Panama City 5 Stars Hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Panama City 5 Star Hotels
Compare Panama City 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Bella Vista
9.0 out of 10, Wonderful, (4510)
The price is ₩172,519
₩189,771 total
includes taxes & fees
Dec 8 - Dec 9

Waldorf Astoria Panama
Bella Vista
9.0 out of 10, Wonderful, (1001)
The price is ₩249,168
₩274,085 total
includes taxes & fees
Dec 1 - Dec 2

W Panama
Bella Vista
9.0 out of 10, Wonderful, (1001)
The price is ₩254,722
₩280,194 total
includes taxes & fees
Dec 7 - Dec 8

JW Marriott Panama
San Francisco
9.0 out of 10, Wonderful, (1003)
The price is ₩286,562
₩315,218 total
includes taxes & fees
Dec 7 - Dec 8

Renaissance Panama City Hotel
Bella Vista
9.0 out of 10, Wonderful, (84)
The price is ₩168,651
₩185,516 total
includes taxes & fees
Nov 21 - Nov 22

Bristol Panama, a Registry Collection Hotel
Bella Vista
9.2 out of 10, Wonderful, (1000)
The price is ₩231,023
₩254,125 total
includes taxes & fees
Dec 6 - Dec 7

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
9.8 out of 10, Exceptional, (531)
The price is ₩430,232
₩473,255 total
includes taxes & fees
Dec 15 - Dec 16

The Westin Playa Bonita Panama
Veracruz
8.0 out of 10, Very Good, (1000)
The price is ₩241,811
₩265,992 total
includes taxes & fees
Dec 10 - Dec 11
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.

Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is ₩159,928 per night from Nov 26 to Nov 27
₩159,928
₩175,921 total
Nov 26 - Nov 27
includes taxes & fees
8.4/10 Very Good! (2,265 reviews)
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

Top Panama City Hotel Reviews
Hotel Riu Plaza Panama
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
Stay near popular Panama City attractions
More Hotel Options in Panama City
- Adventure Hotels in Panama City
- Beach Hotels in Panama City
- Boutique Hotels in Panama City
- Business Hotels in Panama City
- Casinos in Panama City
- Cheap Hotels in Panama City
- Gay friendly Hotels in Panama City
- Golf Hotels in Panama City
- Green Hotels in Panama City
- Historic Hotels in Panama City
- Hotels with Bars in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with Free Parking in Panama City
- Hotels with Hot Tubs in Panama City
- Hotels with a Pool in Panama City
- Hotels with smoking rooms in Panama City
- Luxury Hotels in Panama City
- Pet-friendly Hotels in Panama City
- Resorts & Hotels with Spas in Panama City
- Romantic Hotels in Panama City
- Winery Hotels in Panama City
More Accommodation Types in Panama City
Explore more hotels
Expedia's Latest Trends
Hotels
Flights
Packages










































