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Our top choices for Santo Domingo hotels

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza, 14.5 km from Santo Domingo
8.8 out of 10, Excellent, (12,137 reviews)
"All was amazing, food and stay"
United States
JOSE LUIS
The price is ₩169,788
₩202,897 total
includes taxes & fees
Feb 10 - Feb 11
Camino Real Aeropuerto Mexico

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City
4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.8 out of 10, Exceptional, (2,709 reviews)
"Always a wonderful stay. Great staff, comfortable room and great restaurant."
Canada
John
The price is ₩241,980
₩289,166 total
includes taxes & fees
Feb 23 - Feb 24
Zocalo Central & Rooftop Mexico City

Barceló México Reforma

Barceló México Reforma
4.5 star property
11.9 km from Santo Domingo
9.4 out of 10, Exceptional, (5,192 reviews)
"Great place to stay "
United States
Alejandro
The price is ₩187,041
₩223,514 total
includes taxes & fees
Feb 16 - Feb 17
Barceló México Reforma

Hotel Embassy

Hotel Embassy
3.0 star property
Roma Norte, 10.5 km from Santo Domingo
8.6 out of 10, Excellent, (3,300 reviews)
"Clean, comfy, nice staff and great location. "
United States
Shay
The price is ₩60,189
₩71,926 total
includes taxes & fees
Feb 2 - Feb 3
Hotel Embassy

Hotel Juarez

Hotel Juarez
2.5 star property
Historic Center, 12.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1,861 reviews)
"great location, excellent room!"
Canada
Catalina
The price is ₩47,220
₩56,428 total
includes taxes & fees
Jan 30 - Jan 31
Hotel Juarez

Hotel Catedral

Hotel Catedral
4.0 star property
Historic Center, 12.4 km from Santo Domingo
9.4 out of 10, Exceptional, (2,751 reviews)
"Excelente hotel!!"
Mexico
Olga
The price is ₩320,220
₩382,663 total
includes taxes & fees
Jan 31 - Feb 1
Hotel Catedral

Hotel Punto MX

Hotel Punto MX
3.5 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,517 reviews)
"Very clean hotel and breakfast was great. "
Canada
Jesse
The price is ₩75,605
₩90,348 total
includes taxes & fees
Feb 2 - Feb 3
Hotel Punto MX

Historico Central Hotel

Historico Central Hotel
4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2,397 reviews)
"Staff was welcoming , left goodies in our room, arranged taxi service and was excellent ! "
United States
Susan
The price is ₩209,233
₩250,033 total
includes taxes & fees
Jan 28 - Jan 29
Historico Central Hotel

Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto
3.5 star property
Venustiano Carranza, 14.3 km from Santo Domingo
8.8 out of 10, Excellent, (3,353 reviews)
"Loved this place"
United States
Jorge
The price is ₩181,398
₩216,771 total
includes taxes & fees
Jan 30 - Jan 31
Fiesta Inn Ciudad de Mexico Aeropuerto

Hotel Principal

Hotel Principal
4.0 star property
Historic Center, 11.9 km from Santo Domingo
9.0 out of 10, Wonderful, (1,020 reviews)
"I had a good time there with my family."
United States
Claudia
The price is ₩74,208
₩88,678 total
includes taxes & fees
Jan 28 - Jan 29
Hotel Principal

Casa Decu

Casa Decu
4.0 star property
Hipódromo, 8.9 km from Santo Domingo
9.4 out of 10, Exceptional, (846 reviews)
"Very pleasant stay and nice rooms and service. Great location "
United States
Michal
Casa Decu

Eurostars Zona Rosa Suites

Eurostars Zona Rosa Suites
4.0 star property
Zona Rosa, 10.8 km from Santo Domingo
8.8 out of 10, Excellent, (1,009 reviews)
"Amazing location and the staff really friendly. The room clean and a lot of space. Highly recommended. "
United States
Gustavo
The price is ₩109,099
₩130,373 total
includes taxes & fees
Feb 27 - Feb 28
Eurostars Zona Rosa Suites

