Panama City 5 Stars Hotels

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Check availability on Panama City 5 Star Hotels

Tonight
Dec 31 - Jan 1
Tomorrow
Jan 1 - Jan 2
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Panama City 5-star hotels

Outdoor pool, sun loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4746)
"The rooms were nice and the food was great..great staff!!"
United States
Tffany
The price is ₩175,075
₩192,583 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Riu Plaza Panama
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1003)
"Lovely stay and lovely price. Luxury in Panama "
United States
Kelinde
The price is ₩315,359
₩346,895 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Waldorf Astoria Panama
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1000)
"staff and food are amazing "
Canada
Judy
The price is ₩268,851
₩295,736 total
includes taxes & fees
Jan 30 - Jan 31, 2026
W Panama
4 outdoor pools, free cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is ₩384,584
₩423,042 total
includes taxes & fees
Jan 30 - Jan 31, 2026
JW Marriott Panama
Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is ₩510,396
₩561,436 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Sofitel Legend Casco Viejo, Panama City
Outdoor pool
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1003)
"The restaurant at the pool, Caio Lagazzi, was amazing. The Hilton breakfast was top notch, except that they were a little slow bringing drinks (but to be fair it was Christmas day and they may have been understaffed). "
United States
Elmer
The price is ₩288,052
₩316,857 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hilton Panama
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very Good, (1004)
"Beautiful property and amazing staff"
United States
CARMEN
The price is ₩338,434
₩372,278 total
includes taxes & fees
Jan 9 - Jan 10, 2026
The Westin Playa Bonita Panama
40-inch Smart TV with cable channels, TV
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (102)
"I stayed for nine nights and I enjoyed my time at this hotel I recommend this hotel for several days staff is nice and the hotel is worth it. "
United States
Sharon Isoken
The price is ₩157,855
₩173,641 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Renaissance Panama City Hotel
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1006)
"Great staff, super accommodating. Best place to stay in Panama!"
United States
Sebastian
The price is ₩276,643
₩304,307 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Bristol Panama, a Registry Collection Hotel
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ₩312,040
₩343,244 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very Good, (1001)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Outdoor pool
Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1000)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Panama City.
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama
The price is ₩157,265 per night from Jan 8 to Jan 9
₩157,265
₩172,991 total
Jan 8 - Jan 9, 2026
includes taxes & fees
8.4/10 Very Good! (2,324 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
Panoramic view at the Downtown of Panama City - Panama

Top Panama City Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Great Staff. Wonderful berakfast. Pool guy worked very hard to straighten lounge chairs, bring freah towels, lower umbrella. Room was on 27th floor with fogged over window. So we requested a different room with a view. They accommodated and gave us 31st floor with a great view. Overall a great experience. We took Uber everywhere we needed to go. Was inexpensive to Uber. For day trips old town was our favorite, Anton Hill hike, and the Causway were fun. "
Jacque 5-night trip
Posted 19 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

What are the best 5-star hotels in Panama City?
Bristol Panama, a Registry Collection Hotel, W Panama and Waldorf Astoria Panama are some of the top 5-star hotels in Panama City, based on our guest reviews. These deluxe hotels rate highly for things such as their location, amenities and service standards. Pick your favorite and enjoy the best of it all.
How much does it cost to stay in a 5-star hotel in Panama City?
The amount you pay for a 5-star hotel in Panama City can vary according to when you prefer to travel and how long you plan to be away, among a range of factors. Use our price per night filter and other search tools to find the best rate on a plush stay.

  • Search for the lowest price per night from ₩172,991

What makes a hotel 5 stars in Panama City?
In Panama City, a hotel needs to offer a certain level of high-end conveniences to earn 5 stars. These can include gourmet restaurants, on-site gyms, saunas and spas, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their exceptional standard of service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may even offer extra touches like a welcome gift.