There are potted plants and a reception desk in the background.
A modern kitchen with a marble countertop, a refrigerator, and a dining area with a table set for two.
A modern lounge area with a bar, seating, and a large window offering a city view.

20. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
Costa del Este
United States
Murietta
₩158,400
₩247,412 total
includes taxes & fees
Aug 25 - Aug 26
Corporate Stays Arcadia | Executive Furnished Apartments
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
₩190,747
₩209,822 total
Sep 15 - Sep 16
includes taxes & fees
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
₩368,464
₩405,310 total
Aug 30 - Aug 31
includes taxes & fees
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
₩467,718
₩514,490 total
Sep 3 - Sep 4
includes taxes & fees
9.8/10 Exceptional! (729 reviews)
Sofitel Legend Casco Viejo, Panama City
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Fuimos 5 dias las cuales fueron increibles el hotel esta en una localizacion previlegiada tiene actividades todos los dias mas el personal muy atento estamos en cantados vamos a regresar muy pronto aca les dejamos unas fotos para q puedan ver"
Jacqueline 4-night trip
Posted 15 hours ago
Central Hotel Panama Casco Viejo
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"Todo estaba súper Lindo y limpio y muy cómodo para el precio creo que estuve súper, pero la única razón por la que no doy las 5 estrellas, es por que el baño, en la zona de la tina estaba llena de moho negro incluso la cortina blanca se le podía ver el Moho negro. Las orillas de la tina también. De resto todo súper chévere"
Luisa 2-night trip
Posted 18 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

10/10 Excellent
"Absolutely loved the view from my room and the staff was very forthcoming and helpful, the breakfast was lovely too, definitely a 10/10 stay."
Mariah 6-night trip
Posted 1 day ago
Las Americas Golden Tower Panama
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"The check in and check out process was efficient and everything went smoothly. The breakfast buffet is a good introduction to local cuisine with a mix of international flavour."
Tricia 5-night trip
Posted 1 day ago
Decapolis Hotel Panama City

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that's popular among Expedia customers. An art gallery and proposal/romance packages are just a couple of its amenities. Travelers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From a swimming pool to a steam room, it offers conveniences that cater to every aspect of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.
  • Search for the lowest price from ₩209,822
What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveler experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City vacation. These types of accommodations generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.