Find hotels in Sant' Ambrogio, Florence from ₩72,300

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Our top choices for Sant' Ambrogio hotels

An outdoor patio with seating and potted plants.

1. Hotel Regency

Hotel Regency
5.0 star property
Sant' Ambrogio
9.4 out of 10, Exceptional, (475 reviews)
"Wonderful staff and super nice rooms."
United States
Amy
The price is ₩387,924
₩450,423 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Regency
A nighttime view of a courtyard with a paved path, surrounded by buildings and trees.

2. Palazzo Monnalisa

Palazzo Monnalisa
5.0 star property
Sant' Ambrogio
9.0 out of 10, Wonderful, (817 reviews)
"We loved our stay! The breakfast was amazing"
United States
Laura
The price is ₩489,294
₩561,929 total
includes taxes & fees
Nov 15 - Nov 16
Palazzo Monnalisa
A spacious lobby with high ceilings, arched windows, and a variety of seating arrangements including sofas and chairs.

3. The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
5.0 star property
Sant' Ambrogio
10.0 out of 10, Exceptional, (28 reviews)
"Amazing hotel, very dedicated staff, great location."
Canada
Josianne
The price is ₩584,250
₩666,382 total
includes taxes & fees
Dec 1 - Dec 2
The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World
A rectangular pool with wooden deck and lounge chairs, surrounded by greenery and a white wall.

4. Villa Tortorelli

Villa Tortorelli
Sant' Ambrogio
9.4 out of 10, Exceptional, (93 reviews)
"Room was clean, easy check-in, easy access to location, staff were freindly and helpful. Special shout out to Alicia!!"
Canada
Ahmad
The price is ₩72,300
₩97,310 total
includes taxes & fees
Nov 15 - Nov 16
Villa Tortorelli
A building with multiple windows, a balcony with balustrade, and storefronts with awnings.

5. Anchor Santa Croce

Anchor Santa Croce
Sant' Ambrogio
9.8 out of 10, Exceptional, (9 reviews)
"Amazing place to stay. Clean, close to main touristic attractions in Florence."
Canada
Adina
The price is ₩130,919
₩161,791 total
includes taxes & fees
Dec 9 - Dec 10
Anchor Santa Croce
An open balcony with a table and two chairs, a view of a garden with various plants and flowers, and a white door frame.

6. Hotel Villa Liana

Hotel Villa Liana
3.0 star property
Sant' Ambrogio
8.8 out of 10, Excellent, (380 reviews)
"Wonderfully helpful staff!!!"
United States
Amber
The price is ₩112,741
₩141,795 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Villa Liana
A hotel room with a large bed, a desk with a magazine, a chair, and a window with curtains.

7. Alfieri9

Alfieri9
3.0 star property
Sant' Ambrogio
9.6 out of 10, Exceptional, (176 reviews)
"Beautiful place and the staff was very helpful"
United States
Xavier
The price is ₩118,014
₩147,595 total
includes taxes & fees
Nov 18 - Nov 19
Alfieri9
A room with a bed, a TV, a sofa, a staircase, and a view of greenery outside.

8. Firenze Suite

Firenze Suite
Sant' Ambrogio
10.0 out of 10, Exceptional, (11 reviews)
"Beautiful. It’s an old monastery. Great location for getting around. Would definitely stay there again."
United States
Ricky
The price is ₩154,495
₩187,725 total
includes taxes & fees
Nov 22 - Nov 23
Firenze Suite
A hallway with a fireplace, a sofa with a patterned cushion, and a large plant.

9. Dimora del Cardinale - Residenza d'epoca

Dimora del Cardinale - Residenza d'epoca
Sant' Ambrogio
10.0 out of 10, Exceptional, (81 reviews)
"Great room location. Great bed and pillows. Very well located. Loved the historical prestige of the place. Staff was friendly and helpful."
Canada
Roberto
The price is ₩131,604
₩221,810 total
includes taxes & fees
Nov 29 - Nov 30
Dimora del Cardinale - Residenza d'epoca
A courtyard with purple wisteria vines, potted red and white flowers, and a building with green shutters.

10. Locanda Orchidea - B&B

Locanda Orchidea - B&B
Sant' Ambrogio
9.2 out of 10, Wonderful, (271 reviews)
"Great place"
United States
Patricio
The price is ₩109,104
₩137,795 total
includes taxes & fees
Nov 15 - Nov 16
Locanda Orchidea - B&B
A modern bathroom with a bathtub, a large mirror, and a television.

11. Palazzo dei Ciompi Suites

Palazzo dei Ciompi Suites
Sant' Ambrogio
7.6 out of 10, Good, (427 reviews)
"The reception was helpful, and we were able to leave our luggage in a safe place while we waited for our checkin. The look of the paint mural on the ceiling was beautiful. There was a lot of space for 4 people to stay comfortably and separate bedrooms were nice."
Canada
Harshita
The price is ₩90,747
₩117,608 total
includes taxes & fees
Nov 26 - Nov 27
Palazzo dei Ciompi Suites
A hotel room with a wooden wardrobe, a bed with white bedding, a nightstand with a vase of flowers, and a suitcase.

12. Numa Florence Fiesolana

Numa Florence Fiesolana
Sant' Ambrogio
7.4 out of 10, Good, (3 reviews)
"Great"
United States
Charleston
The price is ₩134,696
₩165,945 total
includes taxes & fees
Dec 1 - Dec 2
Numa Florence Fiesolana
A hotel entrance with a sign reading "HOTEL BODONI" and the number "27" on the wall.

