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Our top choices for Santa Clara hotels

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 8.2 km from Santa Clara
8.4 out of 10, Very Good, (1361)
"Lovely breakfast and very clean and friendly staff!!!"
United States
Ravindra
Megapolis Hotel Panamá

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 2.8 km from Santa Clara
9.6 out of 10, Exceptional, (650)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ₩325,959
₩358,562 total
includes taxes & fees
Jan 25 - Jan 26
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Obarrio, 7.5 km from Santa Clara
8.8 out of 10, Excellent, (1012)
"Great hotel. Great spa"
United States
Robert
The price is ₩195,672
₩215,239 total
includes taxes & fees
Jan 16 - Jan 17
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.5 star property
9.7 km from Santa Clara
9.0 out of 10, Wonderful, (46)
"Great staff and nice boutique hotel "
United States
Margie
The price is ₩173,930
₩225,761 total
includes taxes & fees
Jan 10 - Jan 11
ORHO HOTEL BOUTIQUE PANAMA Airport

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 8 km from Santa Clara
9.0 out of 10, Wonderful, (4803)
"Great place to stay"
United States
Maria Teresa
The price is ₩177,492
₩195,241 total
includes taxes & fees
Jan 22 - Jan 23
Hotel Riu Plaza Panama

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista, 8.4 km from Santa Clara
7.8 out of 10, Good, (1003)
"Clean, nice location, bery friendly staff"
United States
Hadjera
The price is ₩136,318
₩149,950 total
includes taxes & fees
Jan 11 - Jan 12
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
9.6 km from Santa Clara
8.6 out of 10, Excellent, (2385)
"Great staff and close to the airport "
United States
CARLOS ROBERTO
The price is ₩159,436
₩175,380 total
includes taxes & fees
Jan 15 - Jan 16
Crowne Plaza Panama Airport by IHG

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
19.1 km from Santa Clara
8.0 out of 10, Very Good, (1000)
"Beautiful property and amazing staff"
United States
CARMEN
The price is ₩356,876
₩392,563 total
includes taxes & fees
Jan 18 - Jan 19
The Westin Playa Bonita Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 6.6 km from Santa Clara
9.6 out of 10, Exceptional, (1137)
"The room was clean and the location was great."
United States
Wendy
The price is ₩157,697
₩173,467 total
includes taxes & fees
Jan 13 - Jan 14
Ramada Plaza by Wyndham Panama Punta Pacifica

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 8.4 km from Santa Clara
9.4 out of 10, Exceptional, (2148)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is ₩156,465
₩172,112 total
includes taxes & fees
Jan 18 - Jan 19
Plaza Paitilla Inn Hotel

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 8.6 km from Santa Clara
8.8 out of 10, Excellent, (1000)
"Amazing location in downtown Panama City. Staff is super "
Canada
Karianne
The price is ₩305,364
₩335,903 total
includes taxes & fees
Jan 16 - Jan 17
Hilton Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 14.7 km from Santa Clara
8.2 out of 10, Very Good, (211)
"Perfect location, nice rooms, nice views"
United States
Ever
The price is ₩100,731
₩110,804 total
includes taxes & fees
Jan 12 - Jan 13
MARINN Tropical Vibes Hotel

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 11.5 km from Santa Clara
9.2 out of 10, Wonderful, (1002)
"Great hotel!"
United States
Alejandro
Central Hotel Panama Casco Viejo

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 2.8 km from Santa Clara
9.4 out of 10, Exceptional, (185)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is ₩120,354
₩199,543 total
includes taxes & fees
Feb 9 - Feb 10
Arcadia Condo Suites

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Campo Alegre, 8.4 km from Santa Clara
9.8 out of 10, Exceptional, (162)
"Breakfast was so good , hotel was clean "
United States
ankit
The price is ₩227,844
₩250,628 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt Regency Panama City

Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
Punta Paitilla, 8.1 km from Santa Clara
8.6 out of 10, Excellent, (1490)
"Great place! "
Mexico
Bridget
Decapolis Hotel Panama City

InterContinental Miramar Panama by IHG

InterContinental Miramar Panama by IHG
4.0 star property
Bella Vista, 9 km from Santa Clara
8.6 out of 10, Excellent, (546)
"Great location, food excellent, staff excellent, beautiful area with the pool"
Canada
Veronique
The price is ₩252,046
₩309,229 total
includes taxes & fees
Jan 11 - Jan 12
InterContinental Miramar Panama by IHG

Holiday Inn Panama Distrito Financiero by IHG

Holiday Inn Panama Distrito Financiero by IHG
4.0 star property
Campo Alegre, 8 km from Santa Clara
8.8 out of 10, Excellent, (1001)
"Clean room, great staff. "
United States
Carline
The price is ₩127,912
₩148,698 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Panama Distrito Financiero by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
8.7 km from Santa Clara
8.6 out of 10, Excellent, (1845)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is ₩181,251
₩199,376 total
includes taxes & fees
Jan 15 - Jan 16
Riande Aeropuerto Hotel & Casino

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 11.4 km from Santa Clara
9.8 out of 10, Exceptional, (572)
"The staf, the people on the main entrance door, the concierne, everything is perfect. "
United States
alejandro
The price is ₩463,319
₩509,658 total
includes taxes & fees
Feb 2 - Feb 3
Sofitel Legend Casco Viejo, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Clara

Find the best Santa Clara areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Crown Casino. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Top Santa Clara Hotel Reviews

Frequently asked questions

What is Santa Clara like?
Travelers will be sure to find plenty to entertain them in Panama City's Santa Clara neighborhood.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best options available in Santa Clara.
Where can I learn more about changing or cancelling my trip to Santa Clara?
To access more information about picking new dates or cancelling your trip to Santa Clara, go to https://www.expedia.com/service/.
What are the top things to see and do in Santa Clara?
A few places to visit in the area around Santa Clara include Estadio Rommel Fernandez, Plaza de Francia, and Atrio Mall. While you're out sightseeing, Monte Oscuro and Los Pueblos Commercial Center are a couple of additional sights to visit in Panama City.