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Our top choices for Serra Mesa hotels

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
9.9 km from Serra Mesa
8.6 out of 10, Excellent, (1,478 reviews)
"Newly remodeled rooms, clean and wonderful staff. "
United States
Zoe
The Bristol Hotel San Diego

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.5 km from Serra Mesa
9.0 out of 10, Wonderful, (1,207 reviews)
"Perfect location in the Gaslamp District. Rooms were large & clean with friendly staff. "
United States
Ginger
The price is ₩275,235
₩378,501 total
includes taxes & fees
Jan 29 - Jan 30
Margaritaville Hotel San Diego Gaslamp Quarter

Westgate Hotel

Westgate Hotel
4.5 star property
9.9 km from Serra Mesa
9.0 out of 10, Wonderful, (1,006 reviews)
"Great stay"
United States
ESMERALDA
Westgate Hotel

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 10.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,007 reviews)
"Great location and stay. "
United States
Simran
The price is ₩144,861
₩210,248 total
includes taxes & fees
Jan 26 - Jan 27
Staypineapple, Hotel Z, Gaslamp San Diego

The Dana on Mission Bay

The Dana on Mission Bay
3.5 star property
Mission Bay, 10.1 km from Serra Mesa
9.0 out of 10, Wonderful, (4,037 reviews)
"Great location, friendly attentive staff and great tv setup in rooms."
United States
John
The price is ₩232,655
₩301,062 total
includes taxes & fees
Feb 22 - Feb 23
The Dana on Mission Bay

Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 10.1 km from Serra Mesa
8.6 out of 10, Excellent, (2,197 reviews)
"Excellent location, wonderful staff."
United States
phuc
The price is ₩168,273
₩195,094 total
includes taxes & fees
Jan 27 - Jan 28
Palihotel San Diego Gaslamp Quarter

The Wayfarer San Diego

The Wayfarer San Diego
4.0 star property
Mission Beach, 10.9 km from Serra Mesa
9.4 out of 10, Exceptional, (1,723 reviews)
"Great location. Easy access to beach and boardwalk."
United States
Fernando
The price is ₩250,506
₩287,945 total
includes taxes & fees
Jan 26 - Jan 27
The Wayfarer San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 10.8 km from Serra Mesa
9.0 out of 10, Wonderful, (3,262 reviews)
"Great place to stay!"
United States
CINDY
The price is ₩567,590
₩728,121 total
includes taxes & fees
Feb 3 - Feb 4
Hard Rock Hotel San Diego

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,260 reviews)
"Friendly staff, great location, excellent value overall "
United States
Maryann
The price is ₩232,948
₩270,091 total
includes taxes & fees
Jan 30 - Jan 31
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Inn By The Sea La Jolla

Inn By The Sea La Jolla
3.5 star property
13.7 km from Serra Mesa
9.4 out of 10, Exceptional, (1,776 reviews)
"A lovely stay in a quaint area!"
United States
Sydney
The price is ₩233,489
₩268,387 total
includes taxes & fees
Jan 26 - Jan 27
Inn By The Sea La Jolla

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 9.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,902 reviews)
"Clean room, helpful and friendly staff, great location to walk to restaurants. "
United States
Annette
La Pensione Hotel

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
5.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,944 reviews)
"Great relaxing hotel"
United States
Christopher
Legacy Resort Hotel & Spa

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 10 km from Serra Mesa
9.0 out of 10, Wonderful, (1,028 reviews)
"Clean quiet friendly helpful staff convenient location will stay there again"
United States
David
The price is ₩159,493
₩181,424 total
includes taxes & fees
Jan 26 - Jan 27
Gaslamp Plaza Suites

Pacific View Inn

Pacific View Inn
2.0 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.0 out of 10, Very Good, (1,006 reviews)
"Very clean and right on the beach. Views were amazing. It is a very active and lively spot in PB. Just a great beach spot, absolutely. "
United States
Alicia
The price is ₩170,058
₩192,072 total
includes taxes & fees
Jan 26 - Jan 27
Pacific View Inn

PB Surf Beachside Inn

PB Surf Beachside Inn
2.5 star property
North Pacific Beach, 11.1 km from Serra Mesa
8.2 out of 10, Very Good, (1,001 reviews)
"Really nice place to stay at"
United States
Alejandro
The price is ₩135,642
₩153,201 total
includes taxes & fees
Jan 27 - Jan 28
PB Surf Beachside Inn

The Shoal La Jolla Beach

The Shoal La Jolla Beach
2.5 star property
13.2 km from Serra Mesa
8.8 out of 10, Excellent, (1,001 reviews)
"Super solid place to stay, clean, great staff, walk to the beach."
United Kingdom
Nick
The price is ₩192,885
₩217,854 total
includes taxes & fees
Jan 26 - Jan 27
The Shoal La Jolla Beach

The Sofia Hotel

The Sofia Hotel
3.5 star property
10 km from Serra Mesa
8.6 out of 10, Excellent, (1,717 reviews)
"We liked our stay"
United States
Vadim
The Sofia Hotel

Humphreys Half Moon Inn

Humphreys Half Moon Inn
3.5 star property
12.3 km from Serra Mesa
9.2 out of 10, Wonderful, (2,747 reviews)
"Great stay, highly recommend."
United States
Ryan
The price is ₩247,288
₩313,514 total
includes taxes & fees
Feb 8 - Feb 9
Humphreys Half Moon Inn

Del Mar Beach Hotel

Del Mar Beach Hotel
2.0 star property
21.4 km from Serra Mesa
9.4 out of 10, Exceptional, (1,008 reviews)
"Great place"
United States
Frank
Del Mar Beach Hotel

Empress Hotel of La Jolla

Empress Hotel of La Jolla
3.0 star property
13.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location"
United States
Rachel
The price is ₩259,568
₩323,586 total
includes taxes & fees
Jan 26 - Jan 27
Empress Hotel of La Jolla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Ocean Beach Farmers Market, you won't get bored spending a day wandering around this part of San Diego.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels will I be able to find in the Serra Mesa area?
Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.
Where can I learn more about changing or cancelling my trip to Serra Mesa?
For more information about picking new dates or cancelling your trip to Serra Mesa, click here.
What can I see and do in this San Diego neighborhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.