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Our top choices for Santa Clara hotels

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
10.2 km from Santa Clara
8.6 out of 10, Excellent, (2,448 reviews)
"Very friendly staff, impeccable room, free airport shuttle, nice food..... we had a great stay!"
United Kingdom
Renildis
The price is ₩172,395
₩189,635 total
includes taxes & fees
Mar 5 - Mar 6
Crowne Plaza Panama Airport by IHG

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
9.7 km from Santa Clara
9.0 out of 10, Wonderful, (72 reviews)
"Clean room, friendly staff."
United States
Richard
The price is ₩173,552
₩225,270 total
includes taxes & fees
Feb 24 - Feb 25
ORHO HOTEL BOUTIQUE PANAMA Airport

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.4 out of 10, Very Good, (1,858 reviews)
"Very nice staff and confortable stay"
United States
MARIA
The price is ₩180,857
₩198,943 total
includes taxes & fees
Feb 24 - Feb 25
Riande Aeropuerto Hotel & Casino

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (666 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ₩389,408
₩428,356 total
includes taxes & fees
Mar 7 - Mar 8
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 2.8 km from Santa Clara
9.4 out of 10, Exceptional, (219 reviews)
"Really loved this place"
United States
Alejandra
The price is ₩119,751
₩198,543 total
includes taxes & fees
Mar 2 - Mar 3
Arcadia Condo Suites

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
3.2 km from Santa Clara
8.8 out of 10, Excellent, (1,007 reviews)
"Staff was good rooms clean just a good experience "
United States
Adrian
The price is ₩152,437
₩167,681 total
includes taxes & fees
Mar 23 - Mar 24
Courtyard by Marriott Panama Metromall

Villa Caprichosa

Villa Caprichosa
3.0 star property
28.6 km from Santa Clara
9.8 out of 10, Exceptional, (51 reviews)
"Nice view of the beach "
United States
Lourdes
The price is ₩361,568
₩397,725 total
includes taxes & fees
Feb 25 - Feb 26
Villa Caprichosa

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 8.3 km from Santa Clara
8.8 out of 10, Excellent, (157 reviews)
"Very good hotel, well located. "
United States
Andrés
The price is ₩195,246
₩214,770 total
includes taxes & fees
Mar 1 - Mar 2
Renaissance Panama City Hotel

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 8.4 km from Santa Clara
9.8 out of 10, Exceptional, (202 reviews)
"Very clean modern rooms, spacious hotel, delicious breakfast, very friendly staff!"
Canada
Sheldon
The price is ₩237,550
₩261,305 total
includes taxes & fees
Mar 7 - Mar 8
Hyatt Regency Panama City

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 3 km from Santa Clara
9.0 out of 10, Wonderful, (318 reviews)
"Great hotel and services"
United States
Pedro
The price is ₩334,580
₩368,038 total
includes taxes & fees
Mar 7 - Mar 8
The Westin Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 7.8 km from Santa Clara
9.0 out of 10, Wonderful, (1,011 reviews)
"Beautiful hotel, great service. Breakfast buffet is amazing. "
United States
Tamara
The price is ₩417,972
₩459,770 total
includes taxes & fees
Mar 22 - Mar 23
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 6.1 km from Santa Clara
8.6 out of 10, Excellent, (1,011 reviews)
"Good locatiion"
United States
Caren
The price is ₩193,945
₩213,340 total
includes taxes & fees
Mar 8 - Mar 9
Sheraton Grand Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (5,017 reviews)
"Great pool and restaurant."
Canada
Terri
The price is ₩174,547
₩192,002 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Riu Plaza Panama

Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 11.6 km from Santa Clara
9.4 out of 10, Exceptional, (304 reviews)
"Great staff and Hotel."
United States
Joshua
Hotel San Felipe

Taboga Palace Spa Hotel

Taboga Palace Spa Hotel
3.5 star property
28.1 km from Santa Clara
9.2 out of 10, Wonderful, (45 reviews)
"David and his wife provide a truly fantastic at such a quaint and beautiful property. The pool and views are incredible. We are having such a great time and plan to return in the future."
Canada
Marc-Andre
The price is ₩188,015
₩206,817 total
includes taxes & fees
Feb 24 - Feb 25
Taboga Palace Spa Hotel

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 8.2 km from Santa Clara
8.4 out of 10, Very Good, (1,431 reviews)
"Clean room,helpful staff around the hotel,good food options"
United States
Umar
The price is ₩319,629
₩351,592 total
includes taxes & fees
Feb 28 - Mar 1
Megapolis Hotel Panamá

W Panama

W Panama
5.0 star property
Campo Alegre, 8.4 km from Santa Clara
9.0 out of 10, Wonderful, (1,003 reviews)
"Second time staying and it was flawless."
United States
Anthony
The price is ₩311,237
₩342,361 total
includes taxes & fees
Mar 25 - Mar 26
W Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 14.7 km from Santa Clara
8.2 out of 10, Very Good, (229 reviews)
"Great rooms, pleasant staff, lovely location, lots of eats and drinks options"
United States
Rajiv Sachin
The price is ₩128,530
₩141,387 total
includes taxes & fees
Feb 25 - Feb 26
MARINN Tropical Vibes Hotel

The Beach House

The Beach House
3.0 star property
Amador, 15 km from Santa Clara
8.4 out of 10, Very Good, (416 reviews)
"We loved the staff, room & view! "
United States
Jerome
The Beach House

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1,160 reviews)
"Clean, nice staff and super close to the airport "
United States
Leticia
The price is ₩136,672
₩150,339 total
includes taxes & fees
Mar 4 - Mar 5
Ramada Plaza by Wyndham Panama Punta Pacifica
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top Santa Clara Hotel Reviews

Frequently asked questions

What is Santa Clara like?
Travelers will be sure to find plenty to entertain them in Panama City's Santa Clara neighborhood.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about picking new dates or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What are the top things to see and do in Santa Clara?
A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia, and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.