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Our top choices for St. Louis Science Center hotels

Indoor pool

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 1 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Was perfect for a family stay. Nice rooms, quiet, close to Zoo and Science center."
United States
Joseph
The price is ₩178,817
₩210,877 total
includes taxes & fees
Feb 16 - Feb 17
Hampton Inn & Suites St. Louis at Forest Park
Lobby

Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
2 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,005 reviews)
"Room was clean and the staff was great. "
United States
Stephen
The price is ₩168,294
₩196,784 total
includes taxes & fees
Feb 12 - Feb 13
Drury Inn & Suites St. Louis Forest Park
Seasonal outdoor pool

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Clean room, friendly staff, nice on site amenities "
United States
Russell
The price is ₩256,121
₩345,187 total
includes taxes & fees
Feb 11 - Feb 12
The Royal Sonesta Chase Park Plaza St. Louis
Lobby

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (705 reviews)
"Room was clean nice staff"
United States
Brandon
The price is ₩203,433
₩239,906 total
includes taxes & fees
Feb 22 - Feb 23
AC Hotel St. Louis Central West End
Terrace/patio

Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 0.9 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,001 reviews)
"My family and I had a great experience—staff were courteous and attentive, and the hotel room was very clean and well maintained. "
United States
Kelsey
The price is ₩190,818
₩223,122 total
includes taxes & fees
Mar 8 - Mar 9
Home2 Suites by Hilton St. Louis/Forest Park
Courtyard

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown, 2.7 km from St. Louis Science Center
9.0 out of 10, Wonderful, (667 reviews)
"Staff was amazing and hotel was super clean. Great locations with easy access. Valet was fast and took great care of us. "
United States
Kyle
The price is ₩197,579
₩231,027 total
includes taxes & fees
Mar 2 - Mar 3
Element St. Louis Midtown
Bar (on property)

Aloft St. Louis Cortex

Aloft St. Louis Cortex
3.0 star property
Central West End, 1.8 km from St. Louis Science Center
8.6 out of 10, Excellent, (850 reviews)
"Great Stay "
United States
Brandon Russell
The price is ₩176,504
₩206,384 total
includes taxes & fees
Feb 12 - Feb 13
Aloft St. Louis Cortex
In-room safe, desk, blackout drapes, iron/ironing board

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 1.3 km from St. Louis Science Center
8.2 out of 10, Very Good, (1,002 reviews)
"Good breakfast and perfect location. "
United States
Chaquita
The price is ₩178,817
₩210,877 total
includes taxes & fees
Feb 22 - Feb 23
DoubleTree by Hilton St. Louis Forest Park
Outdoor spa tub

The West End

The West End
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
8.4 out of 10, Very Good, (428 reviews)
"Great stay!"
United States
Shaniqua
The price is ₩124,474
₩174,817 total
includes taxes & fees
Feb 9 - Feb 10
The West End
Restaurant

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 1.7 km from St. Louis Science Center
8.2 out of 10, Very Good, (1,005 reviews)
"Room was super clean, bed was comfy and staff was very nice and helpful. I would definitely stay there again. "
United States
Nicole
The price is ₩169,772
₩216,265 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Indigo St Louis - Central West End by IHG
Lobby

White House at Grand Central

White House at Grand Central
4.0 star property
3 km from St. Louis Science Center
8.4 out of 10, Very Good, (127 reviews)
"Very clean and very friendly people "
United States
Mary
The price is ₩142,257
₩226,250 total
includes taxes & fees
Feb 15 - Feb 16
White House at Grand Central
Standard Double Room | Premium bedding, pillowtop beds, desk, laptop workspace

Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 1.8 km from St. Louis Science Center
7.6 out of 10, Good, (1,341 reviews)
" The staff was nice and welcoming."
United States
Shari
Forest Park Hotel by MDR
Suite, Private Bathroom (Diamonds and Pearls Luxury Suite) | Premium bedding, iron/ironing board, free WiFi, bed sheets

Central West End B&B

Central West End B&B
3.5 star property
Central West End, 3 km from St. Louis Science Center
7.8 out of 10, Good, (54 reviews)
"My husband & I were very impressed with the hostess Ms. Henrietta Taylor she made us feel at home with her hospitality. She keeps the establishment immaculate, and served a scrumptious homemade breakfast! I highly recommend this bed & breakfast in the Central West End of St. Louis, Missouri to all family & friends! 2 Thumbs Up 👍👍!"
United States
Tammy
The price is ₩240,944
₩303,125 total
includes taxes & fees
Feb 9 - Feb 10
Central West End B&B
Superior Room, 1 King Bed (Smoke Free) | Desk, blackout drapes, iron/ironing board, free cribs/infant beds

