Central San Diego 4 Stars Hotels

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Our top choices for Central San Diego 4-star hotels

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1438)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is ₩161,956
₩186,160 total
includes taxes & fees
Jan 3 - Jan 4, 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.0 out of 10, Very Good, (2263)
"Loved the easy check in process via the app! "
United States
Larizza
The price is ₩176,546
₩202,931 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hilton San Diego Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2942)
"Great boutique hotel!!"
United States
Maksim
Legacy Resort Hotel & Spa

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1367)
"Amazing hotel, great staff and awesome food!"
United States
michael
The price is ₩330,140
₩378,835 total
includes taxes & fees
Dec 30 - Dec 31
Lafayette Hotel & Club

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1686)
"Great hotel, close to shops, freeway and restaurants. "
United States
Esteban
The price is ₩194,624
₩223,710 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Sheraton Mission Valley San Diego Hotel

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1800)
"Really enjoyed the included breakfast and complimentary happy hour. Rooms were clean. Staff was very nice. "
United States
Maureen
The price is ₩265,986
₩305,738 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Embassy Suites by Hilton San Diego La Jolla

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1002)
"Staff was polite , room service amazing "
Canada
Francois
The price is ₩214,807
₩246,910 total
includes taxes & fees
Jan 4 - Jan 5, 2026
San Diego Marriott Mission Valley

Hyatt Regency La Jolla

Hyatt Regency La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1008)
"Check in was great, employees were so nice"
United States
Noel
The price is ₩218,844
₩304,826 total
includes taxes & fees
Dec 30 - Dec 31
Hyatt Regency La Jolla

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2203)
"We had a great stay! Everything was clean and the staff was phenomenal!! "
United States
Mattie
The price is ₩223,428
₩257,105 total
includes taxes & fees
Jan 10 - Jan 11, 2026
San Diego Marriott La Jolla

DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
4.0 star property
Mission Valley
7.4 out of 10, Good, (1784)
"Great staff and amenities "
United States
Damaja
The price is ₩176,546
₩202,931 total
includes taxes & fees
Jan 4 - Jan 5, 2026
DoubleTree by Hilton San Diego - Hotel Circle

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1328)
"Great Resort, the staff were nice"
United States
Aryana
The price is ₩207,094
₩287,798 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Town and Country San Diego

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (108)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills

Residence Inn by Marriott San Diego Mission Valley

Residence Inn by Marriott San Diego Mission Valley
4.5 star property
Mission Valley
8.8 out of 10, Excellent, (1000)
"It was spacious and convenient but it was very dirty"
United States
Kabnne
Residence Inn by Marriott San Diego Mission Valley
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Learn more about Central San Diego

Explore the seaside area of Central San Diego—a zoo, sports teams, and popular sights like San Diego Zoo.

San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584

Top Central San Diego Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Central San Diego?
Expedia can help you easily locate the ideal 4-star hotel for your vacation in Central San Diego. Use our filter tool to tailor your search by things like price, conveniences and hotel star rating and get access to terrific deals in a couple of clicks.

  • Search for the lowest price from ₩186,160

What's the difference between 5-star and 4-star hotels in Central San Diego?
Offering a welcoming guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Central San Diego escape. These kinds of stays generally feature loads of handy amenities that make it easy to unpack and unwind — think complimentary bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with high-end perks and amenities. A personalized service, complimentary toiletries and gourmet dining are typically featured at these plush retreats.
Does Central San Diego have any 4-star all-inclusive resorts?
Finding your dream resort in Central San Diego is as simple as entering your travel dates and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, food, activities and entertainment, or choose a standard 4-star resort in or around this leading destination.