National Car Rentals in Panama City

Compare car suppliers to unlock big savings, and package your flight, hotel, and car to save even more.

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Enjoy maximum flexibility with penalty-free cancellation on most car rentals.

At Expedia, we are proud to work with National Car Rental due to their history of superior customer service as well their large fleet of premier vehicles. Start browsing through the great selection of rental cars by entering your search preferences into our online booking wizard and sorting through everything from spacious SUVs to compact luxury cars. Meaning, whether you need an economy car for a quick business trip or a roomy vehicle to fit the entire family on a long road trip, we’ve got you covered. And, what’s more, we always offer National Car Rental Panama City cars at the lowest possible prices. Our prices on National Car Rental rentals in Panama City can’t be beat. Get started and peruse our myriad of cheap deals and discounts on rental cars for your time in Panama City today.