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Find Resorts & Hotels with Spas in Central San Diego, CA

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Check availability on Central San Diego Resorts & Hotels with Spas

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Central San Diego hotels with a spa

A modern bathroom with a shower, a towel rack, and a bench.
A spacious lobby with modern furniture, large windows, and a high ceiling with hanging lights.
A pathway leading to a building labeled "LEGACY Hotel."
A modern interior with wooden panel ceilings, patterned seating, and a central bar area.

1. Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
Mission Valley
  • Indulge in a serene escape at this upscale hotel with a full-service spa, outdoor pool with free cabanas, and couples massage treatments.
₩231,045
₩265,575 total
includes taxes & fees
Oct 25 - Oct 26
Legacy Resort Hotel & Spa
A hotel with a curved entrance, palm trees, and a parking lot.
A bar area with wooden chairs and tables, a bar counter with various bottles, and a sign reading "BEACH BUMS CATER HERE".
A resort with a large swimming pool surrounded by lounge chairs and palm trees.
A lobby with seating areas, a piano, and a reception desk.

2. Handlery Hotel

Handlery Hotel
Mission Valley
  • Surrender to spa treatments and poolside luxury at this hotel with massage rooms and a beautiful heated outdoor pool and hot tub.
₩149,046
₩171,322 total
includes taxes & fees
Oct 7 - Oct 8
Handlery Hotel
An aerial view of a resort with a central swimming pool, palm trees, and a view of the ocean and beach.
A waterfront hotel with a dock, palm trees, and a view of the water.
A living room with a fireplace, a television, a sofa, a chair, a round coffee table, and a view of the ocean through glass doors.
An outdoor dining area with tables and chairs, umbrellas, and string lights against a sunset backdrop.

3. Paradise Point Resort & Spa

Paradise Point Resort & Spa
Mission Bay
  • Immerse in waterfront tranquility with hot stone massages and aromatherapy at this resort spa retreat.
₩278,237
₩390,750 total
includes taxes & fees
Oct 30 - Oct 31
Paradise Point Resort & Spa
A spa room with a bed, a bathtub, and a large window with curtains. There are candles and plants on the windowsill.
A poolside view with a lounge chair, a towel, a tray with a drink and a coconut, and a pool with palm trees in the background.
An outdoor seating area with a canopy, lounge chairs, and a fire pit.
A spacious lobby with a high ceiling, large windows, and a view of palm trees.

4. San Diego Mission Bay Resort

San Diego Mission Bay Resort
Mission Bay
  • Unwind at this bay-view resort offering garden massages, poolside lounging, and a rejuvenating full-service spa retreat.
₩293,789
₩408,635 total
includes taxes & fees
Oct 31 - Nov 1
San Diego Mission Bay Resort
A hotel room with a large bed, a desk, a chair, a painting, and a view of the city.
A spacious lobby with a round table, blue benches, a large painting, and a view of the outdoors.
A hotel entrance with a covered walkway, palm trees, and a parking area.
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and greenery.

5. Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
National City
  • Indulge in bay-side spa services and hot tub relaxation at this tranquil hotel where pampering treatments meet scenic marina views.
₩203,879
₩224,664 total
includes taxes & fees
Oct 29 - Oct 30
Best Western Plus Marina Gateway Hotel
A spacious lobby with a reception desk, seating area, and a stone wall.
A marina with wooden tables and chairs, umbrellas, and a view of boats and city lights in the background.
A canal lined with palm trees and a row of buildings with balconies.
A resort with two-story buildings, balconies, and a pool area.

6. Humphreys Half Moon Inn

Humphreys Half Moon Inn
Point Loma
  • Escape to this bayfront sanctuary with deep-tissue massages, a serene hot tub, and an outdoor pool for complete relaxation.
₩226,714
₩287,430 total
includes taxes & fees
Oct 25 - Oct 26
Humphreys Half Moon Inn
A person sitting by a pool with a tiled floor and a marble wall.
A modern lounge area with leather seating, a central fire feature, and geometric patterned railings.
A modern hotel with a prominent entrance, multiple floors, and a landscaped area with palm trees and a bridge.
A modern lounge area with dark-toned seating, a central coffee table, and a stone accent wall.

7. Sycuan Casino Resort

Sycuan Casino Resort
El Cajon
  • Escape to a luxurious mountain retreat with 10 treatment rooms and outdoor pools, where hot stone massages and aromatherapy await.
₩116,711
₩144,480 total
includes taxes & fees
Oct 15 - Oct 16
Sycuan Casino Resort
A spacious lobby with a reception desk, seating area, and artwork on the walls.
A resort pool with a lazy river, palm trees, and a view of the ocean.
A marina with boats docked, a covered outdoor dining area with red chairs and tables, and a view of the marina in the background.
A hotel entrance with a covered walkway, palm trees, and a modern building in the background.

8. Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
Mission Bay
  • Experience coastal tranquility at this spa hotel with bay views, heated pools, and waterslides.
₩283,057
₩396,333 total
includes taxes & fees
Oct 28 - Oct 29
Hyatt Regency Mission Bay Spa and Marina
A woman in a floral swimsuit stepping out of a spa area with a hot tub, a lounge chair, and a sign indicating an outdoor terrace.
A couple dining outdoors at a table with a fire feature, in front of a classical building with arches.
A cozy lounge area with a fireplace, comfortable seating, and large windows offering a view of the outdoors.
A pool area with lounge chairs and umbrellas, surrounded by palm trees and stone columns.

9. Fairmont Grand Del Mar

Fairmont Grand Del Mar
Carmel Valley
  • Escape to a Mediterranean spa sanctuary with 11 luxurious treatment rooms and four outdoor pools for ultimate rejuvenation.
₩936,898
₩1,185,441 total
includes taxes & fees
Oct 18 - Oct 19
Fairmont Grand Del Mar
A hallway with a wooden ceiling, a potted plant, a sofa with orange cushions, and a fireplace.
A hotel with a water feature, stone steps, and balconies with lights.
A balcony with wicker furniture, a view of the ocean, and palm trees.
A balcony with wicker furniture, a stone building, and a view of the ocean and golf course.

10. Pantai Inn

Pantai Inn
Village of La Jolla
  • Oceanfront wellness sanctuary provides calming massage therapies and a garden terrace, perfect for unwinding after a day by La Jolla Cove.
₩426,530
₩518,694 total
includes taxes & fees
Nov 2 - Nov 3
Pantai Inn
View all properties

Choose what matters most at spa hotels in Central San Diego

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Central San Diego Hotel Reviews

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla

8/10 Good
"The property was good and convenient. The food included with breakfast and afternoon reception could be better. Same for the restaurant in the hotel."
Victoria 1-night trip
Posted 2 hours ago
Embassy Suites by Hilton San Diego La Jolla
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"Clean room"
Brooklyn 2-night trip
Posted 2 hours ago
The Alcala Hotel Mission Valley/Seaworld
Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA

10/10 Excellent
"Everything was excellent from the staff, rooms, location. Food at their bar n grill restaurant was extremely good. Would stop there just for the food lol. But overall, location felt safe and staff was very friendly and rooms were super clean."
Jackeline 1-night trip
Posted 3 hours ago
Country Inn & Suites by Radisson, San Diego North, CA
Handlery Hotel

Handlery Hotel

8/10 Good
"The room was dusty and had lots of spiderwebs the patio/ balcony was dirty full of leaves the carpet was not vacuumed and the bathroom tub was rusty"
Daniela 2-night trip
Posted 5 hours ago
Handlery Hotel
Best Western Seven Seas

Best Western Seven Seas

10/10 Excellent
"Great price, for a last minute stay. Definitely coming back to this location every time I travel to San Diego."
Mark 1-night trip
Posted 6 hours ago
Best Western Seven Seas
Ramada Suites by Wyndham San Diego/Hotel Circle Area

Ramada Suites by Wyndham San Diego/Hotel Circle Area

8/10 Good
"I think that I like about staying at the Ramada by Wyndham was the breakfast they have from 6 to 930. The only bad review I have for the Ramada is I guess they had a sewage bus open inside the motel and there was a foul stench in the lobby area throughout the whole time of our stay. I just think they could did a better job of letting the the guest know about the smell and just instead of having the guest to deal with the smell, especially the ones on the first floor other than that my day was was great along with my wife"
Moses 3-night trip
Posted 6 hours ago
Ramada Suites by Wyndham San Diego/Hotel Circle Area
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

10/10 Excellent
"I got a bottle of Diet Coke from the vending machine, it didn’t show the price. It turned out to be $10 on my credit card transaction."
Jennifer 7-night trip
Posted 10 hours ago
Days Inn by Wyndham San Diego Hotel Circle
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

10/10 Excellent
"We only stayed 1 night, the room was big and clean . Perfect for us"
Carmen 1-night trip
Posted 10 hours ago
The Atwood Hotel San Diego - SeaWorld/Zoo
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

8/10 Good
"Convenient location. Quiet rooms."
Donald 1-night trip
Posted 13 hours ago
Hilton San Diego Mission Valley

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