Hotel PF

Hotel PF
3.5 star property
Zona Rosa, 10.6 km from Santo Domingo
9.0 out of 10, Wonderful, (2,357 reviews)
"Ideally located comfortable and clean hotel for a reasonable cost. "
United States
Toni
The price is ₩118,042
₩141,060 total
includes taxes & fees
Feb 9 - Feb 10
Hotel PF

Grand Prix-WeEnjoyHotels-Aeropuerto

Grand Prix-WeEnjoyHotels-Aeropuerto
3.5 star property
Granjas México, 10.8 km from Santo Domingo
9.0 out of 10, Wonderful, (4,129 reviews)
"Great stay "
United States
Sarmad
The price is ₩125,080
₩149,471 total
includes taxes & fees
Feb 1 - Feb 2
Grand Prix-WeEnjoyHotels-Aeropuerto

Sheraton Maria Isabel Mexico City Reforma

Sheraton Maria Isabel Mexico City Reforma
4.0 star property
Colonia Cuauhtémoc, 11 km from Santo Domingo
9.2 out of 10, Wonderful, (2,188 reviews)
"Amazing hotel and location!"
Canada
Ligia
The price is ₩206,024
₩246,199 total
includes taxes & fees
Feb 27 - Feb 28
Sheraton Maria Isabel Mexico City Reforma

KALI Centro Mexico City

KALI Centro Mexico City
3.0 star property
Downtown Mexico City, 11.2 km from Santo Domingo
9.4 out of 10, Exceptional, (377 reviews)
"Great hotel with all of the expected amenities and close to el centro historico. Friendly staff. "
United States
Autumn
KALI Centro Mexico City

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG
3.0 star property
14.7 km from Santo Domingo
9.2 out of 10, Wonderful, (1,078 reviews)
"The breakfast was delicious "
United States
Mireya
The price is ₩102,906
₩122,973 total
includes taxes & fees
Feb 1 - Feb 2
Holiday Inn Express Mexico Basilica by IHG

Courtyard Mexico City Airport

Courtyard Mexico City Airport
4.0 star property
Venustiano Carranza, 14.8 km from Santo Domingo
9.4 out of 10, Exceptional, (1,806 reviews)
"Staff was great, clean and conveniently located, great option for overnight airport stays"
United States
Mauricio
The price is ₩259,763
₩310,417 total
includes taxes & fees
Jan 30 - Jan 31
Courtyard Mexico City Airport

Fiesta Inn Periferico Sur

Fiesta Inn Periferico Sur
3.5 star property
Coyoacan, 2.9 km from Santo Domingo
8.8 out of 10, Excellent, (1,151 reviews)
"Great hotel "
United States
Slawomir
The price is ₩127,705
₩152,607 total
includes taxes & fees
Jan 31 - Feb 1
Fiesta Inn Periferico Sur

Geneve Ciudad de México

Geneve Ciudad de México
4.0 star property
Zona Rosa, 10.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1,796 reviews)
"Room was clean and hotel located in a great spot."
Canada
Andreas
The price is ₩202,239
₩241,675 total
includes taxes & fees
Feb 22 - Feb 23
Geneve Ciudad de México
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco

Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.

La Condesa

Fashionable and popular with young professionals, Condesa boasts international restaurants, bars, and nightclubs. Stroll along tree-lined avenues, admire Art Deco architecture, and visit landmarks like Edificio San Martín and Basurto Building.

Historic Center

Historic center with 1,550 significant buildings, the neighborhood offers museums like MUNAL and Palacio de Bellas Artes. Enjoy upscale eateries, fashionable stores, and pedestrianized streets for easy exploration.

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

Frequently asked questions

What is Santo Domingo like?
Travelers to Mexico City's Santo Domingo neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels should I expect to find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodations in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals in Santo Domingo.
Where can I learn more about changing or cancelling my trip to Santo Domingo?
For additional details about updating your trip to Santo Domingo or cancelling it, click here.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro, and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.