13. Hotel Bodoni

Hotel Bodoni
2.0 star property
Sant' Ambrogio
8.2 out of 10, Very good, (896 reviews)
"great stay"
Canada
Ethan
The price is ₩80,737
₩102,145 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Bodoni
A room with a dining table, chairs, a sofa, a lamp, a TV, and a window with curtains.

14. Tosca

Tosca
Sant' Ambrogio
10.0 out of 10, Exceptional, (3 reviews)
"Very clean property, very good communication Good place 👌"
United States
Manolo
The price is ₩78,076
₩145,150 total
includes taxes & fees
Nov 15 - Nov 16
Tosca
A balcony with potted flowers and a view of a historic building with a dome.

15. B&B di Piazza del Duomo

B&B di Piazza del Duomo
Sant' Ambrogio
9.2 out of 10, Wonderful, (305 reviews)
"Great stay for a single traveler, very close to all the shops you would need, very nice staff, great place to stay."
United States
Antonio
The price is ₩129,319
₩160,031 total
includes taxes & fees
Nov 16 - Nov 17
B&B di Piazza del Duomo
A dining area with tables and chairs, a fireplace, and a large mural on the wall.

16. I Quattro Poeti

I Quattro Poeti
Sant' Ambrogio
8.4 out of 10, Very good, (174 reviews)
"We like our stay and the location is good."
Sweden
joegie
The price is ₩91,647
₩118,592 total
includes taxes & fees
Nov 15 - Nov 16
I Quattro Poeti
A spacious hall with a patterned floor, arched ceilings, and classical statues.

17. Residenza D'Epoca Sant'Egidio

Residenza D'Epoca Sant'Egidio
Sant' Ambrogio
7.4 out of 10, Good, (155 reviews)
"Loved the Italian charm"
United States
Sheila
The price is ₩69,705
₩94,456 total
includes taxes & fees
Dec 10 - Dec 11
Residenza D'Epoca Sant'Egidio
A multi-story building with a symmetrical facade, evenly spaced windows, and a central entrance.

18. PALAZZO TESTA - LOCAZIONE TURISTICA

PALAZZO TESTA - LOCAZIONE TURISTICA
Sant' Ambrogio
8.0 out of 10, Very good, (2 reviews)
"Great place to stay good location"
United Kingdom
ian
The price is ₩123,721
₩153,873 total
includes taxes & fees
Nov 15 - Nov 16
PALAZZO TESTA - LOCAZIONE TURISTICA
A modern kitchen with a wooden ceiling, a dining area with a patterned rug, and a bar area with a TV.

19. Oriuolo 5

Oriuolo 5
Sant' Ambrogio
8.0 out of 10, Very good, (1 review)
"localização excelente! apenas 5 minutos andando da Duomo e uns 15 minutos da estação de trem. valeu muito a pena para o nosso esquema de viagem! nao recomendo apenas para quem nao gosta de barulho. embaixo do apartamento é uma zona de bares que fica com muito barulho até de madrugada. e tambem para quem tem problemas de mobilidade, porque são 70 degraus no prédio para chegar no apartamento o apartamento muito bem conservado. tem o básico necessário para passar alguns dias de...
Brazil
Flavia
The price is ₩141,000
₩254,371 total
includes taxes & fees
Nov 23 - Nov 24
Oriuolo 5
A modern bedroom with a bed, a dresser, a mirror, and a bedside table.

20. Almea Florence

Almea Florence
Sant' Ambrogio
The price is ₩109,346
₩138,060 total
includes taxes & fees
Nov 15 - Nov 16
Almea Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most.
A river with buildings on the right bank.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Sant' Ambrogio Hotel Reviews

A four-poster bed with a floral canopy, a wooden floor, a bedside table with a book and a cup, and a television on a shelf.
Hotel David

Hotel David

Hotel David
Oltrarno

10/10 Excellent

Absolutely beautiful hotel. They have thought of everything- so comfortable, welcoming, and enjoyable!
United States
Leila
Reviewed April 6, 2025
Hotel David

Frequently Asked Questions

What's it like in Sant' Ambrogio?

Guests are sure to enjoy their time checking out all that Florence's Sant' Ambrogio neighborhood has to offer. Be sure to check out Piazza Massimo D'Azeglio and Church of Santa Maria Maddalena dei Pazzi as part of your Sant' Ambrogio travel plans.

What's the best accommodation in Sant' Ambrogio?

Based on our traveler data, Hotel Bodoni is one of the top choices for your stay in Sant' Ambrogio. This hotel is a short 7-minute walk from Piazza del Duomo, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include Hotel Bavaria and Hotel Regency.

How many hotels will I find in Sant' Ambrogio?

If you're searching for places to stay in Florence, Expedia has something to meet your needs with 549 Sant' Ambrogio hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in Sant' Ambrogio, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review top deals in Sant' Ambrogio.

Where can I learn more about changing or cancelling my trip to Sant' Ambrogio?

To find more details about rescheduling or cancelling your trip to Sant' Ambrogio, head over to our customer service page.

What is there to do around this Florence neighborhood?

Landmarks in Sant' Ambrogio that you won't want to miss include Great Synagogue of Florence and Church of Santa Maria Maddalena dei Pazzi. Piazza Massimo D'Azeglio and Mercato di Sant'Ambrogio are also a couple of places to visit in the neighborhood. Piazza del Duomo and Piazza di Santa Maria Novella are some favorite places to visit in the area around Sant' Ambrogio. When you're sightseeing in Florence, Jewish Museum and FiesoleBike Day Tours are also worth a stop.