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Oct 23 - Oct 25
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Our top choices for San Francisco hotels

A balcony with wicker chairs and a view of the cityscape.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,400 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is ₩137,584
₩151,342 total
includes taxes & fees
Nov 9 - Nov 10
Ramada Plaza by Wyndham Panama Punta Pacifica
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

2. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"I enjoyed my stay at this hotel, great location , breakfast was fresh every morning, room was clean and the staff was friendly. I definitely would be staying here again.."
United States
SHARROW
The price is ₩168,126
₩184,939 total
includes taxes & fees
Nov 7 - Nov 8
Courtyard by Marriott Panama Multiplaza Mall
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

3. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,007 reviews)
"It was a great stay! I would stay here again!"
United States
Brittney
The price is ₩163,522
₩179,874 total
includes taxes & fees
Nov 1 - Nov 2
Aloft by Marriott Panama
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

4. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"
United States
Nicole
The price is ₩231,186
₩254,305 total
includes taxes & fees
Nov 1 - Nov 2
Sheraton Grand Panama
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

5. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,810 reviews)
"The best hotel in Panama"
United States
dencel
The price is ₩211,942
₩233,136 total
includes taxes & fees
Oct 31 - Nov 1
Megapolis Hotel Panamá
A view from a balcony with a cityscape in the background, featuring tall buildings and a body of water.

6. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,249 reviews)
"I love the breakfast with it's increible view of the bay"
United States
Milton
The price is ₩174,070
₩191,477 total
includes taxes & fees
Nov 1 - Nov 2
Plaza Paitilla Inn Hotel
A modern building with a glass facade, a curved structure, and a flat roof.

7. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,728 reviews)
"Food was limited, but I enjoyed our stay ..3"
United States
Mechalia
The price is ₩116,701
₩128,371 total
includes taxes & fees
Oct 31 - Nov 1
Decapolis Hotel Panama City
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

8. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,130 reviews)
"Good hotel, can be better for the price"
United States
Jorge
The price is ₩172,530
₩189,783 total
includes taxes & fees
Nov 1 - Nov 2
Las Americas Golden Tower Panama
A poolside area with lounge chairs and a view of the ocean.

9. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,005 reviews)
"Beautiful hotel, Excellent hotel with great views, very clean the food was good"
United States
GIORIA
The price is ₩381,043
₩419,147 total
includes taxes & fees
Nov 21 - Nov 22
JW Marriott Panama
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

10. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (689 reviews)
"Great place!"
United States
david
The price is ₩261,370
₩287,507 total
includes taxes & fees
Oct 30 - Oct 31
Residence Inn by Marriott Panama City
A modern outdoor swimming pool with a clear view of a tall building in the background.

11. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (39 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is ₩205,380
₩225,918 total
includes taxes & fees
Nov 9 - Nov 10
Dovle Residences by HMS-Preferred Member
Balcony

12. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (66 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is ₩155,330
₩207,349 total
includes taxes & fees
Oct 25 - Oct 26
San Francisco by Wynwood House
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

13. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (236 reviews)
"very nice place to stay"
United States
purabi
The price is ₩62,092
₩254,312 total
includes taxes & fees
Oct 26 - Oct 27
Boutique Apartments Panamá Coco del Mar
A rooftop pool with lounge chairs, offering a city view.

14. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (49 reviews)
"Staff was great. Room has spectacular views. Air conditioning was great, super quiet in the bedroom. Rooftop pool and patio was delightful. Loved our stay!"
Canada
Gary
The price is ₩44,873
₩194,507 total
includes taxes & fees
Oct 25 - Oct 26
Boutique Apartments Atlapa
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

15. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is ₩59,478
₩268,794 total
includes taxes & fees
Nov 2 - Nov 3
Living 73 Panamá by Boutique Apartments
A high-rise hotel with a modern design, featuring a prominent entrance and multiple balconies.

16. Modern Apartments at the Hub City views

Modern Apartments at the Hub City views
3.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is ₩156,317
₩171,949 total
includes taxes & fees
Oct 26 - Oct 27
Modern Apartments at the Hub City views
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

17. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (4 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ₩126,572
₩342,089 total
includes taxes & fees
Nov 1 - Nov 2
Wanders Panama by Boutique Apartments
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

18. Pty Loft-style 1br Cincuentenario Bay

Pty Loft-style 1br Cincuentenario Bay
2.0 star property
San Francisco
10.0 out of 10, Exceptional, (1 review)
The price is ₩142,695
₩202,498 total
includes taxes & fees
Oct 23 - Oct 24
Pty Loft-style 1br Cincuentenario Bay
A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

19. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (16 reviews)
"Very well located and cheap and convenient"
United States
SANTIAGO
The price is ₩77,510
₩85,261 total
includes taxes & fees
Oct 22 - Oct 23
Casa Orquídea
A modern high-rise building with a prominent 'Living' sign, large windows, and a sleek architectural design.

20. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
8.0 out of 10, Very good, (4 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is ₩106,392
₩117,031 total
includes taxes & fees
Oct 23 - Oct 24
Modern Apartments PH Living 73 SF
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in San Francisco

A balcony with wicker chairs and a view of the cityscape.

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
View
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

Aloft by Marriott Panama

3.5 star property
San Francisco
View
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

Sheraton Grand Panama

4.0 star property
San Francisco
View
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

Megapolis Hotel Panamá

4.5 star property
San Francisco
View
9.6
Exceptional
1,400 reviews
9.0
Wonderful
1,002 reviews
8.8
Excellent
1,007 reviews
8.8
Excellent
1,000 reviews
8.6
Excellent
1,810 reviews
The price is ₩137,584
₩151,342 total
includes taxes & fees
Nov 9 - Nov 10
The price is ₩168,126
₩184,939 total
includes taxes & fees
Nov 7 - Nov 8
The price is ₩163,522
₩179,874 total
includes taxes & fees
Nov 1 - Nov 2
The price is ₩231,186
₩254,305 total
includes taxes & fees
Nov 1 - Nov 2
The price is ₩211,942
₩233,136 total
includes taxes & fees
Oct 31 - Nov 1
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • No Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Hotels recommended for families in San Francisco

A balcony with wicker chairs and a view of the cityscape.

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,400)
The price is ₩137,584
₩151,342 total
includes taxes & fees
Nov 9 - Nov 10
Ramada Plaza by Wyndham Panama Punta Pacifica

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Lotería Station or Santo Tomás Station to see more of the city.

Top San Francisco Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"Great location, easy access to the coffee shop, restaurants, fast food and multiplaza mall. The breakfast, staff, room and amenities excellent!"
janilla Melissa 4-night trip
Posted 4 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on our traveler data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Ramada Plaza by Wyndham Panama Punta Pacifica and Decapolis Hotel Panama City.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 323 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Via Espana, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Pacific Center are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Bingo 90, Soho City Center, and National Shrine of the Heart of Mary. When you're sightseeing in Panama City, Panama Viejo Museum and Multicentro Panama are also worth a stop.