What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here .

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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Dates

February 2026

March 2026

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Our top choices for Serra Mesa hotels

The Bristol Hotel San Diego

9.9 km from Serra Mesa

Zoe

₩640,664 total

includes taxes & fees

Feb 9 - Feb 10

Westgate Hotel

9.9 km from Serra Mesa

Ray

Palihotel San Diego Gaslamp Quarter

Gaslamp Quarter, 10.1 km from Serra Mesa

phuc

₩203,448 total

includes taxes & fees

Jan 25 - Jan 26

Hard Rock Hotel San Diego

Gaslamp Quarter, 10.8 km from Serra Mesa

Erica

₩648,850 total

includes taxes & fees

Feb 4 - Feb 5

Manchester Grand Hyatt San Diego

Marina District, 10.7 km from Serra Mesa

Michelle

₩403,218 total

includes taxes & fees

Jan 23 - Jan 24

Embassy Suites by Hilton San Diego Bay Downtown

Marina District, 10.6 km from Serra Mesa

Kathy

₩377,127 total

includes taxes & fees

Jan 27 - Jan 28

The Sofia Hotel

10 km from Serra Mesa

Guadalupe

5 outdoor pools, a heated pool, pool umbrellas, sun loungers

Paradise Point Resort & Spa

Mission Bay, 9.9 km from Serra Mesa

samantha

₩314,142 total

includes taxes & fees

Jan 21 - Jan 22

Margaritaville Hotel San Diego Gaslamp Quarter

Gaslamp Quarter, 10.5 km from Serra Mesa

Ginger

₩381,434 total

includes taxes & fees

Jan 21 - Jan 22

2 outdoor pools, a heated pool, sun loungers

The Dana on Mission Bay

Mission Bay, 10.1 km from Serra Mesa

Megan

₩303,195 total

includes taxes & fees

Feb 9 - Feb 10

3 restaurants, breakfast, lunch, dinner served; Regional cuisine

Wyndham San Diego Bayside

9.9 km from Serra Mesa

David

₩282,380 total

includes taxes & fees

Jan 22 - Jan 23

Gaslamp Plaza Suites

Gaslamp Quarter, 10 km from Serra Mesa

SONIA

₩207,853 total

includes taxes & fees

Jan 28 - Jan 29

Premium bedding, pillowtop beds, desk, laptop workspace

Staypineapple, Hotel Z, Gaslamp San Diego

Gaslamp Quarter, 10.4 km from Serra Mesa

Simran

₩205,037 total

includes taxes & fees

Jan 21 - Jan 22

Pacific View Inn

North Pacific Beach, 11.1 km from Serra Mesa

Peter

₩187,066 total

includes taxes & fees

Jan 25 - Jan 26

The Wayfarer San Diego

Mission Beach, 10.9 km from Serra Mesa

Angela

₩284,756 total

includes taxes & fees

Jan 21 - Jan 22

Del Mar Beach Hotel

21.4 km from Serra Mesa

Frank

Legacy Resort Hotel & Spa

5.8 km from Serra Mesa

Christopher

Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk

The DEXTRO Little Italy, BW Premier Collection

9.3 km from Serra Mesa

Zoraima

₩146,487 total

includes taxes & fees

Jan 21 - Jan 22

Inn By The Sea La Jolla

13.7 km from Serra Mesa

Sydney

₩270,011 total

includes taxes & fees

Jan 22 - Jan 23

Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)

San Diego Mission Bay Resort

Mission Bay, 7.2 km from Serra Mesa

Dani

₩335,777 total

includes taxes & fees

Feb 2 - Feb 3

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Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

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Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

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Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

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Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

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Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach Farmers Market, you won't get bored spending a day wandering around this part of San Diego.

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Top Serra Mesa Hotel Reviews

Hampton Inn & Suites by Hilton San Diego SeaWorld

10/10 Excellent

"Perfect stay — highly recommend. A near-new hotel with spotless, modern rooms in a very convenient location. The beds were incredibly comfortable, making it easy to relax and unwind. The breakfast buffet was a real highlight — especially the Hampton waffles, which were absolutely delicious. The facilities were well maintained and enjoyable, with a warm pool and hot tub that we loved using. The staff were exceptionally friendly and helpful throughout our stay. A massive shout-out to Malarie, who went above and beyond to make our experience truly superb and accommodating. Thank you so much 🤗🙏"