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
The Hill, 1.8 km from St. Louis Science Center
5.8 out of 10, (1,001 reviews)
"Very helpful staff. "
United States
Jared
The price is ₩111,230
₩130,061 total
includes taxes & fees
Mar 1 - Mar 2
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
Front of property

Grand Center Inn

Grand Center Inn
3.0 star property
3.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (75 reviews)
"Clean room. Excellent host Eric! Historic home Eric very attentive and helpful with all tips about St. Louis!"
United States
Pamela
The price is ₩261,975
₩308,945 total
includes taxes & fees
Feb 9 - Feb 10
Grand Center Inn
Courtyard

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
4.3 km from St. Louis Science Center
9.4 out of 10, Exceptional, (474 reviews)
"Great place to stay, friendly staff, nice room, bathroom, and TV. "
United States
Natalie
The price is ₩222,679
₩256,054 total
includes taxes & fees
Mar 1 - Mar 2
The Knight Center at Washington University
Property amenity

Moonrise Hotel

Moonrise Hotel
4.0 star property
3.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (1,920 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
United States
Jaden
The price is ₩182,107
₩216,578 total
includes taxes & fees
Feb 9 - Feb 10
Moonrise Hotel
Terrace/patio

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (868 reviews)
"We always enjoy our stay here nice clean and great location "
United States
Dominique
The price is ₩160,478
₩196,261 total
includes taxes & fees
Feb 22 - Feb 23
Courtyard by Marriott St. Louis Brentwood
Indoor pool

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station
3.0 star property
Downtown West, 5.3 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,340 reviews)
"Amazing hotel and staff!! "
United States
Alexandra
The price is ₩174,148
₩207,111 total
includes taxes & fees
Feb 12 - Feb 13
Drury Inn & Suites St. Louis Union Station
Terrace/patio

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
3.7 km from St. Louis Science Center
8.8 out of 10, Excellent, (1,056 reviews)
"Clean room and great staff"
United States
Chenier
The price is ₩174,455
₩205,733 total
includes taxes & fees
Feb 22 - Feb 23
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to St. Louis Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Indoor pool
Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
9.4
Exceptional
1,003 reviews
View
Lobby
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.4
Exceptional
1,005 reviews
View
Seasonal outdoor pool
The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
9.0
Wonderful
1,001 reviews
View
Lobby
AC Hotel St. Louis Central West End
4.0 star property
9.0
Wonderful
705 reviews
View
Terrace/patio
Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
8.6
Excellent
1,001 reviews
View

Top St. Louis Science Center Hotel Reviews

Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park

10/10 Excellent
"Clean room with lots of space, nice size bathroom, comfortable bed, they had a lot of options for breakfast and it tasted really good. Complementary breakfast and dinner and fountain drinks. Microwave and fridge in the room. Nice staff and easy check in. They have a little market in there as well which was nice so you can buy Tylenol and such without leaving the hotel. I was really impressed with this hotel. "
Ashley 1-night trip
Posted 1 day ago
Drury Inn & Suites St. Louis Forest Park

Hotels near other St. Louis Science Center attractions

Forest Park

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.
See properties
Grand Basin looking from top of Art Hill in Forest Park, St. Louis, Missouri

Forest Park

4.6/5 (2,094 reviews)
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
See properties

Frequently asked questions

What's the area like around St. Louis Science Center?
St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, check out the 66 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near St. Louis Science Center?
Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good options within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.
How many hotels will I be able to find near St. Louis Science Center?
Expedia has 66 hotels and other accommodations within a mile from St. Louis Science Center.
If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available near St. Louis Science Center.
Where can I learn more about changing or cancelling my trip in the area near St. Louis Science Center?
To access more information about changing or cancelling your stay near St. Louis Science Center, go to https://www.expedia.com/service/.
What can I see and do near St. Louis Science Center?
Cathedral Basilica of St. Louis, St. Louis Art Museum, and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box, and Sheldon Concert Hall are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater, and Peabody Opera House.